Abelacimab (anti-Factor XI) - Primärer Antikörper, specific to F11, >95%, Human IgG1, Antibody of integrin αIIbβ3, Antibody of integrin αIIbβ3

CAS: 2098724-83-3 Cat. No.: Ab175444
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QUALITÄT & REINHEIT Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Mensch
Reactive species
Mensch
Isotype
Human IgG1
Conjugation
Unconjugated
★
Größe
Deutschland (EU)
USA*
Preis
Menge
100μg
Ab175444-100μg
—
Auf Lager ≥10
104,04€
1mg
Ab175444-1mg
—
4 Auf Lager
520,56€
5mg
Ab175444-5mg
—
1 Auf Lager
950,96€
10mg
Ab175444-10mg
Auf Bestellung · 8–12 Wochen
1.514,99€
Enter a quantity for the sizes you want to add.
🧪
Warum diese Qualität

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated für empfindliche chromatographische und analytische Workflows, die minimale Basislinieninterferenzen erfordern.

🌡

Lagerung & Versand

Store at -80°C,Avoid repeated freezing and thawing Versand Dry ice packs + Cold packs. Genaue Spezifikationen finden Sie im chargenspezifischen COA.

📋

Qualitätsdokumente

SDS, COA, Datenblatt und Spezifikationsblatt stehen zum Download bereit. Chargenspezifische COA über Chargennummernsuche abrufbar.

📚

Literaturbeleg

In 0 peer-reviewten Publikationen zu Chromatographie, organischer Synthese und Kreuzkupplungsreaktionen zitiert.

Übersicht

Abelacimab (anti-Factor XI) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab (anti-Factor XI) can be used in thromboembolic disease studies.

Spezifikationen

Product Name
Abelacimab (anti-Factor XI) - Primärer Antikörper, specific to F11, >95%, Human IgG1, Antibody of integrin αIIbβ3
Synonyme
coagulation factor XI antibody | Coagulation factor XIa light chain antibody | F11 antibody | FA11_HUMAN antibody | FXI antibody | MGC141891 antibody | Plasma thromboplastin antecedent antibody | Platelet coagulation factor XI antibody | PTA antibody | Co
Spezifikationen & Reinheit
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemische und physiologische Mechanismen
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Wirtsspezies
Mensch
Spezifität
F11
Konjugation
Unconjugated
Note
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Aktionsart
INHIBITOR
Mechanismus der Wirkung
Antibody of integrin αIIbβ3
Isotyp
Human IgG1
Lichterketten-Typ
lambda
SDS-PAGE
27.4 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 197.4kDa, under non-reducing conditions.
Verfahren zur Reinigung
Protein A purified
Reinheit
>95%
Konzentration
See COA
CAS
2098724-83-3
Product Line
Biologische Produkte
Lagerung und Versand
Form
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Verschickt in
Dry ice packs + Cold packs
Stabilität und Lagerung
Store at -80℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Bilder

Abelacimab (anti-Factor XI) (Ab175444) - SEC
The purity of Abelacimab (anti-Factor XI) (Ab175444) is more than 95% verified by HPLC.

Abelacimab (anti-Factor XI) (Ab175444) - ELISA
Immobilized Human F11-his at 2.0 μg/mL can bind Abelacimab (anti-Factor XI) (Ab175444) with the EC₅₀ of 31.79 ng/mL.

Dokumentation

📋 Sicherheitsdatenblatt (SDS)

Umfassendes Dokument zu Gefahren, Handhabung, Lagerung und Einhaltung regulatorischer Vorschriften.

<<<<<<< HEAD SDS herunterladen → ======= SDS herunterladen → >>>>>>> release248-p3

✅ Analysezertifikat (COA)

Chargenspezifische Qualitätsdaten. Geben Sie Ihre Chargennummer ein, um das genaue COA abzurufen.

COA nachschlagen →

📊 Datenblatt

Kurzübersicht über Produktspezifikationen und Anwendungen.

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🔬 Spezifikationsblatt

Vollständige Qualitätsmerkmale und Akzeptanzkriterien für diese Qualität.

Spezifikationsblatt ansehen →

Erweiterte Daten

Zugehörige Ziele (menschlich)
F11 Tchem Coagulation factor XI (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGA2B Tclin Integrin alpha-IIb (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGB3 Tclin Integrin beta-3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGA2B Tclin Integrin alpha-IIb (36 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
F11 Tchem Coagulation factor XI (1733 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-V/beta-3 (2708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-IIb/beta-3 (3481 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3) (39 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-V/beta-3 and alpha-IIb/beta 3 (49 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-2/beta-3 (21 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-3/beta-3 (47 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Wirkungsmechanismen
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDatumArtikel
ZJ24F0607383ZJ24F0607383Certificate of AnalysisJun 26, 2024 Ab175444
ZJ24F0202895ZJ24F0202895Certificate of AnalysisMar 01, 2024 Ab175444
ZJ24F0202894ZJ24F0202894Certificate of AnalysisMar 01, 2024 Ab175444
ZJ24F0202893ZJ24F0202893Certificate of AnalysisMar 01, 2024 Ab175444
Lösungsrechner
Bewertungen

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