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Aladdin™ Psoralen-PEG3-Biotin , CAS No.A638758
AVAILABLE TO ORDER
Storage
Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Protected from light,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Product introduction：
Psoralen-PEG3-Biotin enables biotinylation of DNA or RNA via UV-light-activated intercalation of the psoralen group with thymine- and other pyrimidine-containing bases to form a covalent bonds.
Features of EZ-Link Psoralen-PEG3-Biotin:
• Biomolecular labeling—biotinylate DNA or RNA (approximately 1 biotin per 10 to 20 bases) without interfering with hybridization
• Photo-reactive—covalent attachment occurs in the presence of UV light (∼350nm) for 10 to 30 minutes
• Psoralen-activated—reacts through a cyclo-addition mechanism with the 5,6 double bond in thymine- and other pyrimidine-containing bases
• Pegylated—spacer arm contains a hydrophilic, 3-unit, polyethylene glycol (PEG) group
• Enhances solubility—pegylation imparts water solubility to the biotinylated molecule, helping to prevent aggregation of biotinylated antibodies stored in solution
• Long reach —spacer arm (total length added to target) is 36.9 angstroms, minimizing steric hindrance for binding interactions with streptavidin
Psoralen-PEG3-Biotin is a photoactivatable reagent for biotinylation of DNA or RNA. Upon activation with UV-Light (∼350nm), the psoralen group reacts with thymine- and other pyrimidine-containing bases to form a covalent bond. The hydrophilicpolyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm also gives this reagent a long and flexible connection to minimize steric hindrance involved with binding to avidin molecules.
We manufacture biotin reagents to ensure the highest possible overall product integrity, consistency and performance for the intended research applications.
Applications:
• Selective labeling of cell surface proteins (Ref.1)
• Biotinylation of hyaluronan (Ref.2)
• Labeling of endotoxin for receptor binding studies (Ref.3)
Features of EZ-Link Psoralen-PEG3-Biotin:
• Biomolecular labeling—biotinylate DNA or RNA (approximately 1 biotin per 10 to 20 bases) without interfering with hybridization
• Photo-reactive—covalent attachment occurs in the presence of UV light (∼350nm) for 10 to 30 minutes
• Psoralen-activated—reacts through a cyclo-addition mechanism with the 5,6 double bond in thymine- and other pyrimidine-containing bases
• Pegylated—spacer arm contains a hydrophilic, 3-unit, polyethylene glycol (PEG) group
• Enhances solubility—pegylation imparts water solubility to the biotinylated molecule, helping to prevent aggregation of biotinylated antibodies stored in solution
• Long reach —spacer arm (total length added to target) is 36.9 angstroms, minimizing steric hindrance for binding interactions with streptavidin
Psoralen-PEG3-Biotin is a photoactivatable reagent for biotinylation of DNA or RNA. Upon activation with UV-Light (∼350nm), the psoralen group reacts with thymine- and other pyrimidine-containing bases to form a covalent bond. The hydrophilicpolyethylene glycol (PEG) spacer arm imparts water solubility that is transferred to the biotinylated molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm also gives this reagent a long and flexible connection to minimize steric hindrance involved with binding to avidin molecules.
We manufacture biotin reagents to ensure the highest possible overall product integrity, consistency and performance for the intended research applications.
Applications:
• Selective labeling of cell surface proteins (Ref.1)
• Biotinylation of hyaluronan (Ref.2)
• Labeling of endotoxin for receptor binding studies (Ref.3)
• Spacer:Extra-Long, Pegylated
• Cell Permeability:Cell-Impermeant
Specifications
Storage
Store at 2-8°C, Protected from light, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Properties
| Reactivity | Light-Activated |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMF(Dimethylformamide),DMSO(Dimethylsulfoxide),Water |
|---|
Solution Calculators
Reviews
Customer Reviews
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