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· · COA & SDS available for every product · Same-day shipping on in-stock items AMG-8718 - Moligand™ , Inhibitor of beta-secretase 1, CAS No.A607608, Inhibitor of beta-secretase 1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
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Why this grade Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Specifications & Purity
Moligand™
Mechanism of action
Inhibitor of beta-secretase 1
Names and Identifiers Canonical Smiles NC1=N[C@]2(CO1)c1cc(C#CC3(C)COC3)cnc1Oc1c2cc(cc1)c1cccnc1F InChIKey GKKFBOARESVMBW-VWLOTQADSA-N INCHI 1S/C25H19FN4O3/c1-24(12-31-13-24)7-6-15-9-19-22(29-11-15)33-20-5-4-16(17-3-2-8-28-21(17)26)10-18(20)25(19)14-32-23(27)30-25/h2-5,8-11H,12-14H2,1H3,(H2,27,30)/t25-/m0/s1 Isomeric SMILES CC1(COC1)C#CC2=CC3=C(N=C2)OC4=C([C@@]35COC(=N5)N)C=C(C=C4)C6=C(N=CC=C6)F PubChem CID 45254510
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Benzopyrans Subclass 1-benzopyrans Intermediate Tree Nodes Chromenopyridines Direct Parent Chromeno[2,3-b]pyridines Alternative Parents Diarylethers Pyranopyridines 2-halopyridines Aryl fluorides Benzenoids Oxazolines Heteroaromatic compounds Oxetanes Isoureas Oxacyclic compounds Dialkyl ethers Carboximidamides Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Hydrocarbon derivatives Amines Organofluorides Molecular Framework Aromatic heteropolycyclic compounds Substituents Chromeno[2,3-b]pyridine - Diaryl ether - Pyranopyridine - 2-halopyridine - Aryl fluoride - Aryl halide - Pyridine - Benzenoid - Heteroaromatic compound - Oxazoline - Isourea - Oxetane - Organic 1,3-dipolar compound - Azacycle - Oxacycle - Ether - Dialkyl ether - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Amine - Hydrocarbon derivative - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as chromeno[2,3-b]pyridines. These are aromatic heteropolycyclic compounds containing pyridine linearly fused to the pyran moiety of a benzofuran ring system. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 442.400 g/mol XLogP3 2.900 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 3 Exact Mass 442.144 Da Monoisotopic Mass 442.144 Da Topological Polar Surface Area 91.900 Ų Heavy Atom Count 33 Formal Charge 0 Complexity 866.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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View Moligand™ grade guide → Related Products AZD3293 (Lanabecestat) - Moligand™, ≥99% , Inhibitor of beta-secretase 1, CAS No.1383982-64-6
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