Cinpanemab (anti-Alpha-synuclein) - Primärer Antikörper, specific to SNCA, >95%, Human IgG1, INHIBITOR of Alpha-synuclein inhibitor, INHIBITOR of Alpha-synuclein inhibitor

CAS: 2094516-02-4 Cat. No.: Ab176594

GRADE & PURITY Animal Free, Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Mensch

Reactive species

Cynomolgus-Affe, Maus, Mensch

Isotype

Human IgG1

Conjugation

Unconjugated

Übersicht

Cinpanemab (anti-Alpha-synuclein) is a human-derived monoclonal antibody that binds to α-synuclein. Cinpanemab (anti-Alpha-synuclein) can be used for the research of Parkinson's disease.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name

Cinpanemab (anti-Alpha-synuclein) - Primärer Antikörper, specific to SNCA, >95%, Human IgG1, INHIBITOR of Alpha-synuclein inhibitor

Synonyme

Alpha synuclein antibody | Alpha-synuclein antibody | Alpha-synuclein, isoform NACP140 antibody | alphaSYN antibody | MGC105443 antibody | MGC110988 antibody | MGC127560 antibody | MGC64356 antibody | NACP antibody | Non A beta component of AD amyloid ant

Spezifikationen & Reinheit

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Wirtsspezies

Mensch

Spezifität

SNCA

Konjugation

Unconjugated

Note

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Aktionsart

INHIBITOR

Mechanismus der Wirkung

INHIBITOR of Alpha-synuclein inhibitor

Isotyp

Human IgG1

Lichterketten-Typ

lambdaC2

SDS-PAGE

29.3 kDa (Light Chain) & 49.7 kDa (Heavy Chain), under reducing conditions; 178.4 kDa, under non-reducing conditions.

Verfahren zur Reinigung

Protein A purified

Reinheit

>95%

Konzentration

See COA

CAS

2094516-02-4

Lagerung und Versand

Form

Liquid

Storage

Store at -80°C,Avoid repeated freezing and thawing

Verschickt in

Dry ice packs + Cold packs

Stabilität und Lagerung

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

Flow Cytometry: Cinpanemab (anti-Alpha-synuclein) (Ab176594)

Cinpanemab (anti-Alpha-synuclein) (Ab176594) - Flow Cytometry
Flow Cytometry analysis of HEK-293 cells labelling Alpha-synuclein (red) with Cinpanemab (anti-Alpha-synuclein) (Ab176594). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Cinpanemab (anti-Alpha-synuclein) (Ab176594)

Cinpanemab (anti-Alpha-synuclein) (Ab176594) - SEC
The purity of Cinpanemab (anti-Alpha-synuclein) (Ab176594) is more than 95% verified by HPLC.

ELISA: Cinpanemab (anti-Alpha-synuclein) (Ab176594)

Cinpanemab (anti-Alpha-synuclein) (Ab176594) - ELISA
Immobilized Recombinant Mouse Alpha-synuclein Protein (rp183595) at 5.0 μg/mL can bind Cinpanemab (anti-Alpha-synuclein) (Ab176594) with the EC₅₀ of 475.3 ng/mL.

Zugehörige Ziele (menschlich)

SNCA Tchem Alpha-synuclein (0 Activities)

Discover Target: SNCA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Wirkungsmechanismen

Häufig gestellte Fragen

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2094516-02-4.

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Cinpanemab (anti-Alpha-synuclein)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.