Cipemastat - Moligand™, 10 mM in DMSO , CAS No.190648-49-8

CAS: 190648-49-8 Cat. No.: C1498914 Molecular Weight: 436.55 PubChem CID: 9824350

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Cipemastat is a potent, competitive inhibitor of human collagenases 1, 2 and 3 with K i s of 3.0, 4.4 and 3.4 nM, respectively.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Product Properties

• Ki Data: MMP-1: Ki= 0.3 nM (human); MMP-13: Ki= 0.53 nM (human); MMP-8: Ki= 4 nM (human); MMP-9: Ki= 59 nM (human); MMP-2: Ki= 154 nM (human); MMP-3: Ki= 56 nM (human); ADAM17: Ki= 230 nM (human)

Names and Identifiers

• Isomeric SMILES: CC1(C(=O)N(C(=O)N1C)C[C@@H]([C@@H](CC2CCCC2)C(=O)N3CCCCC3)C(=O)NO)C
• RTECS: TM4960900
• Alternate CAS: 190648-49-8
• PubChem CID: 9824350
• MeSH Entry Terms: 3(R)-(cyclopentylmethyl)-2(R)-((3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl)-4-oxo-4-piperidinobutyrohydroxamic acid;Ro 32-3555;Ro-32-3555;Ro32-3555
• Molecular Weight: 436.55

Chemical and Physical Properties

• Refractive Index: n20D1.54
• Boil Point(°C): 700.21° C (Predicted)
• Melt Point(°C): 306.12° C (Predicted)