Dansyl Chloride（DNSCl） - Moligand™, ≥98%(HPLC) , CAS No.605-65-2

CAS: 605-65-2 Cat. No.: D133513 Summenformel: C₁₂H₁₂ClNO₂S Molekulargewicht: 269.74 EG-Nummer: 210-092-6

GRADE & PURITY Moligand™, ≥98%(HPLC)

Synonyms

1-Chlorosulfonyl-5-dimethylaminonaphthalene | CHEBI:51907 | DNS chloride | DNSClDNSCl | AM10162 | QMU9166TJ4 | Q409512 | 5-dimethylaminonaphthalenesulfonyl chloride | 1-NAPHTHALENESULFONYL CHLORIDE, 5-(DIMETHYLAMINO)- | 5-Dimethylaminonaphthyl-5-sulfonyl

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Übersicht

Dansyl Chloride, also known as 5-dimethylamino naphthalene-1-sulfonyl chloride, is a pre-column derivatization reagent. After the derivatization reaction, the fluorescent derivatives are analyzed using several analytical methods like NMR, IR, UV-vis, and fluorescence microscopy. Dansyl Chloride is a typical aromatic sulphonyl chloride that reacts with various bases, resulting in derivatives with variable stability.

Specifications

Synonyme

1-Chlorosulfonyl-5-dimethylaminonaphthalene | CHEBI:51907 | DNS chloride | DNSClDNSCl | AM10162 | QMU9166TJ4 | Q409512 | 5-dimethylaminonaphthalenesulfonyl chloride | 1-NAPHTHALENESULFONYL CHLORIDE, 5-(DIMETHYLAMINO)- | 5-Dimethylaminonaphthyl-5-sulfonyl

Spezifikationen & Reinheit

Moligand™, ≥98%(HPLC)

Biochemische und physiologische Mechanismen

Fluorogenic primary amine reactive reagent for N -terminal derivatization of amino acids and peptides, and for polyamine detection by reverse phase HPLC and other analytical procedures.

Anmeldung

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC. Dansyl Chloride is used as a derivatization reagent to study extensive metabolism and low doses of ethinylestradiol administer

Storage

Store at 2-8°C,Protected from light,Argon charged

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥98%(HPLC)

Namen und Kennungen

Pubchem Sid

508811744

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508811744

Kanonisches Lächeln

CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)Cl

IUPAC Name

5-(dimethylamino)naphthalene-1-sulfonyl chloride

InChIKey

XPDXVDYUQZHFPV-UHFFFAOYSA-N

INCHI

1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3

Isomere SMILES

CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)Cl

RTECS

QK3688000

Molekulargewicht

269.74

Reaxy-Rn

2217205

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2217205&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Klasse Naphthalenes
      • Subclass Naphthalene sulfonic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Klasse: Naphthalenes
• Subclass: Naphthalene sulfonic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: 1-naphthalene sulfonic acids and derivatives
• Alternative Parents: Dialkylarylamines Sulfonyls Sulfonyl chlorides Organosulfonic acids and derivatives Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: 1-naphthalene sulfonic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl chloride - Sulfonyl halide - Sulfonyl - Tertiary amine - Organic nitrogen compound - Amine - Organosulfur compound - Organonitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organic oxide - Aromatic homopolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as 1-naphthalene sulfonic acids and derivatives. These are organic aromatic compounds that contain a naphthalene moiety that carries a sulfonic acid group (or a derivative thereof) at the 1-position. Naphthalene is a bicyclic compound that is made up of two fused benzene ring.
• External Descriptors: aminonaphthalene

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in DMF, acetone (50 mg/ml), chloroform, pyridine, benzene, and dioxane. Insoluble in water；Insoluble in water，Soluble in acetone、 chloroform、benzene
• Empfindlichkeit: Sensitive to humidity, light, and heat
• Spezifische Drehung [α]: 1.64
• Siedepunkt (°C): 371.30 °C at 760 mmHg
• Schmelzpunkt (°C): 69-73°C
• Molekulargewicht: 269.750 g/mol
• XLogP3: 3.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 269.028 Da
• Monoisotopic Mass: 269.028 Da
• Topological Polar Surface Area: 45.800 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 363.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1