DMT-2′O-TBDMS-rG(ib) Phosphoramidite - ≥95% , CAS No.147201-04-5

CAS: 147201-04-5 Cat. No.: I191003 Molecular Weight: 970.18 PubChem CID: 135587729

GRADE & PURITY ≥95%

Synonyms

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-N-(2-methylpropanoyl)guanosine | 5'-O-(4,4'-Dimethoxy)-N2-isobutyryl-guanosine 2'-O-[1,1-dimethylethyl)dimethylsilyl-3'-[(2-c

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Product Describtion:

I-bu-rG Phosphoramidite is a phosphinamide monomer which can be used in the synthesis of nucleotides and nucleic acids.

Specifications

Synonyms

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-N-(2-methylpropanoyl)guanosine | 5'-O-(4, 4'-Dimethoxy)-N2-isobutyryl-guanosine 2'-O-[1, 1-dimethylethyl)dimethylsilyl-3'-[(2-c

Specifications & Purity

≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504773403
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773403
• Canonical Smiles: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)O[Si](C)(C)C(C)(C)C
• IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
• InChIKey: PGJKESPHANLWME-FTZVBZPOSA-N
• INCHI: 1S/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(66-68(12,13)49(7,8)9)42(65-67(63-29-17-28-51)57(33(3)4)34(5)6)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/m1/s1
• Isomeric SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)O[Si](C)(C)C(C)(C)C
• PubChem CID: 135587729
• Molecular Weight: 970.18

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Triphenyl compounds

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Triphenyl compounds
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Triphenyl compounds
• Alternative Parents: Ribonucleoside phosphoramidites Glycosylamines 6-oxopurines Hypoxanthines Benzylethers Anisoles Phenoxy compounds Methoxybenzenes N-arylamides Alkyl aryl ethers Pyrimidones Monosaccharides N-substituted imidazoles Vinylogous amides Trialkylheterosilanes Oxolanes Heteroaromatic compounds Silyl ethers Secondary carboxylic acid amides Azacyclic compounds Dialkyl ethers Oxacyclic compounds Organic metalloid salts Nitriles Hydrocarbon derivatives Carbonyl compounds Organic oxides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Triphenyl compound - Ribonucleoside phosphoramidite - Glycosyl compound - N-glycosyl compound - 6-oxopurine - Hypoxanthine - Benzylether - Imidazopyrimidine - Purine - Anisole - Phenoxy compound - Phenol ether - N-arylamide - Methoxybenzene - Alkyl aryl ether - Pyrimidone - Monocyclic benzene moiety - Monosaccharide - N-substituted imidazole - Pyrimidine - Trialkylheterosilane - Imidazole - Heteroaromatic compound - Azole - Oxolane - Vinylogous amide - Carboxamide group - Silyl ether - Secondary carboxylic acid amide - Ether - Organic metalloid salt - Nitrile - Carbonitrile - Oxacycle - Carboxylic acid derivative - Dialkyl ether - Organoheterosilane - Azacycle - Organoheterocyclic compound - Organic oxide - Organic oxygen compound - Cyanide - Organic metalloid moeity - Carbonyl group - Organonitrogen compound - Hydrocarbon derivative - Organooxygen compound - Organosilicon compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as triphenyl compounds. These are aromatic compounds containing a triphenyl moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 970.200 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 22
• Exact Mass: 969.459 Da
• Monoisotopic Mass: 969.459 Da
• Topological Polar Surface Area: 180.000 Ų
• Heavy Atom Count: 68
• Formal Charge: 0
• Complexity: 1690.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

XLogP3