Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items
Why this grade
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
eCF506 is a highly potent inhibitor of the non-receptor tyrosine kinase Src with an IC50 of less than 0.5 nM.
Specifications
Synonyms
derivative 11a
Specifications & Purity
Moligand™, ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of BLK proto-oncogene; Src family tyrosine kinase;Inhibitor of FGR proto-oncogene; Src family tyrosine kinase;Inhibitor of FYN proto-oncogene; Src family tyrosine kinase;Inhibitor o
Purity
≥98%
Names and Identifiers
| Canonical Smiles | CC(C)(C)OC(=O)NC1=C(C=C(C=C1)C2=NN(C3=NC=NC(=C23)N)CCN4CCC(CC4)N(C)C)OC |
|---|---|
| IUPAC Name | tert-butyl N-[4-[4-amino-1-[2-[4-(dimethylamino)piperidin-1-yl]ethyl]pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]carbamate |
| InChIKey | GMPQGWXPDRNCBL-UHFFFAOYSA-N |
| INCHI | 1S/C26H38N8O3/c1-26(2,3)37-25(35)30-19-8-7-17(15-20(19)36-6)22-21-23(27)28-16-29-24(21)34(31-22)14-13-33-11-9-18(10-12-33)32(4)5/h7-8,15-16,18H,9-14H2,1-6H3,(H,30,35)(H2,27,28,29) |
| Isomeric SMILES | CC(C)(C)OC(=O)NC1=C(C=C(C=C1)C2=NN(C3=NC=NC(=C23)N)CCN4CCC(CC4)N(C)C)OC |
| PubChem CID | 121231408 |
| MeSH Entry Terms | eCF506 compound;tert-butyl (4-(4-amino-1-(2-(4-(dimethylamino)piperidin-1-yl)ethyl)-1H-pyrazolo(3,4-d)pyrimidin-3-yl)-2-methoxyphenyl)carbamate |
| Molecular Weight | 510.63 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Taxonomic Classification
Taxonomy Tree
- Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Azoles |
| Subclass | Pyrazoles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylpyrazoles |
| Alternative Parents | Phenylcarbamic acid esters Methoxyanilines Pyrazolo[3,4-d]pyrimidines Anisoles Methoxybenzenes Phenoxy compounds Aminopiperidines Alkyl aryl ethers Aminopyrimidines and derivatives Imidolactams Heteroaromatic compounds Carbamate esters Organic carbonic acids and derivatives Trialkylamines Azacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Organopnictogen compounds Primary amines |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Phenylpyrazole - Phenylcarbamic acid ester - Pyrazolopyrimidine - Methoxyaniline - Pyrazolo[3,4-d]pyrimidine - Phenol ether - Phenoxy compound - Methoxybenzene - Anisole - Alkyl aryl ether - 4-aminopiperidine - Aminopyrimidine - Imidolactam - Benzenoid - Pyrimidine - Monocyclic benzene moiety - Piperidine - Carbamic acid ester - Heteroaromatic compound - Carbonic acid derivative - Tertiary aliphatic amine - Tertiary amine - Ether - Azacycle - Organonitrogen compound - Amine - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Primary amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as phenylpyrazoles. These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group. |
| External Descriptors | Not available |
3D Structure
Interactive Chemical Structure Model
Associated Targets(Human)
SRC Tclin Proto-oncogene tyrosine-protein kinase Src (2 Activities)
YES1 Tclin Tyrosine-protein kinase Yes (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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FRK Tchem Tyrosine-protein kinase FRK (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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FYN Tclin Tyrosine-protein kinase Fyn (2 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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FGR Tchem Tyrosine-protein kinase Fgr (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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LCK Tclin Tyrosine-protein kinase Lck (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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LYN Tclin Tyrosine-protein kinase Lyn (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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BLK Tchem Tyrosine-protein kinase Blk (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ABL1 Tclin Tyrosine-protein kinase ABL1 (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HCK Tclin Tyrosine-protein kinase HCK (1 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
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KCNH2 Tclin HERG (29587 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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KIT Tclin Stem cell growth factor receptor (10667 Activities)
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SRC Tclin Tyrosine-protein kinase SRC (10310 Activities)
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PTK2 Tclin Focal adhesion kinase 1 (4730 Activities)
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CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
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MTOR Tclin Serine/threonine-protein kinase mTOR (13850 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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FYN Tclin Tyrosine-protein kinase FYN (5308 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PDGFRA Tclin Platelet-derived growth factor receptor alpha (5682 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
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CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
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YES1 Tclin Tyrosine-protein kinase YES (2781 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MCF7 (126967 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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HepG2 (196354 Activities)
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MDA-MB-231 (73002 Activities)
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RET Tclin Tyrosine-protein kinase receptor RET (6732 Activities)
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Associated Targets(non-human)
Mus musculus (284745 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Danio rerio (3092 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Plasma (328 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Liver microsome (341 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2422319 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422321 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422322 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422323 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422330 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422331 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422332 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422333 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422336 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422337 | Certificate of Analysis | May 10, 2024 | E610058 |
| H2422338 | Certificate of Analysis | May 10, 2024 | E610058 |
Show more ⌵
Chemical and Physical Properties
| Molecular Weight | 510.600 g/mol |
|---|---|
| XLogP3 | 2.600 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 9 |
| Exact Mass | 510.307 Da |
| Monoisotopic Mass | 510.307 Da |
| Topological Polar Surface Area | 124.000 Ų |
| Heavy Atom Count | 37 |
| Formal Charge | 0 |
| Complexity | 742.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Solution Calculators
Reviews
Customer Reviews
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