Eicosapentaenoic acid ethyl ester - ≥95%, from fish oil , CAS No.84494-70-2

CAS: 84494-70-2 Cat. No.: E1074217 Molecular Weight: 330.51

GRADE & PURITY ≥95%, from fish oil

Synonyms

E-EPA（Fish oil） | EPA ethyl ester（Fish oil） | Ethyl Eicosapentaenoate（Fish oil） | C20:5 (5Z,8Z,11Z,14Z,17Z) ethyl ester（Fish oil） | Icosapent ethyl（Fish oil） | SFE 22:5（Fish oil） | Ethyl (5E,8E,11E,14E,17E)-Icosa-5,8,11,14,17-Pentaenoate（Fish oil） | Icosa

Storage

Protected from light,Room temperature,Argon charged

Shipped In

Normal

Overview

Eicosapentaenoic acid (EPA) ethyl ester is an esterified form of the ω-3 fatty acid EPA. Dietary administration of EPA ethyl ester (41.4 g/100 g of total dietary fatty acids) increases the ex vivo activity of hepatic β-oxidation enzymes.1,2 It also reduces total hepatic triglyceride levels and increases the ω-3 fatty acid content of hepatic triglycerides and phospholipids, as well as increases the total levels of ω-3 fatty acids in rats. EPA ethyl ester (1 g/kg) reverses increases in plasma cholesterol levels and reduces circulating triglyceride levels in rats fed a high-fat diet.3 Formulations containing eicosapentaenoic acid ethyl ester have been used as adjuncts in the treatment of hypertriglyceridemia.（WARNING： This product is not for human or veterinary use.）

Specifications

Synonyms

E-EPA（Fish oil） | EPA ethyl ester（Fish oil） | Ethyl Eicosapentaenoate（Fish oil） | C20:5 (5Z, 8Z, 11Z, 14Z, 17Z) ethyl ester（Fish oil） | Icosapent ethyl（Fish oil） | SFE 22:5（Fish oil） | Ethyl (5E, 8E, 11E, 14E, 17E)-Icosa-5, 8, 11, 14, 17-Pentaenoate（Fish oil） | Icosa

Specifications & Purity

≥95%, from fish oil

Storage

Protected from light, Room temperature, Argon charged

Shipped In

Normal

Purity

≥95%

Names and Identifiers

• Canonical Smiles: CC/C=C/C/C=C/C/C=C/C/C=C/C/C=C/CCCC(=O)OCC
• IUPAC Name: ethyl (5E,8E,11E,14E,17E)-icosa-5,8,11,14,17-pentaenoate
• InChIKey: SSQPWTVBQMWLSZ-LRKAYDMASA-N
• INCHI: 1S/C22H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h5-6,8-9,11-12,14-15,17-18H,3-4,7,10,13,16,19-21H2,1-2H3/b6-5+,9-8+,12-11+,15-14+,18-17+
• Alternate CAS: 86227-47-6
• Molecular Weight: 330.51

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Fatty Acyls
      • Subclass Fatty acid esters

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Fatty Acyls
• Subclass: Fatty acid esters
• Intermediate Tree Nodes: Not available
• Direct Parent: Fatty acid esters
• Alternative Parents: Carboxylic acid esters Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Fatty acid ester - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as fatty acid esters. These are carboxylic ester derivatives of a fatty acid.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Boil Point(°C): 417.0±34.0 °C
• Molecular Weight: 330.500 g/mol
• XLogP3: 6.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 15
• Exact Mass: 330.256 Da
• Monoisotopic Mass: 330.256 Da
• Topological Polar Surface Area: 26.300 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 425.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 5
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 5
• Covalently-Bonded Unit Count: 1

References

1. Chen Xiwen, Niu Xiang, Lai Junying, Tang Jiaxing, Xu Zhiyi, Luo Jiye, Yao Yingbang.  (2024)  Preparation and characterization of Ag conductive adhesive with low resistivity.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS,  35  (28): (1-11).  [PMID:] [10.1007/s10854-024-13621-1]