Anticancer agent. Induces G 2 M cell cycle arrest and apoptosis. Induces caspase-3, -7 and -9 activities. Decreases Bcl-2 expression. Induces mitochondrial release of cytochrome c. Inhibits microtubule polymerization.
Storage
Protected from light, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
This compound belongs to the class of organic compounds known as elemane sesquiterpenoids. These are sesquiterpenoids with a structure based on the elemane skeleton. Elemane is a monocyclic compound consisting of a cyclohexane ring substituted with a methyl group, an ethyl group, and two 1-methylethyl groups at the 1-, 1-, 2-, and 4-position, respectively.
External Descriptors
beta-elemene
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Bi Wang, Pirui Li, Jingjing Yang, Xuhong Yong, Min Yin, Yu Chen, Xu Feng, Qizhi Wang. (2021) Inhibition efficacy of Tetradium glabrifolium fruit essential oil against Phytophthora capsici and potential mechanism. INDUSTRIAL CROPS AND PRODUCTS, [PMID:][10.1016/j.indcrop.2021.114310]
2.Qian Feng, Cai-Zhi Li, Yi-Hua Zou, Xue-Yu Wang, Xia Yang, Rong Zhang*, Zhong-Qiu Liu*, Rong-Rong Zhang. (2025) IL6/CCL2 from M2-polarized microglia promotes breast cancer brain metastasis and the reversal effect of β-elemene. Frontiers in Pharmacology, [PMID:40444044][10.3389/fphar.2025.1547333]
3.Haichun Zeng, Beilin Meng, Jiatong Zeng, Li Rao. (2025) Identification and Characterization of a Novel Multifunctional Terpene Synthase from the Pathogenic Fungus Cochliobolus heterostrophus. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:40401765][10.1021/acs.jafc.5c01176]
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