Ethylenedithiobis(trimethylsilane) [Protecting Reagent for Aldehydes and Ketones] - ≥97%(GC) , CAS No.51048-29-4

CAS: 51048-29-4 Cat. No.: E156242 Molecular Weight: 238.55 Beilstein Registry Number: 2037790 EC Number: 256-935-1

GRADE & PURITY ≥97%(GC)

Synonyms

1,2-Ethanedithiobis(trimethylsilane), >=97.0% | SCHEMBL2000069 | D90529 | FT-0734138 | UNII-VHT6NH5F65 | 3,6-Dithia-2,7-disilaoctane, 2,2,7,7-tetramethyl- | 1,2-BIS(TRIMETHYLSILANYLSULFANYL)ETHANE | F8880-8373 | EN300-1666639 | Ethylenedithiobis(trimethyl

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Specifications

Synonyms

1, 2-Ethanedithiobis(trimethylsilane), >=97.0% | SCHEMBL2000069 | D90529 | FT-0734138 | UNII-VHT6NH5F65 | 3, 6-Dithia-2, 7-disilaoctane, 2, 2, 7, 7-tetramethyl- | 1, 2-BIS(TRIMETHYLSILANYLSULFANYL)ETHANE | F8880-8373 | EN300-1666639 | Ethylenedithiobis(trimethyl

Specifications & Purity

≥97%(GC)

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥97%(GC)

Names and Identifiers

• Pubchem Sid: 488187243
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488187243
• Canonical Smiles: C[Si](C)(C)SCCS[Si](C)(C)C
• IUPAC Name: trimethyl(2-trimethylsilylsulfanylethylsulfanyl)silane
• InChIKey: CBRFJNLREFDKBD-UHFFFAOYSA-N
• INCHI: 1S/C8H22S2Si2/c1-11(2,3)9-7-8-10-12(4,5)6/h7-8H2,1-6H3
• Isomeric SMILES: C[Si](C)(C)SCCS[Si](C)(C)C
• WGK Germany: 3
• Molecular Weight: 238.55
• Beilstein: 2037790
• Reaxy-Rn: 2037789
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2037789&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organometallic compounds
    • Class Organometalloid compounds
      • Subclass Organosilicon compounds
        • Level5 Organoheterosilanes
          • Level6 Trialkylheterosilanes

• Kingdom: Organic compounds
• Superclass: Organometallic compounds
• Class: Organometalloid compounds
• Subclass: Organosilicon compounds
• Intermediate Tree Nodes: Organoheterosilanes
• Direct Parent: Trialkylheterosilanes
• Alternative Parents: Sulfenyl compounds Organic metalloid salts Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Trialkylheterosilane - Organic metalloid salt - Sulfenyl compound - Hydrocarbon derivative - Organic salt - Organosulfur compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as trialkylheterosilanes. These are organoheterosilanes, bearing a silicon atom linked to three alkyl groups and one heteroatom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Moisture sensitive.
• Refractive Index: 1.5
• Flash Point(°F): 152.6 °F
• Flash Point(°C): 67°C(lit.)
• Boil Point(°C): 93-94°C/0.5mmHg
• Molecular Weight: 238.600 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 238.07 Da
• Monoisotopic Mass: 238.07 Da
• Topological Polar Surface Area: 50.600 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 108.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

XLogP3

References

1. Lin Yi, Li Mengyao, Luo Zijin, Meng Yanan, Zong Yan, Ren Hongyu, Yu Xiaolu, Tan Xiaoqiong, Liu Fan, Wei Tuo, Cheng Qiang.  (2025)  Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles.  NATURE MATERIALS,      [PMID:40890498] [10.1038/s41563-025-02320-9]

2. Yan-Bin Teng, Zhi Qiao, Chunya Xie, Xiaona Yang, Xinyu Liu, Zhengrong Zou, Yunchang Xie, Xuan Zhang, Qi Chen.  (2025)  Structural and functional insights into the iminium ion intermediate in AsKslB-mediated Pictet-Spengler reaction.  Synthetic and Systems Biotechnology,      [PMID:41141485] [10.1016/j.synbio.2025.09.017]