Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
A potent inhibitor of Cox-1 and Cox-2
| ALogP | 4.2 |
|---|
| Pubchem Sid | 504750670 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750670 |
| Canonical Smiles | CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O |
| IUPAC Name | 2-(3-fluoro-4-phenylphenyl)propanoic acid |
| InChIKey | SYTBZMRGLBWNTM-UHFFFAOYSA-N |
| INCHI | 1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18) |
| Isomeric SMILES | CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O |
| RTECS | DU8341000 |
| Molecular Weight | 244.27 |
| Reaxy-Rn | 2054451 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2054451&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Biphenyls and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Biphenyls and derivatives |
| Alternative Parents | Phenylpropanoic acids Monocyclic monoterpenoids Aromatic monoterpenoids Fluorobenzenes Aryl fluorides Monocarboxylic acids and derivatives Carboxylic acids Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Biphenyl - 2-phenylpropanoic-acid - P-cymene - Aromatic monoterpenoid - Monocyclic monoterpenoid - Monoterpenoid - Fluorobenzene - Halobenzene - Aryl halide - Aryl fluoride - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organooxygen compound - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organofluoride - Organohalogen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond. |
| External Descriptors | fluorobiphenyl |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 19, 2026 | F134483 | |
| Certificate of Analysis | Oct 11, 2025 | F134483 | |
| Certificate of Analysis | Oct 11, 2025 | F134483 | |
| Certificate of Analysis | Oct 11, 2025 | F134483 | |
| Certificate of Analysis | Aug 11, 2025 | F134483 | |
| Certificate of Analysis | Jul 09, 2025 | F134483 | |
| Certificate of Analysis | Jun 09, 2025 | F134483 | |
| Certificate of Analysis | May 30, 2025 | F134483 | |
| Certificate of Analysis | Jun 26, 2024 | F134483 | |
| Certificate of Analysis | Jun 26, 2024 | F134483 | |
| Certificate of Analysis | Jun 26, 2024 | F134483 | |
| Certificate of Analysis | Jan 04, 2024 | F134483 | |
| Certificate of Analysis | Jan 13, 2023 | F134483 |
| Solubility | Soluble in DMSO (50 mg/ml), methanol (50 mg/ml), ethanol (~100 mg/ml), DMF (~100 mg/ml), and buffers of ionic strength ≥0.1 M and pH ≥7.4 (~5 mg/ml). Insoluble in water, Soluble in DMSO (50 mg/ml), methanol (50 mg/ml), ethanol (~100 mg/ml), DMF (~1 |
|---|---|
| Melt Point(°C) | 113 °C |
| Molecular Weight | 244.260 g/mol |
| XLogP3 | 4.200 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 244.09 Da |
| Monoisotopic Mass | 244.09 Da |
| Topological Polar Surface Area | 37.300 Ų |
| Heavy Atom Count | 18 |
| Formal Charge | 0 |
| Complexity | 286.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Zhentao Li, Zhengzheng Liao, Jinfang Hu, Zilin Chen. (2023) In situ growth of imine-based covalent organic framework as stationary phase for high-efficiency electrochromatographic separation. JOURNAL OF CHROMATOGRAPHY A, [PMID:36881971] [10.1016/j.chroma.2023.463905] |
| 2. Zhipeng Huang, Yang Yang, Junju Mu, Genheng Li, Jianyu Han, Puning Ren, Jian Zhang, Nengchao Luo, Ke-Li Han, Feng Wang. (2023) Controlling the reactions of free radicals with metal-radical interaction. CHINESE JOURNAL OF CATALYSIS, [PMID:] [10.1016/S1872-2067(22)64181-0] |
| 3. Qianqian Shang, Huajing Liu, Hang Mei, Chuixiu Huang, Xiantao Shen. (2022) Multi-extraction system with identical supported semi-liquid membrane: Enhanced stability for coextraction of acidic and basic drugs. TALANTA, [PMID:35462249] [10.1016/j.talanta.2022.123485] |
| 4. Yuemei Cen, Haihang Wang, Ping Wen, Genying Xu, Feng Tian, Fenggang Bian, Xiangqiong Zeng. (2022) The development of an artificial skin membrane mimicking the lipid bilayer structure for in vitro permeation study. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2022.128609] |
| 5. Ruiqin Zhu, Hang Mei, Huajing Liu, Changbao Hong, Xiantao Shen, Chuixiu Huang. (2021) Successive liquid-phase microextraction of acidic and basic analytes. ANALYTICA CHIMICA ACTA, [PMID:35057942] [10.1016/j.aca.2021.339335] |
| 6. Shan Chen, Shu Zhou, Jinli Fu, Sisi Tang, Xiaodan Wu, Pengfei Zhao, Zhaohui Zhang. (2021) A near infrared fluorescence imprinted sensor based on zinc oxide nanorods for rapid determination of ketoprofen. Analytical Methods, 13 (25): (2836-2846). [PMID:34080589] [10.1039/D1AY00555C] |
| 7. Hang Mei, Huajing Liu, Qianqian Shang, Ying Dong, Stig Pedersen-Bjergaard, Chuixiu Huang, Xiantao Shen. (2021) Organic-solvent-free electromembrane extraction based on semi-interpenetrating polymer networks. GREEN CHEMISTRY, 23 (4): (1782-1793). [PMID:] [10.1039/D1GC00148E] |
| 8. Xu Xu, Feng Xue, Liu Zhen, Xue Shan, Zhang Lei. (2021) 3D flower-liked Fe3O4/C for highly sensitive magnetic dispersive solid-phase extraction of four trace non-steroidal anti-inflammatory drugs. MICROCHIMICA ACTA, 188 (2): (1-10). [PMID:33496871] [10.1007/s00604-021-04708-1] |
| 9. Wang Zhongyan, Ren Chunhua, Shang Yuna, Yang Cuihong, Guo Qingxiang, Chu Liping, Liu Jianfeng. (2020) Co-assembled Supramolecular Nanofibers With Tunable Surface Properties for Efficient Vaccine Delivery. Frontiers in Chemistry, [PMID:32850613] [10.3389/fchem.2020.00500] |
| 10. Xuemei Wang, Wei Zhou, Chenlu Wang, Zilin Chen. (2018) Cotton fiber-supported layered double hydroxides for the highly efficient adsorption of anionic organic pollutants in water. NEW JOURNAL OF CHEMISTRY, 42 (12): (9463-9471). [PMID:] [10.1039/C8NJ00678D] |
| 11. Nadeem Muhammad, Qamar Subhani, Fenglian Wang, Dandan Guo, Qiming Zhao, Shuchao Wu, Yan Zhu. (2017) Application of a simple column-switching ion chromatography technique for removal of matrix interferences and sensitive fluorescence determination of acidic compounds (pharmaceutical drugs) in complex samples. JOURNAL OF CHROMATOGRAPHY A, [PMID:28807548] [10.1016/j.chroma.2017.07.007] |
| 12. Luo Zhi-yuan, Li Zhi-yong, Liu Hai-yan, Tang Min-qiong, Shi Zhi-guo. (2015) Click chemistry-based synthesis of water-dispersible hydrophobic magnetic nanoparticles for use in solid phase extraction of non-steroidal anti-inflammatory drugs. MICROCHIMICA ACTA, 182 (15): (2585-2591). [PMID:] [10.1007/s00604-015-1638-x] |
| 13. Zheng-Kang Luo, Hui-Min Qin, Jin-Meng Han, Jin Zhu, Yu-Yu Zeng, Chang-Ping Fan, Shu-Xian Liu, Chao Hao, Jian Zhang, Tao Zhuang. (2024) Novel drug-drug co-amorphous systems of olaparib with nonsteroidal anti-inflammatory drugs with improved solubility, physical stability, antitumor activity and pharmacokinetics. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.jddst.2024.106232] |
| 14. Peng Pan, Sixv Ding, Wang Yang, Yibo Wang, Hua Qian, Ayang Zhao, Wengang Ding. (2025) Flurbiprofen@ZIF-8 nanoformulation with potential for analgesia. BMC Anesthesiology, [PMID:41331754] [10.1186/s12871-025-03467-3] |
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