Ginkgolide J - Moligand™, analytical standard , Antagonist of PAF receptor, CAS No.107438-79-9, Antagonist of PAF receptor

CAS: 107438-79-9 Cat. No.: G114073 Molecular Weight: 424.4 EC Number: 683-250-9

GRADE & PURITY Analytical standard, Moligand™

Synonyms

AKOS025311464 | (1R,3R,6R,7S,8S,9R,10S,13S,16S,17R)-8-Tert-butyl-6,9,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione | Ginkgolide J | Q-100047

Storage

Room temperature

Shipped In

Normal

Specifications

Synonyms

AKOS025311464 | (1R, 3R, 6R, 7S, 8S, 9R, 10S, 13S, 16S, 17R)-8-Tert-butyl-6, 9, 17-trihydroxy-16-methyl-2, 4, 14, 19-tetraoxahexacyclo[8.7.2.01, 11.03, 7.07, 11.013, 17]nonadecane-5, 15, 18-trione | Ginkgolide J | Q-100047

Specifications & Purity

Moligand™, analytical standard

Storage

Room temperature

Shipped In

Normal

Grade

Analytical standard, Moligand™

Action Type

ANTAGONIST

Mechanism of action

Antagonist of PAF receptor

Names and Identifiers

• Canonical Smiles: CC1C(=O)OC2C1(C34C(=O)OC5C3(C2)C6(C(C5O)C(C)(C)C)C(C(=O)OC6O4)O)O
• IUPAC Name: (1R,3R,6R,7S,8S,9R,10S,13S,16S,17R)-8-tert-butyl-6,9,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
• InChIKey: LMEHVEUFNRJAAV-XNSMQBOTSA-N
• INCHI: 1S/C20H24O10/c1-6-12(23)27-7-5-17-11-8(21)9(16(2,3)4)18(17)10(22)13(24)29-15(18)30-20(17,14(25)28-11)19(6,7)26/h6-11,15,21-22,26H,5H2,1-4H3/t6-,7+,8-,9+,10+,11-,15+,17?,18+,19-,20-/m1/s1
• Isomeric SMILES: C[C@@H]1C(=O)O[C@@H]2[C@]1([C@@]34C(=O)O[C@H]5C3(C2)[C@@]6([C@@H]([C@H]5O)C(C)(C)C)[C@H](C(=O)O[C@H]6O4)O)O
• WGK Germany: 3
• Molecular Weight: 424.4
• Reaxy-Rn: 37812273
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37812273&ln=

Associated Targets(Human)

PTAFR Tchem Platelet-activating factor receptor (1 Activities)

Discover Target: PTAFR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

References

1. Junyan Wang, Minmin Huang, Haihong Hu, Lushan Yu, Su Zeng.  (2014)  Pregnane X receptor-mediated transcriptional activation of UDP-glucuronosyltransferase 1A1 by natural constituents from foods and herbs.  FOOD CHEMISTRY,      [PMID:24996308] [10.1016/j.foodchem.2014.05.004]