Glycylglycyl-L-isoleucine - ≥95% , CAS No.69242-40-6

CAS: 69242-40-6 Cat. No.: G186058 Molecular Weight: 245.28

GRADE & PURITY ≥95%

Synonyms

A836406 | DTXSID90427242 | (2S,3S)-2-(2-(2-Aminoacetamido)acetamido)-3-methylpentanoic acid | (2S,3S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-methylpentanoic acid | GLY-GLY-ILE | glycylglycylisoleucine | Glycyl-glycyl-isoleucine | MFCD00047934 | H-Gly

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

H-Gly-Gly-Ile-OH, is a versatile amino acid frequently employed in the fields of biochemistry and molecular biology. Despite being a non-proteinogenic amino acid, it is found abundantly in various biological systems, including plants, animals, and bacteria. This remarkable molecule finds numerous applications in laboratory experiments and scientific research. Among its roles, it is utilized in exploring protein structure and function, as well as investigating enzyme kinetics. Moreover, researchers rely on H-Gly-Gly-Ile-OH in studies concerning membrane transport, signal transduction, metabolic pathways, enzyme-substrate interactions, and gene expression. In the realm of enzymatic reactions, H-Gly-Gly-Ile-OH plays a pivotal role as a substrate for enzymes. Specifically, it facilitates the catalysis of peptide bond formation between amino acids. The enzyme binds to H-Gly-Gly-Ile-OH, ultimately leading to the formation of a peptide bond between two amino acids.

Specifications

Synonyms

A836406 | DTXSID90427242 | (2S, 3S)-2-(2-(2-Aminoacetamido)acetamido)-3-methylpentanoic acid | (2S, 3S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-methylpentanoic acid | GLY-GLY-ILE | glycylglycylisoleucine | Glycyl-glycyl-isoleucine | MFCD00047934 | H-Gly

Specifications & Purity

≥95%

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Canonical Smiles: CCC(C)C(C(=O)O)NC(=O)CNC(=O)CN
• IUPAC Name: (2S,3S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-methylpentanoic acid
• InChIKey: XMPXVJIDADUOQB-RCOVLWMOSA-N
• INCHI: 1S/C10H19N3O4/c1-3-6(2)9(10(16)17)13-8(15)5-12-7(14)4-11/h6,9H,3-5,11H2,1-2H3,(H,12,14)(H,13,15)(H,16,17)/t6-,9-/m0/s1
• Isomeric SMILES: CC[C@H](C)[C@@H](C(=O)O)NC(=O)CNC(=O)CN
• Molecular Weight: 245.28
• Reaxy-Rn: 6409962
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6409962&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Isoleucine and derivatives N-acyl-L-alpha-amino acids Alpha amino acid amides Methyl-branched fatty acids Secondary carboxylic acid amides Amino acids Carboxylic acid salts Carboxylic acids Monocarboxylic acids and derivatives Monoalkylamines Hydrocarbon derivatives Organic oxides Organic salts Carbonyl compounds Organic zwitterions Organopnictogen compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-oligopeptide - Isoleucine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-acyl-l-alpha-amino acid - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Branched fatty acid - Methyl-branched fatty acid - Fatty acyl - Fatty acid - Amino acid or derivatives - Carboxamide group - Carboxylic acid salt - Amino acid - Secondary carboxylic acid amide - Monocarboxylic acid or derivatives - Carboxylic acid - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Primary aliphatic amine - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organic oxide - Organooxygen compound - Primary amine - Amine - Organic salt - Organic zwitterion - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: tripeptide

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 Activities)

Discover Target: SLC15A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Light sensitive
• Molecular Weight: 245.280 g/mol
• XLogP3: -3.000
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 245.138 Da
• Monoisotopic Mass: 245.138 Da
• Topological Polar Surface Area: 122.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 293.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1