GSK1331268 - Moligand™, ≥98% , Allosteric modulator of mGlu 2 receptor, CAS No.1207197-70-3, Allosteric modulator of mGlu 2 receptor

CAS: 1207197-70-3 Cat. No.: G610685 Molecular Weight: 342.83 PubChem CID: 46190878
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
GTPL6253 | BDBM50415292 | 5H2QQ669K9 | AKOS040748457 | GSK1331268 | GSK-1331268 | 2-((4-(5-CHLORO-2-PYRIMIDINYL)-1-PIPERAZINYL)METHYL)-1-METHYL-1H-BENZIMIDAZOLE | Q27077872 | UNII-5H2QQ669K9 | 2-{[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]methyl}-1-methyl-
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
G610685-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$799.90
25mg
G610685-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90
100mg
G610685-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$6,399.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

GSK1331268 is a selective, orally bioavailable positive modulators of mGluR2.

Specifications

Synonyms
GTPL6253 | BDBM50415292 | 5H2QQ669K9 | AKOS040748457 | GSK1331268 | GSK-1331268 | 2-((4-(5-CHLORO-2-PYRIMIDINYL)-1-PIPERAZINYL)METHYL)-1-METHYL-1H-BENZIMIDAZOLE | Q27077872 | UNII-5H2QQ669K9 | 2-{[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]methyl}-1-methyl-
Specifications & Purity
Moligand™, ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ALLOSTERIC MODULATOR
Mechanism of action
Allosteric modulator of mGlu 2 receptor
Purity
≥98%
Names and Identifiers
Canonical SmilesClc1cnc(nc1)N1CCN(CC1)Cc1nc2c(n1C)cccc2
IUPAC Name2-{[4-(5-chloropyrimidin-2-yl)piperazin-1-yl]methyl}-1-methyl-1H-1,3-benzodiazole
InChIKeyIXXZGBOSQDVMTC-UHFFFAOYSA-N
INCHI1S/C17H19ClN6/c1-22-15-5-3-2-4-14(15)21-16(22)12-23-6-8-24(9-7-23)17-19-10-13(18)11-20-17/h2-5,10-11H,6-9,12H2,1H3
Isomeric SMILES CN1C2=CC=CC=C2N=C1CN3CCN(CC3)C4=NC=C(C=N4)Cl
PubChem CID 46190878
Molecular Weight 342.83

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassDiazinanes
SubclassPiperazines
Intermediate Tree Nodes Not available
Direct ParentN-arylpiperazines
Alternative Parents Benzimidazoles  Dialkylarylamines  N-alkylpiperazines  Halopyrimidines  Aralkylamines  Aminopyrimidines and derivatives  N-substituted imidazoles  Benzenoids  Aryl chlorides  Heteroaromatic compounds  Trialkylamines  Azacyclic compounds  Organochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents N-arylpiperazine - Benzimidazole - Dialkylarylamine - Aminopyrimidine - Halopyrimidine - N-alkylpiperazine - Aralkylamine - Aryl chloride - Aryl halide - N-substituted imidazole - Pyrimidine - Benzenoid - Imidazole - Heteroaromatic compound - Azole - Tertiary amine - Tertiary aliphatic amine - Azacycle - Organonitrogen compound - Organochloride - Organohalogen compound - Hydrocarbon derivative - Amine - Organic nitrogen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as n-arylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an aryl group.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
GRM2 Tchem Metabotropic glutamate receptor 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM4 Tchem Metabotropic glutamate receptor 4 (2320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM1 Tchem Metabotropic glutamate receptor 1 (2309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Grm2 Metabotropic glutamate receptor 2 (1326 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews

Customer Reviews

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