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· · COA & SDS available for every product · Same-day shipping on in-stock items GSK417651A - Moligand™ , Channel blocker of TRPC3;Channel blocker of TRPC6, CAS No.G610721, Channel blocker of TRPC3;Channel blocker of TRPC6
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Synonyms
Isoquinoline, 1,2,3,4-tetrahydro-2-((2-((4-methoxyphenyl)amino)-4-thiazolyl)carbonyl)- | HY-147357 | (3,4-dihydroisoquinolin-2(1H)-yl)(2-((4-methoxyphenyl)amino)thiazol-4-yl)methanone | AKOS000617430 | cid_1096735 | N-(4-methoxyphenyl)-4-(1,2,3,4-tetrahyd
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Why this grade Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
Isoquinoline, 1, 2, 3, 4-tetrahydro-2-((2-((4-methoxyphenyl)amino)-4-thiazolyl)carbonyl)- | HY-147357 | (3, 4-dihydroisoquinolin-2(1H)-yl)(2-((4-methoxyphenyl)amino)thiazol-4-yl)methanone | AKOS000617430 | cid_1096735 | N-(4-methoxyphenyl)-4-(1, 2, 3, 4-tetrahyd
Specifications & Purity
Moligand™
Action Type
CHANNEL BLOCKER
Mechanism of action
Channel blocker of TRPC3;Channel blocker of TRPC6
Names and Identifiers Canonical Smiles COc1ccc(cc1)Nc1scc(n1)C(=O)N1CCc2c(C1)cccc2 IUPAC Name N-(4-methoxyphenyl)-4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1,3-thiazol-2-amine InChIKey NTXBDULODNTCKP-UHFFFAOYSA-N INCHI 1S/C20H19N3O2S/c1-25-17-8-6-16(7-9-17)21-20-22-18(13-26-20)19(24)23-11-10-14-4-2-3-5-15(14)12-23/h2-9,13H,10-12H2,1H3,(H,21,22) Isomeric SMILES COC1=CC=C(C=C1)NC2=NC(=CS2)C(=O)N3CCC4=CC=CC=C4C3 PubChem CID 1096735
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Tetrahydroisoquinolines Subclass Not available Intermediate Tree Nodes Not available Direct Parent Tetrahydroisoquinolines Alternative Parents Methoxyanilines Thiazolecarboxamides Phenoxy compounds Methoxybenzenes 2-heteroaryl carboxamides Anisoles 2,4-disubstituted thiazoles Alkyl aryl ethers 2-amino-1,3-thiazoles Tertiary carboxylic acid amides Heteroaromatic compounds Amino acids and derivatives Secondary amines Azacyclic compounds Hydrocarbon derivatives Organic oxides Organopnictogen compounds Molecular Framework Aromatic heteropolycyclic compounds Substituents Tetrahydroisoquinoline - Methoxyaniline - 2-heteroaryl carboxamide - Phenoxy compound - Anisole - Thiazolecarboxamide - Phenol ether - Methoxybenzene - Aniline or substituted anilines - Thiazolecarboxylic acid or derivatives - 2,4-disubstituted 1,3-thiazole - Alkyl aryl ether - Monocyclic benzene moiety - 1,3-thiazol-2-amine - Benzenoid - Thiazole - Heteroaromatic compound - Azole - Tertiary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Ether - Carboxylic acid derivative - Azacycle - Secondary amine - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as tetrahydroisoquinolines. These are tetrahydrogenated isoquinoline derivatives. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 365.500 g/mol XLogP3 4.100 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 4 Exact Mass 365.12 Da Monoisotopic Mass 365.12 Da Topological Polar Surface Area 82.700 Ų Heavy Atom Count 26 Formal Charge 0 Complexity 484.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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