≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
IMR-1A IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.
Targets
Notch (Cell-free assay); Notch (Cell-free assay) 0.5 μM; 2.9 μM(Kd)
| ALogP | 2.29 |
|---|---|
| hba_count | 4 |
| HBD Count | 1 |
| Rotatable Bond | 5 |
| Pubchem Sid | 488191798 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488191798 |
| Canonical Smiles | COC1=C(C=CC(=C1)C=C2C(=O)NC(=S)S2)OCC(=O)O |
| IUPAC Name | 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid |
| InChIKey | DVBJNSKWHSGTDK-BJMVGYQFSA-N |
| INCHI | 1S/C13H11NO5S2/c1-18-9-4-7(2-3-8(9)19-6-11(15)16)5-10-12(17)14-13(20)21-10/h2-5H,6H2,1H3,(H,15,16)(H,14,17,20)/b10-5+ |
| Molecular Weight | 325.36 |
| Reaxy-Rn | 29764446 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29764446&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
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| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2317001 | Certificate of Analysis | Jan 19, 2026 | I412257 |
| C23161047 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| C23161201 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| C23161205 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| C23161230 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| C23161263 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| C23161267 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| C23161270 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| C23161271 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| C2316986 | Certificate of Analysis | Dec 10, 2025 | I412257 |
| Solubility | Solubility (25°C) In vitro DMSO: 6 mg/mL (18.44 mM); Water: Insoluble; Ethanol: Insoluble; |
|---|---|
| DMSO(mg / mL) Max Solubility | 6 |
| DMSO(mM) Max Solubility | 18.4411113843128 |
| Water(mg / mL) Max Solubility | ＜1 |
