Janus Green B - Biological stain, Dye content 65% , CAS No.2869-83-2

CAS: 2869-83-2 Cat. No.: J100932 Molecular Weight: 511.06 EC Number: 220-695-6

GRADE & PURITY Biological Stain, Dye content 65%

Synonyms

C.I. 11050 | Q418288 | CHEBI:21184 | AMY22392 | JanusGreenB | J-017200 | HY-D1122 | Sulphuric acid, chromium potassium salt | 3-(Diethylamino)-7-((4-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride | EINECS 220-695-6 | Phenazinium, 3-(diethylamino)

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

A stain used for histology studies of mitochondria

Specifications

Synonyms

C.I. 11050 | Q418288 | CHEBI:21184 | AMY22392 | JanusGreenB | J-017200 | HY-D1122 | Sulphuric acid, chromium potassium salt | 3-(Diethylamino)-7-((4-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride | EINECS 220-695-6 | Phenazinium, 3-(diethylamino)

Specifications & Purity

Biological stain, Dye content 65%

Biochemical and Physiological Mechanisms

Janus Green B is a stain that interacts with DNA and has been used for histology studies including mitochondrial staining, in which its oxidation and reduction reveals alterations to the electron transfer chain. The stain has been utilized in studies for

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Biological Stain

Names and Identifiers

• Pubchem Sid: 504755027
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504755027
• Canonical Smiles: CCN(CC)C1=CC2=[N+](C3=C(C=CC(=C3)N=NC4=CC=C(C=C4)N(C)C)N=C2C=C1)C5=CC=CC=C5.[Cl-]
• IUPAC Name: 8-[[4-(dimethylamino)phenyl]diazenyl]-N,N-diethyl-10-phenylphenazin-10-ium-2-amine;chloride
• InChIKey: XXACTDWGHQXLGW-UHFFFAOYSA-M
• INCHI: 1S/C30H31N6.ClH/c1-5-35(6-2)26-17-19-28-30(21-26)36(25-10-8-7-9-11-25)29-20-23(14-18-27(29)31-28)33-32-22-12-15-24(16-13-22)34(3)4;/h7-21H,5-6H2,1-4H3;1H/q+1;/p-1
• Isomeric SMILES: CCN(CC)C1=CC2=[N+](C3=C(C=CC(=C3)N=NC4=CC=C(C=C4)N(C)C)N=C2C=C1)C5=CC=CC=C5.[Cl-]
• WGK Germany: 3
• RTECS: SG1633000
• Molecular Weight: 511.06
• Reaxy-Rn: 6764343
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6764343&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Diazanaphthalenes
      • Subclass Benzodiazines
        • Level5 Quinoxalines
          • Level6 Phenazines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Quinoxalines
• Direct Parent: Phenazines and derivatives
• Alternative Parents: Dialkylarylamines Aniline and substituted anilines Pyrazines Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organic chloride salts Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Phenazine - Tertiary aliphatic/aromatic amine - Aniline or substituted anilines - Dialkylarylamine - Monocyclic benzene moiety - Pyrazine - Benzenoid - Heteroaromatic compound - Tertiary amine - Azacycle - Organic chloride salt - Amine - Hydrocarbon derivative - Organopnictogen compound - Organonitrogen compound - Organic nitrogen compound - Organic salt - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as phenazines and derivatives. These are polycyclic aromatic compounds containing a phenazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a pyrazine ring.
• External Descriptors: organic chloride salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (20 mg/ml at 20°C), ethanol, and slightly soluble in alcohol.
• Molecular Weight: 511.100 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 510.23 Da
• Monoisotopic Mass: 510.23 Da
• Topological Polar Surface Area: 48.000 Ų
• Heavy Atom Count: 37
• Formal Charge: 0
• Complexity: 694.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

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