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JTV 519 fumarate - ≥98% , CAS No.1883549-36-7

CAS: 1883549-36-7 Cat. No.: J275634 Molecular Weight: 540.67 PubChem CID: 91826075
COA
JTV 519 fumarate - ≥98% CAS No(1883549-36-7) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
3-(4-Benzylpiperidin-1-yl)-1-(7-methoxy-3,5-dihydro-2H-1,4-benzothiazepin-4-yl)propan-1-one(E)-but-2-enedioicacid | 1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone fumarate
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
J275634-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$129.90
5mg
J275634-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$259.90
10mg
J275634-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$459.90
25mg
J275634-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90
50mg
J275634-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,599.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data 3D Structure Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Product description
Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo.

Specifications

Synonyms
3-(4-Benzylpiperidin-1-yl)-1-(7-methoxy-3, 5-dihydro-2H-1, 4-benzothiazepin-4-yl)propan-1-one(E)-but-2-enedioicacid | 1-(2, 3-Dihydro-7-methoxy-1, 4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone fumarate
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Ca 2+ dependent blocker of SERCA and a partial agonist of ryanodine receptors (RyRs). Displays Ca 2+ -dependent inhibition of SERCA-dependent ATPase activity with IC 50 of 9µM at 0.25 Ca 2+ in cardiac muscle.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note
Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Purity
≥98%
Names and Identifiers
Canonical SmilesCOC1=CC2=C(C=C1)SCCN(C2)C(=O)CCN3CCC(CC3)CC4=CC=CC=C4.C(=CC(=O)O)C(=O)O
IUPAC Name3-(4-benzylpiperidin-1-yl)-1-(7-methoxy-3,5-dihydro-2H-1,4-benzothiazepin-4-yl)propan-1-one;(E)-but-2-enedioic acid
InChIKeyISLOBKLDZGDFTB-WLHGVMLRSA-N
INCHI1S/C25H32N2O2S.C4H4O4/c1-29-23-7-8-24-22(18-23)19-27(15-16-30-24)25(28)11-14-26-12-9-21(10-13-26)17-20-5-3-2-4-6-20;5-3(6)1-2-4(7)8/h2-8,18,21H,9-17,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
Isomeric SMILES COC1=CC2=C(C=C1)SCCN(C2)C(=O)CCN3CCC(CC3)CC4=CC=CC=C4.C(=C/C(=O)O)\C(=O)O
Alternate CAS 145903-06-6（Free Base）
PubChem CID 91826075
Molecular Weight 540.67

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
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Chemical and Physical Properties
SensitivityMoisture sensitive
Solution Calculators
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