Kasugamycin Hydrochloride Monohydrate - 10mM in Water , CAS No.200132-83-8

CAS: 200132-83-8 Cat. No.: K422434 Molecular Weight: 433.84 PubChem CID: 57369825

GRADE & PURITY 10mM in Water

Synonyms

Kasugamycin (hydrochloride hydrate) | D-Chiro-inositol, 3-O-(2-amino-4-((carboxyiminomethyl)amino)-2,3,4,6-tetradeoxy-alpha-d-arabino-hexopyranosyl)-, hydrochloride, hydrate (1:1:1) | AKOS030526701 | S5968 | DTXSID20859996 | UNII-5A9BN7V7QL | 3-O-[2-amino

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Kasugamycin is an aminoglycoside antibiotic that potently inhibits both gram-positive and gram-negative bacteria and blocks translation initiation. To a weaker extent, Kasugamycin also inhibits phytopathogenic microbes. Research shows that Kasugamycin can associate with the 30s ribosomal subunit, which results in the indirect inhibition of the P-site tRNA binding, and blocks protein synthesis.

Specifications

Synonyms

Kasugamycin (hydrochloride hydrate) | D-Chiro-inositol, 3-O-(2-amino-4-((carboxyiminomethyl)amino)-2, 3, 4, 6-tetradeoxy-alpha-d-arabino-hexopyranosyl)-, hydrochloride, hydrate (1:1:1) | AKOS030526701 | S5968 | DTXSID20859996 | UNII-5A9BN7V7QL | 3-O-[2-amino

Specifications & Purity

10mM in Water

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CC1C(CC(C(O1)OC2C(C(C(C(C2O)O)O)O)O)N)N=C(C(=O)O)N.O.Cl
• IUPAC Name: 2-amino-2-[(2R,3S,5S,6R)-5-amino-2-methyl-6-[(2S,3S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxyoxan-3-yl]iminoacetic acid;hydrate;hydrochloride
• InChIKey: URDOPMVCASNBEZ-VHRLMMNYSA-N
• INCHI: 1S/C14H25N3O9.ClH.H2O/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22;;/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24);1H;1H2/t3-,4+,5+,6?,7+,8+,9-,10+,11?,14-;;/m1../s1
• Isomeric SMILES: C[C@@H]1[C@H](C[C@@H]([C@H](O1)OC2[C@@H]([C@H](C([C@@H]([C@@H]2O)O)O)O)O)N)N=C(C(=O)O)N.O.Cl
• PubChem CID: 57369825
• Molecular Weight: 433.84

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Alpha amino acids and derivatives
• Alternative Parents: Cyclohexanols Oxanes Monosaccharides Cyclitols and derivatives Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Monocarboxylic acids and derivatives Carboxylic acids Carboximidamides Amidines Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Alpha-amino acid or derivatives - Cyclohexanol - Oxane - Monosaccharide - Cyclitol or derivatives - Cyclic alcohol - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Monocarboxylic acid or derivatives - Carboxylic acid - Amidine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Hydrochloride - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Alcohol - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Melt Point(°C): 202-230° C
• Molecular Weight: 433.840 g/mol
• Hydrogen Bond Donor Count: 10
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 4
• Exact Mass: 433.146 Da
• Monoisotopic Mass: 433.146 Da
• Topological Polar Surface Area: 222.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 532.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

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