L-Leucine - Animal Free, USP, JP, Moligand™, Ph.Eur., for cell culture, ≥98.5% , CAS No.61-90-5

CAS: 61-90-5 Cat. No.: L774643 Summenformel: C6H13NO2 Molekulargewicht: 131.17 Beilstein Registry Number: 4437 EG-Nummer: 200-522-0
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GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. USP ? United States Pharmacopeia grade — meets USP monograph specs for pharmaceutical use. Use for drug manufacturing, QC, and applications requiring US compendial compliance. JP ? Japanese Pharmacopoeia grade — conforms to JP monograph standards. Use for pharmaceutical products subject to Japanese regulatory requirements. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Ph.Eur. ? European Pharmacopoeia grade — conforms to Ph.Eur. monographs across EU member states. Use for pharmaceutical work needing European compendial compliance. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. ≥98.5%
Storage
Protected from light,Room temperature,Desiccated
Shipped In
Normal
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Size
Deutschland (EU)
USA*
Price
Qty
25g
L774643-GMP-25g
Auf Bestellung · 8–12 Wochen
41,56€
100g
L774643-GMP-100g
Auf Bestellung · 8–12 Wochen
133,55€
500g
L774643-GMP-500g
Auf Bestellung · 8–12 Wochen
520,56€
Enter a quantity for the sizes you want to add.
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Why this grade

Animal Free, USP, JP, Moligand™, Ph.Eur., for cell culture, ≥98.5% Animal Free,für die Zellkultur,JP,Moligand™,Ph.Eur.,USP for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 359 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

L-leucine has been used as a hypertrophic agent to monitor its effects on myotubes. It has also been used as a component of PMG media for culturing yeast.

Specifications

Spezifikationen & Reinheit
Animal Free, USP, JP, Moligand™, Ph.Eur., for cell culture, ≥98.5%
Biochemische und physiologische Mechanismen
Leucine is a non sugar producing essential amino acid. It is a branched chain amino acid and a structural component of proteins. Leucine can have a positive effect on the release of insulin, thereby eliminating toxic sugars in the blood. The degradation o
Storage
Protected from light,Room temperature,Desiccated
Verschickt in
Normal
Note
Animal Free, für die Zellkultur, JP, Moligand™, Ph.Eur., USP
Reinheit
≥98.5%
Namen und Kennungen
Kanonisches Lächeln
CC(C)CC(C(=O)O)N
IUPAC Name
(2S)-2-amino-4-methylpentanoic acid
InChIKey
ROHFNLRQFUQHCH-YFKPBYRVSA-N
INCHI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
Isomere SMILES
CC(C)C[C@@H](C(=O)O)N
WGK Deutschland
1
Molekulargewicht
131.17
Beilstein
4437
Reaxy-Rn
636005
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=636005&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
KlasseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentLeucine and derivatives
Alternative Parents L-alpha-amino acids  Methyl-branched fatty acids  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Leucine or derivatives - Alpha-amino acid - L-alpha-amino acid - Branched fatty acid - Methyl-branched fatty acid - Fatty acid - Fatty acyl - Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxide - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Organic oxygen compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Aliphatic acyclic compound
BeschreibungThis compound belongs to the class of organic compounds known as leucine and derivatives. These are compounds containing leucine or a derivative thereof resulting from reaction of leucine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors Common amino acids
3D-Struktur
Interaktives chemisches Strukturmodell





Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDatumArtikel
GMH2604126Certificate of AnalysisAug 11, 2026 L774643
Chemische und physikalische Eigenschaften
Löslichkeit18.9 g/L
EmpfindlichkeitSensitive to light; Sensitivity to humidity
Spezifische Drehung [α][α]20/D +15.5±0.5°, c = 5% in 5 M HCl
Siedepunkt (°C)122-134 °C
Schmelzpunkt (°C)270-340 °C (decomposition)
Molekulargewicht131.170 g/mol
XLogP3-1.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass131.095 Da
Monoisotopic Mass131.095 Da
Topological Polar Surface Area63.300 Ų
Heavy Atom Count9
Formal Charge0
Complexity101.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
FAQs und Artikel
GMP
From Spec to Bench: Understanding and Using USP Grade Reagents
JP Grade Reagents Explained
For Cell Culture
List of Natural Amino Acids
Peptide Basics
β-Acyloxy Alkenyl Amides (AAAs): A New Approach to Amide Bond and Peptide Bond Construction Worth Attention
Silicon Reagent-Assisted Peptide Synthesis: Research Progress and Methodological Value of Peptide Bond Formation from Unprotected Substrates
From Analytical Instrument to Synthetic Platform: A New Strategy for Reconstructing Automated Flow Solid-Phase Peptide Synthesis with Standard Analytical HPLC
Reassessing Trimethylaluminum: Method Design and Experimental Value of One-Pot Peptide Elongation from Unprotected Amino Acids
Central–Peripheral Signaling Networks Regulated by Neuropeptides and the Integration of Energy Metabolism
Methods and Applications for the Determination of Amino Acid Content and Composition
Analysis of Hydrolyzed Pearl as a Cosmetic Raw Material: Preparation Process, Active Components, and Skincare Formulation Applications
Sources, Host-Regulatory Mechanisms, and Tumor-Immune Effects of Gut Microbiota-Derived Metabolites
Catalytic Mechanisms of the Aminotransferase Family and Regulation of Amino Acid Metabolism
Regulation of Aging by Dietary Restriction, Rapamycin, AKG, and Carglumic Acid
Citations of This Product
Lösungsrechner
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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View USP grade guide → View JP grade guide → View Moligand™ grade guide → View Ph.Eur. grade guide → View for Cell culture grade guide →

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