Lidocaine , CAS No.137-58-6

CAS: 137-58-6 Cat. No.: L1371946-GMP Molecular Weight: 234.34 Beilstein Registry Number: 12(4)2538 EC Number: 205-302-8

Storage

Room temperature

Shipped In

Normal

Overview

Lidocaine (GMP) is Lidocaine produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Lidocaine inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia.

Specifications

Storage

Room temperature

Shipped In

Normal

Product Properties

• ALogP: 2.3

Names and Identifiers

• Canonical Smiles: CCN(CC)CC(=O)NC1=C(C=CC=C1C)C
• IUPAC Name: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
• InChIKey: NNJVILVZKWQKPM-UHFFFAOYSA-N
• INCHI: 1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
• Isomeric SMILES: CCN(CC)CC(=O)NC1=C(C=CC=C1C)C
• WGK Germany: 3
• RTECS: AN7525000
• Molecular Weight: 234.34
• Beilstein: 12(4)2538
• Reaxy-Rn: 2215784
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2215784&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Xylenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Xylenes
• Intermediate Tree Nodes: Not available
• Direct Parent: m-Xylenes
• Alternative Parents: Trialkylamines Propargyl-type 1,3-dipolar organic compounds Carboximidic acids Organopnictogen compounds Organooxygen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: M-xylene - Tertiary aliphatic amine - Tertiary amine - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidic acid derivative - Carboximidic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as m-xylenes. These are aromatic compounds that contain a m-xylene moiety, which is a monocyclic benzene carrying exactly two methyl groups at the 1- and 3-positions.
• External Descriptors: tertiary amino compound - monocarboxylic acid amide - benzenes

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Boil Point(°C): 182 °C/4 mmHg
• Melt Point(°C): 69 °C

References

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