Probable G-protein coupled receptor 139 (GPR139)

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  1. JNJ 63533054, Agonist of GPR139
    CAS: 1802326-66-4 EC Number: 110-689-0 Formula: C17H17ClN2O2 Molecular Weight: 316.78
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: J288738
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    IUPAC Name
    3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide
    SMILES
    CC(C1=CC=CC=C1)NC(=O)CNC(=O)C2=CC(=CC=C2)Cl
    InChIKey
    MWDVCHRYCKXEBY-LBPRGKRZSA-N
    InChI
    1S/C17H17ClN2O2/c1-12(13-6-3-2-4-7-13)20-16(21)11-19-17(22)14-8-5-9-15(18)10-14/h2-10,12H,11H2,1H3,(H,19,22)(H,20,21)/t12-/m0/s1
    Synonyms
    3-Chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide | (S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl)...
  2. L-Phenylalanine, Agonist of GPR139
    CAS: 63-91-2 EC Number: 200-568-1 Formula: C9H11NO2 Molecular Weight: 165.2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: P110424
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    IUPAC Name
    (2S)-2-amino-3-phenylpropanoic acid
    SMILES
    C1=CC=C(C=C1)CC(C(=O)O)N
    InChIKey
    COLNVLDHVKWLRT-QMMMGPOBSA-N
    InChI
    1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
    Synonyms
    NCIStruc2_000248 | PHENYLALANINE [VANDF] | Phenylalanine, L- | (-)-phenylalanine | Alanine, phenyl-, L- | beta-Phenyl...
  3. L-Tryptophan, Allosteric modulator of CaS receptor;Agonist of GPR139;Inhibitor of Proton-coupled Amino acid Transporter 1
    CAS: 73-22-3 EC Number: 200-795-6 Formula: C11H12N2O2 Molecular Weight: 204.23
    Solid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. USP ? United States Pharmacopeia grade — meets USP monograph specs for pharmaceutical use. Use for drug manufacturing, QC, and applications requiring US compendial compliance. JP ? Japanese Pharmacopoeia grade — conforms to JP monograph standards. Use for pharmaceutical products subject to Japanese regulatory requirements. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Ph.Eur. ? European Pharmacopoeia grade — conforms to Ph.Eur. monographs across EU member states. Use for pharmaceutical work needing European compendial compliance. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. ≥99%
    In Stock Item #: T118579
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    IUPAC Name
    (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
    SMILES
    C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
    InChIKey
    QIVBCDIJIAJPQS-VIFPVBQESA-N
    InChI
    1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
    Synonyms
    (S)-2-Amino-3-(3-indolyl)propionic acid | h-Trp-oh | L-Trytophan
  4. TC-O 9311
    CAS: 444932-31-4 PubChem CID: 3376937 Formula: C200H19N3O4 Molecular Weight: 365.38
    In Stock Item #: T287907
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    IUPAC Name
    1-[(3,5-dimethoxybenzoyl)amino]-3-naphthalen-1-ylurea
    SMILES
    COC1=CC(=CC(=C1)C(=O)NNC(=O)NC2=CC=CC3=CC=CC=C32)OC
    InChIKey
    KPTMSQHTGZMEFU-UHFFFAOYSA-N
    InChI
    1S/C20H19N3O4/c1-26-15-10-14(11-16(12-15)27-2)19(24)22-23-20(25)21-18-9-5-7-13-6-3-4-8-17(13)18/h3-12H,1-2H3,(H,22,24)(H2,21,23,25)
    Synonyms
    Z)-N'-((Z)-hydroxy(naphthalen-1-ylimino)methyl)-3,5-dimethoxybenzohydrazonic acid | 3,5-Dimethoxybenzoic acid 2-[(1-n...
  5. L-Phenylalanine
    CAS: 63-91-2 EC Number: 200-568-1 Formula: C9H11NO2 Molecular Weight: 165.2
    Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. USP ? United States Pharmacopeia grade — meets USP monograph specs for pharmaceutical use. Use for drug manufacturing, QC, and applications requiring US compendial compliance. JP ? Japanese Pharmacopoeia grade — conforms to JP monograph standards. Use for pharmaceutical products subject to Japanese regulatory requirements. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Ph.Eur. ? European Pharmacopoeia grade — conforms to Ph.Eur. monographs across EU member states. Use for pharmaceutical work needing European compendial compliance. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. ≥98.5%
    In Stock Item #: P110425
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    Technical Identifiers
    IUPAC Name
    (2S)-2-amino-3-phenylpropanoic acid
    SMILES
    C1=CC=C(C=C1)CC(C(=O)O)N
    InChIKey
    COLNVLDHVKWLRT-QMMMGPOBSA-N
    InChI
    1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
    Synonyms
    phenylalanine | (2S)-2-amino-3-phenylpropanoic acid | (S)-2-Amino-3-phenylpropionic acid | 3-Phenyl-L-alanine | (S)-2...
  6. L-Tryptophan
    CAS: 73-22-3 EC Number: 200-795-6 Formula: C11H12N2O2 Molecular Weight: 204.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: T103480
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    Technical Identifiers
    IUPAC Name
    (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
    SMILES
    C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
    InChIKey
    QIVBCDIJIAJPQS-VIFPVBQESA-N
    InChI
    1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
    Synonyms
    TRP | TRYPTOPHAN [USP MONOGRAPH] | Tryptophanum | Tryptan | 1H-Indole-3-alanine | L-Trp | TRYPTOPHAN [INCI] | (S)-2-A...
  7. JNJ 63533054, Agonist of GPR139
    CAS: 1802326-66-4 EC Number: 110-689-0 Formula: C17H17ClN2O2 Molecular Weight: 316.78
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: J422208
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    Technical Identifiers
    IUPAC Name
    3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide
    SMILES
    CC(C1=CC=CC=C1)NC(=O)CNC(=O)C2=CC(=CC=C2)Cl
    InChIKey
    MWDVCHRYCKXEBY-LBPRGKRZSA-N
    InChI
    1S/C17H17ClN2O2/c1-12(13-6-3-2-4-7-13)20-16(21)11-19-17(22)14-8-5-9-15(18)10-14/h2-10,12H,11H2,1H3,(H,19,22)(H,20,21)/t12-/m0/s1
    Synonyms
    3-Chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide;(S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl)be...
  8. L-Tryptophan
    CAS: 73-22-3 EC Number: 200-795-6 Formula: C11H12N2O2 Molecular Weight: 204.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: L425719
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    Technical Identifiers
    IUPAC Name
    (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
    SMILES
    C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
    InChIKey
    QIVBCDIJIAJPQS-VIFPVBQESA-N
    InChI
    1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
    Synonyms
    L-tryptophan|tryptophan|73-22-3|L-Tryptophane|h-Trp-oh|(S)-Tryptophan|Tryptophane|trofan|tryptacin|Ardeytropin|Optima...
  9. TAK-041, Agonist of GPR139
    CAS: 1929519-13-0 Formula: C18H15F3N4O3 Molecular Weight: 392.33
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T614307
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    IUPAC Name
    2-(4-oxo-1,2,3-benzotriazin-3-yl)-N-[(1S)-1-[4-(trifluoromethoxy)phenyl]ethyl]acetamide
    SMILES
    CC(C1=CC=C(C=C1)OC(F)(F)F)NC(=O)CN2C(=O)C3=CC=CC=C3N=N2
    InChIKey
    JZGLECLGVQRPPI-NSHDSACASA-N
    InChI
    1S/C18H15F3N4O3/c1-11(12-6-8-13(9-7-12)28-18(19,20)21)22-16(26)10-25-17(27)14-4-2-3-5-15(14)23-24-25/h2-9,11H,10H2,1H3,(H,22,26)/t11-/m0/s1
    Synonyms
    (S)-2-(4-Oxobenzo[d][1,2,3]triazin-3(4H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide | Zelatriazin
  10. LP-360924, Agonist of GPR139
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: L611577
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    IUPAC Name
    6-methoxy-N2-(3-methoxypropyl)-N4-{4-phenyl-5-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]-1,3-thiazol-2-yl}-1,3,5-triazine-2,4-diamine
    SMILES
    COCCCNc1nc(Nc2nc(c(s2)C(=O)N2CCN(CC2)c2ncccn2)c2ccccc2)nc(n1)OC
    InChIKey
    OIRCJRUZRVLDFA-UHFFFAOYSA-N
    InChI
    1S/C26H30N10O3S/c1-38-17-7-12-27-22-31-23(33-25(32-22)39-2)34-26-30-19(18-8-4-3-5-9-18)20(40-26)21(37)35-13-15-36(16-14-35)24-28-10-6-11-29-24/h3-6,8-show more
  11. L-Tryptophan
    CAS: 73-22-3 EC Number: 200-795-6 Formula: C11H12N2O2 Molecular Weight: 204.23
    Solid UltraBio™ ? UltraBio™ — Aladdin's line for molecular-biology applications. Use for nuclease-free, high-consistency reagents across molecular workflows. ≥99.5%(NT)
    Out of Stock Item #: L755707
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
    SMILES
    C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
    InChIKey
    QIVBCDIJIAJPQS-VIFPVBQESA-N
    InChI
    1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
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