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Gamma-aminobutyric acid receptor subunit alpha-2 (GABRA2)

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  1. MRK 016, Allosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α5 subunit
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    MRK 016, Allosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α5 subunit
    CAS: 342652-67-9 Formula: C17H20N8O2 Molecular Weight: 368.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    Out of Stock Item #: M286670
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    IUPAC Name
    3-[3-tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)methoxy]pyrazolo[1,5-d][1,2,4]triazin-7-yl]-5-methyl-1,2-oxazole
    SMILES
    CC1=CC(=NO1)C2=NN=CC3=C(C(=NN32)OCC4=NC=NN4C)C(C)(C)C
    InChIKey
    QYSYOGCIDRANAR-UHFFFAOYSA-N
    InChI
    1S/C17H20N8O2/c1-10-6-11(23-27-10)15-21-19-7-12-14(17(2,3)4)16(22-25(12)15)26-8-13-18-9-20-24(13)5/h6-7,9H,8H2,1-5H3
    Synonyms
    MS-25900 | NSC51108 | GTPL4257 | BCP18257 | DL-Isoleucine, cell culture tested | UNII-TXZ4DVJ9MF | 3-tert-butyl-7-(5-...
  2. Ethyl β-carboline-3-carboxylate (β-CCE)
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    Ethyl β-carboline-3-carboxylate (β-CCE)
    CAS: 74214-62-3 EC Number: 624-676-7 Formula: C14H12N2O2 Molecular Weight: 240.3
    ≥97%
    In Stock Item #: E344904
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    IUPAC Name
    ethyl 9H-pyrido[3,4-b]indole-3-carboxylate
    SMILES
    CCOC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2
    InChIKey
    KOVRZNUMIKACTB-UHFFFAOYSA-N
    InChI
    1S/C14H12N2O2/c1-2-18-14(17)12-7-10-9-5-3-4-6-11(9)16-13(10)8-15-12/h3-8,16H,2H2,1H3
    Synonyms
    beta-carbolin-3-carboxylic acid ethyl ester | beta-CCE | ETHYL .BETA.-CARBOLINE-3-CARBOXYLATE | Ethyl beta-carboline-...
  3. TB 21007
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    TB 21007
    CAS: 207306-50-1 PubChem CID: 6918633 Formula: C15H17NO2S3 Molecular Weight: 339.5
    ≥99%(HPLC)
    Out of Stock Item #: T288798
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    IUPAC Name
    3-(2-hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one
    SMILES
    CC1(CC2=C(SC(=C2C(=O)C1)SCCO)C3=NC=CS3)C
    InChIKey
    QILRYFCEXLFIDS-UHFFFAOYSA-N
    InChI
    1S/C15H17NO2S3/c1-15(2)7-9-11(10(18)8-15)14(20-6-4-17)21-12(9)13-16-3-5-19-13/h3,5,17H,4,6-8H2,1-2H3
    Synonyms
    UNII-VL2NQQ83RN | 6,7-Dihydro-3-((2-hydroxyethyl)thio)-6,6-dimethyl-1-(2-thiazolyl)benzo(C)thiophen-4(5H)-one | Benzo...
  4. Isonipecotic acid - Moligand™, ≥98% CAS No(498-94-2) by Aladdin Scientific
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    Isonipecotic acid, Agonist of GABA A receptor α1 subunit;Agonist of GABA A receptor α2 subunit;Agonist of GABA A receptor α3 subunit;Agonist of GABA A receptor α4 subunit;Agonist of GABA A receptor α5 subunit;Agonist of GABA A receptor α6 subunit;Antagonist of GABA A recept
    CAS: 498-94-2 EC Number: 207-872-3 Formula: C6H11NO2 Molecular Weight: 129.16
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: I109586
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    IUPAC Name
    piperidine-4-carboxylic acid
    SMILES
    C1CNCCC1C(=O)O
    InChIKey
    SRJOCJYGOFTFLH-UHFFFAOYSA-N
    InChI
    1S/C6H11NO2/c8-6(9)5-1-3-7-4-2-5/h5,7H,1-4H2,(H,8,9)
    Synonyms
    Acide piperidine-carboxylique-4 | EINECS 207-872-3 | Isonipecotic acid | iso-nipecotic acid | NCGC00015573-03 | SR-01...
  5. 1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one
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    1,3-Dihydro-5-phenyl-1,4-benzodiazepin-2-one
    CAS: 2898-08-0 EC Number: 220-781-3 Formula: C15H12N2O Molecular Weight: 236.27
    Solid ≥97%
    In Stock Item #: D183460
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    IUPAC Name
    5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
    SMILES
    C1C(=O)NC2=CC=CC=C2C(=N1)C3=CC=CC=C3
    InChIKey
    IVUAAOBNUNMJQC-UHFFFAOYSA-N
    InChI
    1S/C15H12N2O/c18-14-10-16-15(11-6-2-1-3-7-11)12-8-4-5-9-13(12)17-14/h1-9H,10H2,(H,17,18)
    Synonyms
    5-PHENYL-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE | 2-Butanone, 3-methylsulfonyl-, O-(N-methylcarbamoyl)oxime | CCG-244429 ...
  6. AZD-7325, Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Antagonist of MT 1 receptor
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    AZD-7325, Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Antagonist of MT 1 receptor
    CAS: 942437-37-8 EC Number: 935-772-6 Formula: C19H19FN4O2 Molecular Weight: 354.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A412213
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    IUPAC Name
    4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
    SMILES
    CCCNC(=O)C1=NN=C2C(=C1N)C=CC=C2C3=C(C=CC=C3F)OC
    InChIKey
    KYDURMHFWXCKMW-UHFFFAOYSA-N
    InChI
    1S/C19H19FN4O2/c1-3-10-22-19(25)18-16(21)12-7-4-6-11(17(12)23-24-18)15-13(20)8-5-9-14(15)26-2/h4-9H,3,10H2,1-2H3,(H2,21,23)(H,22,25)
    Synonyms
    AKOS037649295 | Q27074785 | SB17497 | D81581 | DB13994 | HY-111052 | KYDURMHFWXCKMW-UHFFFAOYSA-N | UNII-KNM216XOUH | ...
  7. CL 218872
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    CL 218872
    CAS: 66548-69-4 EC Number: 636-288-5 Formula: C13H9F3N4 Molecular Weight: 278.24
    ≥98%(HPLC)
    In Stock Item #: C288598
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    IUPAC Name
    3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine
    SMILES
    CC1=NN=C2N1N=C(C=C2)C3=CC(=CC=C3)C(F)(F)F
    InChIKey
    GUOQUXNJZHGPQF-UHFFFAOYSA-N
    InChI
    1S/C13H9F3N4/c1-8-17-18-12-6-5-11(19-20(8)12)9-3-2-4-10(7-9)13(14,15)16/h2-7H,1H3
    Synonyms
    UNII-O7GR5XL5B5 | AC-15943 | NCGC00025269-01 | 1,2,4-Triazolo[4,3-b]pyridazine, 3-methyl-6-[3-(trifluoromethyl)phenyl...
  8. Isonipecotic acid, Agonist of GABA A receptor α1 subunit;Agonist of GABA A receptor α2 subunit;Agonist of GABA A receptor α3 subunit;Agonist of GABA A receptor α4 subunit;Agonist of GABA A receptor α5 subunit;Agonist of GABA A receptor α6 subunit;Antagonist of GABA A recept
    Wish List Compare
    Isonipecotic acid, Agonist of GABA A receptor α1 subunit;Agonist of GABA A receptor α2 subunit;Agonist of GABA A receptor α3 subunit;Agonist of GABA A receptor α4 subunit;Agonist of GABA A receptor α5 subunit;Agonist of GABA A receptor α6 subunit;Antagonist of GABA A recept
    CAS: 498-94-2 EC Number: 207-872-3 Formula: C6H11NO2 Molecular Weight: 129.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in Water
    Out of Stock Item #: I424295
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    Technical Identifiers
    IUPAC Name
    piperidine-4-carboxylic acid
    SMILES
    C1CNCCC1C(=O)O
    InChIKey
    SRJOCJYGOFTFLH-UHFFFAOYSA-N
    InChI
    1S/C6H11NO2/c8-6(9)5-1-3-7-4-2-5/h5,7H,1-4H2,(H,8,9)
    Synonyms
    Acide piperidine-carboxylique-4 | EINECS 207-872-3 | Isonipecotic acid | iso-nipecotic acid | NCGC00015573-03 | SR-01...
  9. ONO-8590580, Allosteric modulator of GABA A receptor α5 subunit
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    ONO-8590580, Allosteric modulator of GABA A receptor α5 subunit
    CAS: 1802661-73-9 Formula: C21H21FN6 Molecular Weight: 376.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: O412143
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    IUPAC Name
    3-(cyclopropylmethyl)-6-fluoro-7-methyl-N-[5-(1-methylimidazol-4-yl)pyridin-2-yl]benzimidazol-5-amine
    SMILES
    CC1=C(C(=CC2=C1N=CN2CC3CC3)NC4=NC=C(C=C4)C5=CN(C=N5)C)F
    InChIKey
    INGJMHPGMVUEKY-UHFFFAOYSA-N
    InChI
    1S/C21H21FN6/c1-13-20(22)16(7-18-21(13)25-12-28(18)9-14-3-4-14)26-19-6-5-15(8-23-19)17-10-27(2)11-24-17/h5-8,10-12,14H,3-4,9H2,1-2H3,(H,23,26)
    Synonyms
    CHEMBL4581355 | CID 118278442 | 3-(cyclopropylmethyl)-6-fluoro-7-methyl-N-[5-(1-methylimidazol-4-yl)pyridin-2-yl]benz...
  10. α5IA, Allosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α5 subunit
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    α5IA, Allosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α5 subunit
    CAS: 215874-86-5 Formula: C17H14N8O2 Molecular Weight: 362.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: I346768
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    Technical Identifiers
    IUPAC Name
    5-methyl-3-[6-[(1-methyltriazol-4-yl)methoxy]-[1,2,4]triazolo[3,4-a]phthalazin-3-yl]-1,2-oxazole
    SMILES
    CC1=CC(=NO1)C2=NN=C3N2N=C(C4=CC=CC=C43)OCC5=CN(N=N5)C
    InChIKey
    NZMJFRXKGUCYNP-UHFFFAOYSA-N
    InChI
    1S/C17H14N8O2/c1-10-7-14(22-27-10)16-20-19-15-12-5-3-4-6-13(12)17(21-25(15)16)26-9-11-8-24(2)23-18-11/h3-8H,9H2,1-2H3
    Synonyms
    AM85665 | J-014159 | L-822179 | UNII-1M7NI1A92L | .ALPHA. 5IA | 3-(5-Methyl-1,2-oxazol-3-yl)-6-[(1-methyl-1H-1,2,3-tr...
  11. no_selection
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    [³H]RY80, GABA A receptor α5 subunit
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: H614225
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    IUPAC Name
    ethyl 8-ethynyl-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
    SMILES
    CCOC(=O)c1ncn2c1CN(C)C(=O)c1c2ccc(c1)C#C
    InChIKey
    WDTNKNNGHGOKBH-UHFFFAOYSA-N
    InChI
    1S/C17H15N3O3/c1-4-11-6-7-13-12(8-11)16(21)19(3)9-14-15(17(22)23-5-2)18-10-20(13)14/h1,6-8,10H,5,9H2,2-3H3
  12. no_selection
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    Basmisanil, Allosteric modulator of GABA A receptor α5 subunit
    CAS: 1159600-41-5 PubChem CID: 57336276 Formula: C21H20FN3O5S Molecular Weight: 445.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B607930
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    Technical Identifiers
    IUPAC Name
    (1,1-dioxo-1,4-thiazinan-4-yl)-[6-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]pyridin-3-yl]methanone
    SMILES
    CC1=C(C(=NO1)C2=CC=C(C=C2)F)COC3=NC=C(C=C3)C(=O)N4CCS(=O)(=O)CC4
    InChIKey
    VCGRFBXVSFAGGA-UHFFFAOYSA-N
    InChI
    1S/C21H20FN3O5S/c1-14-18(20(24-30-14)15-2-5-17(22)6-3-15)13-29-19-7-4-16(12-23-19)21(26)25-8-10-31(27,28)11-9-25/h2-7,12H,8-11,13H2,1H3
    Synonyms
    DB11877 | EX-A1272 | (1,1-dioxo-1,4-thiazinan-4-yl)-[6-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]pyridin-...
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