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1-phosphatidylinositol 3-phosphate 5-kinase (PIKFYVE)

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  1. Vacuolin-1
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    Vacuolin-1
    CAS: 351986-85-1 EC Number: 636-870-9 PubChem CID: 9661141 Formula: C26H24IN7O Molecular Weight: 577.42
    ≥95%
    In Stock Item #: V336926
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    Technical Identifiers
    IUPAC Name
    2-N-[(E)-(3-iodophenyl)methylideneamino]-6-morpholin-4-yl-4-N,4-N-diphenyl-1,3,5-triazine-2,4-diamine
    SMILES
    C1COCCN1C2=NC(=NC(=N2)NN=CC3=CC(=CC=C3)I)N(C4=CC=CC=C4)C5=CC=CC=C5
    InChIKey
    JMEJTSRAQUFNOP-TURZUDJPSA-N
    InChI
    1S/C26H24IN7O/c27-21-9-7-8-20(18-21)19-28-32-24-29-25(33-14-16-35-17-15-33)31-26(30-24)34(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-13,18-19H,14-17H2,(H,show more
    Synonyms
    4-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-6-(morpholin-4-yl)-N,N-diphenyl-1,3,5-triazin-2-amine | BDBM50595937 | J-019...
  2. Vacuolin-1
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    Vacuolin-1
    CAS: 351986-85-1 EC Number: 636-870-9 PubChem CID: 9661141 Formula: C26H24IN7O Molecular Weight: 577.42
    10mM in DMSO
    In Stock Item #: V423569
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    Technical Identifiers
    IUPAC Name
    2-N-[(E)-(3-iodophenyl)methylideneamino]-6-morpholin-4-yl-4-N,4-N-diphenyl-1,3,5-triazine-2,4-diamine
    SMILES
    C1COCCN1C2=NC(=NC(=N2)NN=CC3=CC(=CC=C3)I)N(C4=CC=CC=C4)C5=CC=CC=C5
    InChIKey
    JMEJTSRAQUFNOP-TURZUDJPSA-N
    InChI
    1S/C26H24IN7O/c27-21-9-7-8-20(18-21)19-28-32-24-29-25(33-14-16-35-17-15-33)31-26(30-24)34(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-13,18-19H,14-17H2,(H,show more
    Synonyms
    4-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-6-(morpholin-4-yl)-N,N-diphenyl-1,3,5-triazin-2-amine | BDBM50595937 | J-019...
  3. YM201636
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    YM201636
    CAS: 371942-69-7 PubChem CID: 9956222 Formula: C25H21N7O3 Molecular Weight: 467.48
    10mM in DMSO
    In Stock Item #: Y409040
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    Technical Identifiers
    Synonyms
    3-Pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-
  4. YM201636
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    YM201636
    CAS: 371942-69-7 PubChem CID: 9956222 Formula: C25H21N7O3 Molecular Weight: 467.48
    ≥96%
    In Stock Item #: Y126759
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    Technical Identifiers
    IUPAC Name
    6-amino-N-[3-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenyl]pyridine-3-carboxamide
    SMILES
    C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N
    InChIKey
    YBPIBGNBHHGLEB-UHFFFAOYSA-N
    InChI
    1S/C25H21N7O3/c26-19-7-6-16(14-28-19)24(33)29-17-4-1-3-15(13-17)22-30-20-18-5-2-8-27-25(18)35-21(20)23(31-22)32-9-11-34-12-10-32/h1-8,13-14H,9-12H2,(Hshow more
    Synonyms
    AKOS027250783 | HY-13228 | SW218129-2 | 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phe...
  5. no_selection
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    11-(3-(Dimethylamino)prop-1-yn-1-yl)-5,6,7,8-tetrahydropyrimido[4′,5′:3,4]cyclohepta[1,2-b]indol-2-amine, Inhibitor of myosin light chain kinase family member 4;Inhibitor of phosphoinositide kinase; FYVE-type zinc finger containing
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: D608800
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    IUPAC Name
    11-(3-(Dimethylamino)prop-1-yn-1-yl)-5,6,7,8-tetrahydropyrimido[4′,5′:3,4]cyclohepta[1,2-b]indol-2-amine
    SMILES
    Nc1ncc2CCCc3c(c2n1)c1c([nH]3)ccc(c1)C#CCN(C)C
    InChIKey
    DORZPJWJOBMQKC-UHFFFAOYSA-N
    InChI
    1S/C20H21N5/c1-25(2)10-4-5-13-8-9-16-15(11-13)18-17(23-16)7-3-6-14-12-22-20(21)24-19(14)18/h8-9,11-12,23H,3,6-7,10H2,1-2H3,(H2,21,22,24)
    Synonyms
    compound 17
  6. no_selection
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    AMG28, Inhibitor of mitogen-activated protein kinase kinase kinase 14;Inhibitor of p21 (RAC1) activated kinase 4;Inhibitor of p21 (RAC1) activated kinase 5;Inhibitor of p21 (RAC1) activated kinase 6;Inhibitor of phosphoinositide kinase; FYVE-type zinc finger con
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: A607602
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    Technical Identifiers
    SMILES
    CC(C)(C#Cc1cc2c(cc1)[nH]c1c2c2c(CCC1)cnc(n2)N)O
    InChIKey
    DGLFSNZWRYADFC-UHFFFAOYSA-N
    InChI
    1S/C20H20N4O/c1-20(2,25)9-8-12-6-7-15-14(10-12)17-16(23-15)5-3-4-13-11-22-19(21)24-18(13)17/h6-7,10-11,23,25H,3-5H2,1-2H3,(H2,21,22,24)
    Synonyms
    example 240;inhibitor 3
  7. no_selection
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    YL5084, Inhibitor of mitogen-activated protein kinase 8;Inhibitor of mitogen-activated protein kinase 9
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: Y614917
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    IUPAC Name
    (E)-4-(dimethylamino)-N-[4-[(3S,4S)-3-methyl-4-[[4-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyrimidin-2-yl]amino]pyrrolidine-1-carbonyl]phenyl]but-2-enamishow more
    SMILES
    C[C@H]1CN(C(C2=CC=C(C=C2)NC(/C=C/CN(C)C)=O)=O)C[C@H]1NC3=NC=CC(C4=C5C=CC=CN5N=C4C6=CC=CC=C6)=N3
    InChIKey
    FVONQZQMUHLATI-PIAHHGHBSA-N
    InChI
    1S/C35H36N8O2/c1-24-22-42(34(45)26-14-16-27(17-15-26)37-31(44)13-9-20-41(2)3)23-29(24)39-35-36-19-18-28(38-35)32-30-12-7-8-21-43(30)40-33(32)25-10-5-4show more
    Synonyms
    YL-5084
  9. MOMIPP - 10mM in DMSO CAS No(1363421-46-8) by Aladdin Scientific
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    MOMIPP
    CAS: 1363421-46-8 Formula: C18H16N2O2 Molecular Weight: 292.33
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: M654628
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  10. MOMIPP - ≥99% CAS No(1363421-46-8) by Aladdin Scientific
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    MOMIPP
    CAS: 1363421-46-8 Formula: C18H16N2O2 Molecular Weight: 292.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: M646552
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    Technical Identifiers
    IUPAC Name
    (E)-3-(5-methoxy-2-methyl-1H-indol-3-yl)-1-pyridin-4-ylprop-2-en-1-one
    SMILES
    CC1=C(C2=C(N1)C=CC(=C2)OC)C=CC(=O)C3=CC=NC=C3
    InChIKey
    UPJCYXIOWHZRLU-GQCTYLIASA-N
    InChI
    1S/C18H16N2O2/c1-12-15(4-6-18(21)13-7-9-19-10-8-13)16-11-14(22-2)3-5-17(16)20-12/h3-11,20H,1-2H3/b6-4+
  11. APY0201
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    APY0201
    CAS: 1232221-74-7 PubChem CID: 56927660 Formula: C23H23N7O Molecular Weight: 413.5
    ≥98%
    Out of Stock Item #: A646803
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    Technical Identifiers
    IUPAC Name
    N-[(E)-(3-methylphenyl)methylideneamino]-7-morpholin-4-yl-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-5-amine
    SMILES
    CC1=CC(=CC=C1)C=NNC2=NC3=CC(=NN3C(=C2)N4CCOCC4)C5=CC=NC=C5
    InChIKey
    RFZQYGBLRIKROZ-PCLIKHOPSA-N
    InChI
    1S/C23H23N7O/c1-17-3-2-4-18(13-17)16-25-27-21-15-23(29-9-11-31-12-10-29)30-22(26-21)14-20(28-30)19-5-7-24-8-6-19/h2-8,13-16H,9-12H2,1H3,(H,26,27)/b25-show more
  12. CID 134451950
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    CID 134451950
    CAS: 2058075-45-7 Formula: C31H29N7O2 Molecular Weight: 531.600
    ≥99%
    Out of Stock Item #: C954977
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    Technical Identifiers
    IUPAC Name
    4-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-[[6-(1H-indol-3-yl)pyrimidin-4-yl]amino]phenyl]benzamide
    SMILES
    CN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=NC(=C3)C4=CNC5=CC=CC=C54
    InChIKey
    MJJJRRMQCUUKEO-IZZDOVSWSA-N
    InChI
    1S/C31H29N7O2/c1-38(2)16-6-11-30(39)36-22-14-12-21(13-15-22)31(40)37-24-8-5-7-23(17-24)35-29-18-28(33-20-34-29)26-19-32-27-10-4-3-9-25(26)27/h3-15,17-show more
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