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Nuak family snf1-like kinase 2 (NUAK2)

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  1. Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitor
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    Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitor
    CAS: 111358-88-4 Formula: C26H21N3O4 Molecular Weight: 439.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: L275009
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    IUPAC Name
    (15S,16S,18R)-16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,1show more
    SMILES
    CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
    InChIKey
    UIARLYUEJFELEN-LROUJFHJSA-N
    InChI
    1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12Hshow more
    Synonyms
    SPM-924 | (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanod...
  2. GSK461364, Serine/threonine-protein kinase PLK1 inhibitor
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    GSK461364, Serine/threonine-protein kinase PLK1 inhibitor
    CAS: 929095-18-1 Formula: C27H28F3N5O2S Molecular Weight: 543.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G127124
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    IUPAC Name
    5-[6-[(4-methylpiperazin-1-yl)methyl]benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide
    SMILES
    CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N
    InChIKey
    ZHJGWYRLJUCMRT-QGZVFWFLSA-N
    InChI
    1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28,29)30)37-23-14-24(38-25(23)26(31)36)35-16-32-21-8-7-18(13-22(21)35)15-34-11-9-33(2)10-12-34/h3-8,13-14,1show more
    Synonyms
    CCG-264940 | GTPL5684 | SW220052-1 | AC-23167 | GSK 461364 | 5-[6-[(4-Methyl-1-piperazinyl)methyl]-1h-benzimidazol-1-...
  3. WZ 4003, Inhibitor of NUAK family kinase 1;Inhibitor of NUAK family; SNF1-like kinase; 2
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    WZ 4003, Inhibitor of NUAK family kinase 1;Inhibitor of NUAK family; SNF1-like kinase; 2
    CAS: 1214265-58-3 EC Number: 110-219-4 PubChem CID: 72200024 Formula: C25H29ClN6O3 Molecular Weight: 497
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: W275066
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    IUPAC Name
    N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide
    SMILES
    CCC(=O)NC1=CC(=CC=C1)OC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC
    InChIKey
    SDGJBAUIGHSMRI-UHFFFAOYSA-N
    InChI
    1S/C25H29ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h5-9,14-16H,4,10-13H2,1-3show more
    Synonyms
    BCP09218 | CCG-264737 | WZ 4003 | C25H29ClN6O3 | WZ4003, >=98% (HPLC) | NCGC00386309-05 | s7317 | 1214265-58-3 | N-(3...
  4. HTH-01-015, Inhibitor of NUAK family kinase 1
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    HTH-01-015, Inhibitor of NUAK family kinase 1
    CAS: 1613724-42-7 Formula: C26H28N8O Molecular Weight: 468.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: H286770
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    IUPAC Name
    2,7,9-trimethyl-5-[(1-piperidin-4-ylpyrazol-4-yl)amino]-2,4,6,9-tetrazatetracyclo[9.8.0.03,8.013,18]nonadeca-1(19),3,5,7,11,13,15,17-octaen-10-one
    SMILES
    CC1=C2C(=NC(=N1)NC3=CN(N=C3)C4CCNCC4)N(C5=CC6=CC=CC=C6C=C5C(=O)N2C)C
    InChIKey
    CHSDJDLAKKAWCI-UHFFFAOYSA-N
    InChI
    1S/C26H28N8O/c1-16-23-24(31-26(29-16)30-19-14-28-34(15-19)20-8-10-27-11-9-20)32(2)22-13-18-7-5-4-6-17(18)12-21(22)25(35)33(23)3/h4-7,12-15,20,27H,8-11show more
    Synonyms
    5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diaze...
  5. WZ4002, Inhibitor of BLK proto-oncogene; Src family tyrosine kinase;Inhibitor of Bruton tyrosine kinase;Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 4;Inhibitor of IL2 inducible T cell kinase;Inhibitor of NUAK family
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    WZ4002, Inhibitor of BLK proto-oncogene; Src family tyrosine kinase;Inhibitor of Bruton tyrosine kinase;Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 4;Inhibitor of IL2 inducible T cell kinase;Inhibitor of NUAK family
    CAS: 1213269-23-8 PubChem CID: 44607530 Formula: C25H27ClN6O3 Molecular Weight: 494.97
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: W127713
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    IUPAC Name
    N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
    SMILES
    CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl)OC
    InChIKey
    ITTRLTNMFYIYPA-UHFFFAOYSA-N
    InChI
    1S/C25H27ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h4-9,14-16H,1,10-13H2,2-3show more
    Synonyms
    NCGC00263144-02 | CCG-264847 | s1173 | WZ 4002 | N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimi...
  6. Brivanib Alaninate (BMS-582664) - Moligand™, ≥95% CAS No(649735-63-7) by Aladdin Scientific
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    Brivanib Alaninate (BMS-582664), Vascular endothelial growth factor receptor inhibitor
    CAS: 649735-63-7 EC Number: 639-686-7 Formula: C22H24FN5O4 Molecular Weight: 441.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: B129764
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    IUPAC Name
    [(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate
    SMILES
    CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)OC(=O)C(C)N)C
    InChIKey
    LTEJRLHKIYCEOX-OCCSQVGLSA-N
    InChI
    1S/C22H24FN5O4/c1-11-7-15-16(27-11)5-6-17(19(15)23)32-21-20-13(3)18(8-28(20)26-10-25-21)30-9-12(2)31-22(29)14(4)24/h5-8,10,12,14,27H,9,24H2,1-4H3/t12-show more
    Synonyms
    BMS582664 | alaninati brivanibum | Brivanib alaninate (JAN/USAN/INN) | D08878 | 4-methanesulfonyl-piperazine | DB1186...
  7. Brivanib Alaninate (BMS-582664), Vascular endothelial growth factor receptor inhibitor
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    Brivanib Alaninate (BMS-582664), Vascular endothelial growth factor receptor inhibitor
    CAS: 649735-63-7 EC Number: 639-686-7 Formula: C22H24FN5O4 Molecular Weight: 441.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: B408875
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    Synonyms
    (S)-((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-yl) 2-aminop...
  8. CYC116, Vascular endothelial growth factor receptor 2 inhibitor
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    CYC116, Vascular endothelial growth factor receptor 2 inhibitor
    CAS: 693228-63-6 Formula: C18H20N6OS Molecular Weight: 368.46
    ≥98%
    In Stock Item #: C126929
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    IUPAC Name
    4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine
    SMILES
    CC1=C(SC(=N1)N)C2=NC(=NC=C2)NC3=CC=C(C=C3)N4CCOCC4
    InChIKey
    GPSZYOIFQZPWEJ-UHFFFAOYSA-N
    InChI
    1S/C18H20N6OS/c1-12-16(26-17(19)21-12)15-6-7-20-18(23-15)22-13-2-4-14(5-3-13)24-8-10-25-11-9-24/h2-7H,8-11H2,1H3,(H2,19,21)(H,20,22,23)
    Synonyms
    2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine, 5 | AC-32833 | NSC800082 | NSC-8000...
  10. G1T38 - Moligand™, 2mM in DMSO CAS No(1628256-23-4) by Aladdin Scientific
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    G1T38, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6
    CAS: 1628256-23-4 Formula: C26H34N8O Molecular Weight: 474.60
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    Out of Stock Item #: G421989
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    IUPAC Name
    4-[[5-(4-propan-2-ylpiperazin-1-yl)pyridin-2-yl]amino]spiro[1,3,5,11-tetrazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraene-13,1'-cyclohexane]-10-one
    SMILES
    CC(C)N1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6
    InChIKey
    YPJRHEKCFKOVRT-UHFFFAOYSA-N
    InChI
    1S/C26H34N8O/c1-18(2)32-10-12-33(13-11-32)20-6-7-22(27-16-20)30-25-28-15-19-14-21-24(35)29-17-26(8-4-3-5-9-26)34(21)23(19)31-25/h6-7,14-16,18H,3-5,8-1show more
    Synonyms
    G1T38; Lerociclib | 7',8'-Dihydro-2'-((5-(4-(1-methylethyl)-1-piperazinyl)-2-pyridinyl)amino)spiro(cyclohexane-1,9'(6...
  11. G1T38 - Moligand™, ≥99% CAS No(1628256-23-4) by Aladdin Scientific
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    Lerociclib(G1T38), Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6
    CAS: 1628256-23-4 Formula: C26H34N8O Molecular Weight: 474.60
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: G414063
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    Technical Identifiers
    IUPAC Name
    4-[[5-(4-propan-2-ylpiperazin-1-yl)pyridin-2-yl]amino]spiro[1,3,5,11-tetrazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraene-13,1'-cyclohexane]-10-one
    SMILES
    CC(C)N1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6
    InChIKey
    YPJRHEKCFKOVRT-UHFFFAOYSA-N
    InChI
    1S/C26H34N8O/c1-18(2)32-10-12-33(13-11-32)20-6-7-22(27-16-20)30-25-28-15-19-14-21-24(35)29-17-26(8-4-3-5-9-26)34(21)23(19)31-25/h6-7,14-16,18H,3-5,8-1show more
    Synonyms
    G1T38; Lerociclib | 7',8'-Dihydro-2'-((5-(4-(1-methylethyl)-1-piperazinyl)-2-pyridinyl)amino)spiro(cyclohexane-1,9'(6...
  12. GSK461364, Serine/threonine-protein kinase PLK1 inhibitor
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    GSK461364, Serine/threonine-protein kinase PLK1 inhibitor
    CAS: 929095-18-1 Formula: C27H28F3N5O2S Molecular Weight: 543.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G408291
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    Synonyms
    GSK461364A | 5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-((R)-1-(2-(trifluoromethyl)phenyl)etho...
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