Serine/threonine-protein kinase haspin (GSG2)

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  1. SGI-1776 free base, Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of histone H3 associated protein kinase;Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene;
    CAS: 1025065-69-3 PubChem CID: 24795070 Formula: C20H22F3N5O Molecular Weight: 405.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S126376
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    IUPAC Name
    N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine
    SMILES
    CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2
    InChIKey
    MHXGEROHKGDZGO-UHFFFAOYSA-N
    InChI
    1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26)
    Synonyms
    N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[2,1-f]pyridazin-6-amine | Imidazo[1,2-b]pyri...
  2. 5-Iodotubercidin
    CAS: 24386-93-4 EC Number: 194-755-4 Formula: C11H13IN4O4 Molecular Weight: 392.15
    In Stock Item #: L125077
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    IUPAC Name
    (2R,3R,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
    SMILES
    C1=C(C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)I
    InChIKey
    WHSIXKUPQCKWBY-IOSLPCCCSA-N
    InChI
    1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1
    Synonyms
    (2R,3R,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol | A848734 | BDBM503756...
  3. Harmol
    CAS: 487-03-6 Formula: C12H10N2O Molecular Weight: 198.23
    In Stock Item #: H156998
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    IUPAC Name
    1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one
    SMILES
    CC1=C2C(=C3C=CC(=O)C=C3N2)C=CN1
    InChIKey
    LBBJNGFCXDOYMQ-UHFFFAOYSA-N
    InChI
    1S/C12H10N2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12/h2-6,13-14H,1H3
    Synonyms
    DTXSID10960989 | TNP00139 | NCGC00017250-02 | EINECS 207-645-9 | 7-Hydroxyharman | A1-00784 | HY-107811 | KBio2_00081...
  4. LDN-192960
    CAS: 184582-62-5 Formula: C18H20N2O2S Molecular Weight: 328.43
    In Stock Item #: L168104
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    IUPAC Name
    3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine
    SMILES
    COC1=CC2=C(C=C1)N=C3C=CC(=CC3=C2SCCCN)OC
    InChIKey
    ZFOMCSNUEHMROO-UHFFFAOYSA-N
    InChI
    1S/C18H20N2O2S/c1-21-12-4-6-16-14(10-12)18(23-9-3-8-19)15-11-13(22-2)5-7-17(15)20-16/h4-7,10-11H,3,8-9,19H2,1-2H3
    Synonyms
    AC-35777 | HY-13455 | BCP06879 | EX-A4806 | MFCD02752814 | CCRIS 8174 | 3-[(2,7-Dimethoxyacridin-9-yl)thio]propan-1-a...
  5. 5-Iodotubercidin
    CAS: 24386-93-4 EC Number: 194-755-4 Formula: C11H13IN4O4 Molecular Weight: 392.15
    10mM in DMSO
    In Stock Item #: I422822
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    Technical Identifiers
    IUPAC Name
    (2R,3R,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
    SMILES
    C1=C(C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)I
    InChIKey
    WHSIXKUPQCKWBY-IOSLPCCCSA-N
    InChI
    1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1
    Synonyms
    (2R,3R,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol | A848734 | BDBM503756...
  6. CHR-6494
    CAS: 1333377-65-3 Formula: C16H16N6 Molecular Weight: 292.34
    Out of Stock Item #: C124894
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    IUPAC Name
    3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine
    SMILES
    CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1
    InChIKey
    CZZCAOGIEGXMBZ-UHFFFAOYSA-N
    InChI
    1S/C16H16N6/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20)
    Synonyms
    FT-0734501 | NCGC00370724-05 | 1333377-65-3 | CHR6494 | CHR-6494 | HY-15217 | BDBM50587785 | DTXSID90742629 | AKOS025...
  7. MELK-8a hydrochloride
    CAS: 1922153-17-0 Formula: C25H32N6O Molecular Weight: 432.6
    10mM in Water
    In Stock Item #: M422352
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    IUPAC Name
    1-methyl-4-[4-[4-[3-(piperidin-4-ylmethoxy)pyridin-4-yl]pyrazol-1-yl]phenyl]piperazine
    SMILES
    CN1CCN(CC1)C2=CC=C(C=C2)N3C=C(C=N3)C4=C(C=NC=C4)OCC5CCNCC5
    InChIKey
    BLFBSGVUERKSST-UHFFFAOYSA-N
    InChI
    1S/C25H32N6O/c1-29-12-14-30(15-13-29)22-2-4-23(5-3-22)31-18-21(16-28-31)24-8-11-27-17-25(24)32-19-20-6-9-26-10-7-20/h2-5,8,11,16-18,20,26H,6-7,9-10,12show more
    Synonyms
    MELK-8a HCl
  8. SGI-1776 free base, Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of histone H3 associated protein kinase;Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene;
    CAS: 1025065-69-3 PubChem CID: 24795070 Formula: C20H22F3N5O Molecular Weight: 405.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: S409214
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    Technical Identifiers
    Synonyms
    N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine
  9. INE963
    CAS: 2640567-43-5 PubChem CID: 156274257
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: I611060
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    IUPAC Name
    4-(aminomethyl)-1-{5-[2-methoxy-6-(propan-2-yl)pyridin-3-yl]imidazo[2,1-b][1,3,4]thiadiazol-2-yl}piperidin-4-ol
    SMILES
    COc1nc(ccc1c1cnc2sc(nn12)N1CCC(O)(CN)CC1)C(C)C
    InChIKey
    JYHSRMKXBAPFST-UHFFFAOYSA-N
    InChI
    1S/C19H26N6O2S/c1-12(2)14-5-4-13(16(22-14)27-3)15-10-21-17-25(15)23-18(28-17)24-8-6-19(26,11-20)7-9-24/h4-5,10,12,26H,6-9,11,20H2,1-3H3
    Synonyms
    MMV1582617;NVP-INE963
  10. Senexin B
    CAS: 1449228-40-3 PubChem CID: 71661259 Formula: C27H26N6O Molecular Weight: 450.5
    Out of Stock Item #: S1340731
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    IUPAC Name
    4-[2-[6-(4-methylpiperazine-1-carbonyl)naphthalen-2-yl]ethylamino]quinazoline-6-carbonitrile
    SMILES
    CN1CCN(CC1)C(=O)C2=CC3=C(C=C2)C=C(C=C3)CCNC4=NC=NC5=C4C=C(C=C5)C#N
    InChIKey
    VNADJTWHOAMTLY-UHFFFAOYSA-N
    InChI
    1S/C27H26N6O/c1-32-10-12-33(13-11-32)27(34)23-6-5-21-14-19(2-4-22(21)16-23)8-9-29-26-24-15-20(17-28)3-7-25(24)30-18-31-26/h2-7,14-16,18H,8-13H2,1H3,(Hshow more
  11. CDK8/19-IN-1
    CAS: 1818427-07-4 PubChem CID: 126511854
    Out of Stock Item #: C1424122
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    IUPAC Name
    8-[6-(2-methoxyethylcarbamoyl)pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
    SMILES
    COCCNC(=O)C1=NC=C(C=C1)OC2=C3C(=C(S2)C(=O)N)CCC4=C3SN=C4
    InChIKey
    NENJFZKQHYXRDQ-UHFFFAOYSA-N
    InChI
    1S/C19H18N4O4S2/c1-26-7-6-21-18(25)13-5-3-11(9-22-13)27-19-14-12(16(28-19)17(20)24)4-2-10-8-23-29-15(10)14/h3,5,8-9H,2,4,6-7H2,1H3,(H2,20,24)(H,21,25)
  12. CHR-6494
    CAS: 1333377-65-3 Formula: C16H16N6 Molecular Weight: 292.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: C1497828
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