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Serine/threonine-protein kinase tousled-like 2 (TLK2)

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  1. Toceranib, Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor alpha
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    Toceranib, Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor alpha
    CAS: 356068-94-5 EC Number: 973-271-4 PubChem CID: 5329106 Formula: C22H25FN4O2 Molecular Weight: 396.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T126745
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    IUPAC Name
    5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide
    SMILES
    CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O
    InChIKey
    SRSGVKWWVXWSJT-ATVHPVEESA-N
    InChI
    1S/C22H25FN4O2/c1-13-19(12-17-16-11-15(23)5-6-18(16)26-21(17)28)25-14(2)20(13)22(29)24-7-10-27-8-3-4-9-27/h5-6,11-12,25H,3-4,7-10H2,1-2H3,(H,24,29)(H,show more
    Synonyms
    Toceranib | BDBM4818 | AS-31877 | EINECS 206-730-8 | toceranibum | 5-[5-fluoro-2-oxo-1,2-dihydro-indol-(3Z)-ylideneme...
  2. N-Desethyl Sunitinib
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    N-Desethyl Sunitinib
    CAS: 356068-97-8 Formula: C20H23FN4O2 Molecular Weight: 370.42
    ≥96%
    Out of Stock Item #: N343433
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    IUPAC Name
    N-[2-(ethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
    SMILES
    CCNCCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
    InChIKey
    LIZNIAKSBJKPQC-GDNBJRDFSA-N
    InChI
    1S/C20H23FN4O2/c1-4-22-7-8-23-20(27)18-11(2)17(24-12(18)3)10-15-14-9-13(21)5-6-16(14)25-19(15)26/h5-6,9-10,22,24H,4,7-8H2,1-3H3,(H,23,27)(H,25,26)/b15show more
    Synonyms
    STL322510 | HY-10873 | SU-12662 | SU-11662 | UNII-42LJ35612R | 42LJ35612R | BDBM50564446 | EC 629-615-8 | SCHEMBL2115...
  3. Imidazolo-oxindole PKR inhibitor C16, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 2
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    Imidazolo-oxindole PKR inhibitor C16, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 2
    CAS: 608512-97-6 EC Number: 685-966-7 Formula: C13H8N4OS Molecular Weight: 268.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: I425038
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    IUPAC Name
    (8Z)-8-(1H-imidazol-5-ylmethylidene)-6H-pyrrolo[2,3-g][1,3]benzothiazol-7-one
    SMILES
    C1=CC2=C(C3=C1NC(=O)C3=CC4=CN=CN4)SC=N2
    InChIKey
    VFBGXTUGODTSPK-BAQGIRSFSA-N
    InChI
    1S/C13H8N4OS/c18-13-8(3-7-4-14-5-15-7)11-9(17-13)1-2-10-12(11)19-6-16-10/h1-6H,(H,14,15)(H,17,18)/b8-3-
    Synonyms
    PKR-IN-C16 | 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one | AKOS025147356 | SCHEMBL9...
  4. Imidazolo-oxindole PKR inhibitor C16, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 2
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    Imidazolo-oxindole PKR inhibitor C16, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 2
    CAS: 608512-97-6 EC Number: 685-966-7 Formula: C13H8N4OS Molecular Weight: 268.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C275080
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    Technical Identifiers
    IUPAC Name
    (8Z)-8-(1H-imidazol-5-ylmethylidene)-6H-pyrrolo[2,3-g][1,3]benzothiazol-7-one
    SMILES
    C1=CC2=C(C3=C1NC(=O)C3=CC4=CN=CN4)SC=N2
    InChIKey
    VFBGXTUGODTSPK-BAQGIRSFSA-N
    InChI
    1S/C13H8N4OS/c18-13-8(3-7-4-14-5-15-7)11-9(17-13)1-2-10-12(11)19-6-16-10/h1-6H,(H,14,15)(H,17,18)/b8-3-
    Synonyms
    PKR-IN-C16 | 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one | AKOS025147356 | SCHEMBL9...
  5. NMS-P118
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    NMS-P118
    CAS: 1262417-51-5 Formula: C20H24F3N3O2 Molecular Weight: 395.42
    10mM in DMSO
    In Stock Item #: N421100
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    IUPAC Name
    2-[1-(4,4-difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-1H-isoindole-4-carboxamide
    SMILES
    C1CC(CCC1N2CCC(CC2)N3CC4=C(C3=O)C(=CC(=C4)F)C(=O)N)(F)F
    InChIKey
    ARYVAQSYRLZVQD-UHFFFAOYSA-N
    InChI
    1S/C20H24F3N3O2/c21-13-9-12-11-26(19(28)17(12)16(10-13)18(24)27)15-3-7-25(8-4-15)14-1-5-20(22,23)6-2-14/h9-10,14-15H,1-8,11H2,(H2,24,27)
    Synonyms
    1H-Isoindole-4-carboxamide, 2-(1-(4,4-difluorocyclohexyl)-4-piperidinyl)-6-fluoro-2,3-dihydro-3-oxo- | AT32155 | EX-A...
  6. NMS-P118
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    NMS-P118
    CAS: 1262417-51-5 Formula: C20H24F3N3O2 Molecular Weight: 395.42
    ≥97%
    In Stock Item #: N413987
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[1-(4,4-difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-1H-isoindole-4-carboxamide
    SMILES
    C1CC(CCC1N2CCC(CC2)N3CC4=C(C3=O)C(=CC(=C4)F)C(=O)N)(F)F
    InChIKey
    ARYVAQSYRLZVQD-UHFFFAOYSA-N
    InChI
    1S/C20H24F3N3O2/c21-13-9-12-11-26(19(28)17(12)16(10-13)18(24)27)15-3-7-25(8-4-15)14-1-5-20(22,23)6-2-14/h9-10,14-15H,1-8,11H2,(H2,24,27)
    Synonyms
    1H-Isoindole-4-carboxamide, 2-(1-(4,4-difluorocyclohexyl)-4-piperidinyl)-6-fluoro-2,3-dihydro-3-oxo- | AT32155 | EX-A...
  7. (E/Z)-GSK-3β inhibitor 1
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    (E/Z)-GSK-3β inhibitor 1
    CAS: 3367-88-2 PubChem CID: 5796182 Formula: C14H10N2O Molecular Weight: 222.24
    ≥99%
    Out of Stock Item #: G650986
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    Technical Identifiers
    IUPAC Name
    (3Z)-3-(pyridin-2-ylmethylidene)-1H-indol-2-one
    SMILES
    C1=CC=C2C(=C1)C(=CC3=CC=CC=N3)C(=O)N2
    InChIKey
    YKQONSWBHGBDSB-XFXZXTDPSA-N
    InChI
    1S/C14H10N2O/c17-14-12(9-10-5-3-4-8-15-10)11-6-1-2-7-13(11)16-14/h1-9H,(H,16,17)/b12-9-
    Synonyms
    SR-01000594625 | GSK-3 | PIPAZETATE HYDROCHLORIDE [MART.] | EX-A7535 | BDBM50523811 | GSK-3beta inhibitor 1 | MS-2324...
  9. GSK-3β inhibitor 1
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    GSK-3β inhibitor 1
    CAS: 187325-53-7 PubChem CID: 5796182 Formula: C14H10N2O Molecular Weight: 222.24
    ≥98%
    Out of Stock Item #: G651681
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (3Z)-3-(pyridin-2-ylmethylidene)-1H-indol-2-one
    SMILES
    C1=CC=C2C(=C1)C(=CC3=CC=CC=N3)C(=O)N2
    InChIKey
    YKQONSWBHGBDSB-XFXZXTDPSA-N
    InChI
    1S/C14H10N2O/c17-14-12(9-10-5-3-4-8-15-10)11-6-1-2-7-13(11)16-14/h1-9H,(H,16,17)/b12-9-
    Synonyms
    SR-01000594625 | GSK-3 | PIPAZETATE HYDROCHLORIDE [MART.] | EX-A7535 | BDBM50523811 | GSK-3beta inhibitor 1 | MS-2324...
  10. N-Desethyl Sunitinib
    Wish List Compare
    N-Desethyl Sunitinib
    CAS: 356068-97-8 Formula: C20H23FN4O2 Molecular Weight: 370.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: N1494195
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    Technical Identifiers
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