Tyrosine-protein kinase txk (TXK)
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19 products
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- BMS-986142CAS: 1643368-58-4 Formula: C32H30F2N4O4 Molecular Weight: 572.60Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%Out of Stock Item #: B413993View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (7S)-3-fluoro-4-[3-(8-fluoro-1-methyl-2,4-dioxoquinazolin-3-yl)-2-methylphenyl]-7-(2-hydroxypropan-2-yl)-6,7,8,9-tetrahydro-5H-carbazole-1-carboxamide
- SMILES
- CC1=C(C=CC=C1N2C(=O)C3=C(C(=CC=C3)F)N(C2=O)C)C4=C(C=C(C5=C4C6=C(N5)CC(CC6)C(C)(C)O)C(=O)N)F
- InChIKey
- ZRYMMWAJAFUANM-INIZCTEOSA-N
- InChI
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- Synonyms
- (2S)-6-fluoro-5-[3-(8-fluoro-1-methyl-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-2-methylphenyl]-2-(2-hydroxypropan-2-...
- Branebrutinib (BMS-986195), Inhibitor of Bruton tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%Out of Stock Item #: B414208View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[(3S)-3-(but-2-ynoylamino)piperidin-1-yl]-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide
- SMILES
- CC#CC(=O)NC1CCCN(C1)C2=C(C=C(C3=C2C(=C(N3)C)C)C(=O)N)F
- InChIKey
- VJPPLCNBDLZIFG-ZDUSSCGKSA-N
- InChI
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- Synonyms
- 4-((3S)-3-(2-Butynoylamino)-1-piperidinyl)-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide | 4-((3S)-3-(2-BUTYNOYLAMINO...
- Ritlecitinib (PF-06651600), TEC family kinase inhibitorCAS: 1792180-81-4 EC Number: 815-269-7 PubChem CID: 118115473 Formula: C15H19N5O Molecular Weight: 285.34Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSOIn Stock Item #: R422181View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
- SMILES
- C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O
- InChIKey
- CBRJPFGIXUFMTM-WDEREUQCSA-N
- InChI
- 1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
- Synonyms
- DB14924 | Ritlecitinib? | RITLECITINIB [WHO-DD] | PF06651600;PF 06651600 | GTPL9559 | DS-13951 | HY-100754 | AC-35550...
- Ritlecitinib (PF-06651600), TEC family kinase inhibitorCAS: 1792180-81-4 EC Number: 815-269-7 PubChem CID: 118115473 Formula: C15H19N5O Molecular Weight: 285.34Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%In Stock Item #: R414045View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
- SMILES
- C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O
- InChIKey
- CBRJPFGIXUFMTM-WDEREUQCSA-N
- InChI
- 1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
- Synonyms
- DB14924 | RITLECITINIB [WHO-DD] | PF06651600;PF 06651600 | GTPL9559 | DS-13951 | HY-100754 | AC-35550 | PF 06651600 |...
- 2-methyl-N-(2-{[3-(prop-2-enamido)phenyl]amino}pyrimidin-5-yl)-5-[3-(trifluoromethyl)benzamido]benzamide, Inhibitor of BLK proto-oncogene; Src family tyrosine kinase;Inhibitor of BMX non-receptor tyrosine kinase;Inhibitor of Bruton tyrosine kinase;Inhibitor of tec protein tyrosine kinase;Inhibitor of TXK tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.Out of Stock Item #: M609107View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-methyl-N-(2-{[3-(prop-2-enamido)phenyl]amino}pyrimidin-5-yl)-5-[3-(trifluoromethyl)benzamido]benzamide
- SMILES
- C=CC(=O)Nc1cccc(c1)Nc1ncc(cn1)NC(=O)c1cc(ccc1C)NC(=O)c1cccc(c1)C(F)(F)F
- InChIKey
- BTWVWABAWDKQNJ-UHFFFAOYSA-N
- InChI
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- Synonyms
- Q27076563 | BDBM50020471 | SCHEMBL15998146 | 2-methyl-N-(2-{[3-(prop-2-enamido)phenyl]amino}pyrimidin-5-yl)-5-[3-(tri...
- 2-methyl-N-[2-({3-[2-(prop-2-enamido)acetamido]phenyl}amino)pyrimidin-5-yl]-5-[3-(trifluoromethyl)benzamido]benzamide, Inhibitor of BLK proto-oncogene; Src family tyrosine kinase;Inhibitor of BMX non-receptor tyrosine kinase;Inhibitor of Bruton tyrosine kinase;Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2;Inhibitor of erb-b2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.Out of Stock Item #: M609151View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-methyl-N-[2-({3-[2-(prop-2-enamido)acetamido]phenyl}amino)pyrimidin-5-yl]-5-[3-(trifluoromethyl)benzamido]benzamide
- SMILES
- C=CC(=O)NCC(=O)Nc1cccc(c1)Nc1ncc(cn1)NC(=O)c1cc(ccc1C)NC(=O)c1cccc(c1)C(F)(F)F
- InChIKey
- SMOPKEHQPPXRSH-UHFFFAOYSA-N
- InChI
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- Synonyms
- compound 38
- atuzabrutinib, Inhibitor of Bruton tyrosine kinaseCAS: 1581714-49-9 EC Number: 852-695-2 PubChem CID: 73438222 Formula: C30H30FN7O2 Molecular Weight: 539.60Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%In Stock Item #: A607809View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4,4-dimethylpent-2-enenitrile
- SMILES
- Nc1c2c(ncn1)n(nc2c1c(cc(cc1)Oc1ccccc1)F)[C@H]1CN(CCC1)C(=O)/C(=C/C(C)(C)C)/C#N
- InChIKey
- KZMQPYCXSAGLTB-ZWUNQBBJSA-N
- InChI
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- Synonyms
- PRN473 | SAR444727
- tirabrutinib, Tyrosine-protein kinase BTK inhibitorCAS: 1351636-18-4 EC Number: 888-020-3 PubChem CID: 54755438 Formula: C25H22N6O3 Molecular Weight: 454.5Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.Out of Stock Item #: T614478View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one
- SMILES
- CC#CC(=O)N1CCC(C1)N2C3=NC=NC(=C3N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5)N
- InChIKey
- SEJLPXCPMNSRAM-GOSISDBHSA-N
- InChI
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- Synonyms
- DB15227 | Q27283239 | 6-Amino-9-((3R)-1-(2-butynoyl)-3-pyrrolidinyl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one |...
- 3-[[4-(5-hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzenesulfonamide, Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of spleen associated tyrosine kinase;Inhibitor of TXK tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.Out of Stock Item #: H608970View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[[4-(5-hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzenesulfonamide
- SMILES
- Oc1ccc(c(c1)Nc1ccnc(n1)Nc1cccc(c1)S(=O)(=O)N)C
- InChIKey
- LKLIRPMEYRVLFV-UHFFFAOYSA-N
- InChI
- 1S/C17H17N5O3S/c1-11-5-6-13(23)10-15(11)21-16-7-8-19-17(22-16)20-12-3-2-4-14(9-12)26(18,24)25/h2-10,23H,1H3,(H2,18,24,25)(H2,19,20,21,22)
- Synonyms
- compound 23
- 3-[(2Z)-2-[5-(difluoromethyl)-1,2-dihydrothieno[3,2-c]pyrazol-3-ylidene]indol-6-yl]pentan-3-ol, Inhibitor of IL2 inducible T cell kinase;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of spleen associated tyrosine kinase;Inhibitor of TXK tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.Out of Stock Item #: Z609425View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(2Z)-2-[5-(difluoromethyl)-1,2-dihydrothieno[3,2-c]pyrazol-3-ylidene]indol-6-yl]pentan-3-ol
- SMILES
- CCC(c1ccc2c(c1)[nH]c(c2)c1n[nH]c2c1sc(c2)C(F)F)(CC)O
- InChIKey
- CQZZZUNOWZUNNG-UHFFFAOYSA-N
- InChI
- 1S/C19H19F2N3OS/c1-3-19(25,4-2)11-6-5-10-7-13(22-12(10)8-11)16-17-14(23-24-16)9-15(26-17)18(20)21/h5-9,18,22,25H,3-4H2,1-2H3,(H,23,24)
- Synonyms
- thienopyrazolylindole inhibitor 477 | compound 7
- Rilzabrutinib(PRN1008), Tyrosine-protein kinase BTK inhibitorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%In Stock Item #: R613193View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC(C)(\C=C(/C#N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12)N1CCN(CC1)C1COC1
- InChIKey
- LCFFREMLXLZNHE-GBOLQPHISA-N
- InChI
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- Synonyms
- BDBM143212 | PRN 1008 | UNII-5G1WE425BI | Q50825085 | UNII-NWN58M4F5T | WHO 10966 | (R,E)-2-(3-(4-amino-3-(2-fluoro-4...
- JAK3-IN-1Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSOOut of Stock Item #: J654830View ProductPricing & Pack Sizes
Technical Identifiers
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