PERK
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55 produkte
Beliebte Produkte
- GSK PERK inhibitor, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3;Inhibitor of myosin light chain kinase 2CAS: 1337531-89-1 Summenformel: C24H19F4N5O Molekulargewicht: 469.43Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Auf Lager — US-Lager, Versand in die EU* Artikel #: G355474Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone
- SMILES
- CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC(=C5)F)C(F)(F)F
- InChIKey
- PXVQGBJMIQCDEX-UHFFFAOYSA-N
- InChI
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- Synonyme
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2, 3-dihydroindol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]eth...
- GSK2606414CAS: 1337531-36-8 Summenformel: C24H20F3N5O Molekulargewicht: 451.44Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Auf Lager — US-Lager, Versand in die EU* Artikel #: G125654Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
- SMILES
- CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
- InChIKey
- SIXVRXARNAVBTC-UHFFFAOYSA-N
- InChI
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- Synonyme
- AC-29016 | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone...
- GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3CAS: 1337532-29-2 Summenformel: C23H21FN6O Molekulargewicht: 416.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Auf Lager — US-Lager, Versand in die EU* Artikel #: G276179Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
- SMILES
- CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
- InChIKey
- PRWSIEBRGXYXAJ-UHFFFAOYSA-N
- InChI
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- Synonyme
- 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
- ONO 8130, Antagonist of EP 1 receptorCAS: 459841-96-4 Summenformel: C25H28N2O5S2 Molekulargewicht: 500.63Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)◐ .Auf Bestellung · 8–12 Wochen Artikel #: O287851Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- 4-[[6-[2-methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]oxymethyl]benzoic acid
- SMILES
- CC1=CSC(=N1)S(=O)(=O)N(CC(C)C)C2=C(C=C3CCCC3=C2)OCC4=CC=C(C=C4)C(=O)O
- InChIKey
- IOXMDBQCUCDLAF-UHFFFAOYSA-N
- InChI
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- Synonyme
- AC-36636 | BDBM190564 | 4-[[6-[2-methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]o...
- VU 0424465, Agonist of mGlu 5 receptor;Allosteric modulator of mGlu 5 receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)◐ .Auf Bestellung · 8–12 Wochen Artikel #: V286883Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- 5-[2-(3-fluorophenyl)ethynyl]-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]pyridine-2-carboxamide
- SMILES
- CC(C(C)(C)O)NC(=O)C1=NC=C(C=C1)C#CC2=CC(=CC=C2)F
- InChIKey
- ZPKZAFDYFVJULO-CYBMUJFWSA-N
- InChI
- 1S/C19H19FN2O2/c1-13(19(2,3)24)22-18(23)17-10-9-15(12-21-17)8-7-14-5-4-6-16(20)11-14/h4-6,9-13,24H,1-3H3,(H,22,23)/t13-/m1/s1
- Synonyme
- 5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
- AMG PERK 44CAS: 1883548-84-2 Summenformel: C34H28N4O2•HCl Molekulargewicht: 561.07● Auf Lager — US-Lager, Versand in die EU* Artikel #: A286749Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one;hydrochloride
- SMILES
- CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(C=C6)C.Cl
- InChIKey
- RNAKBTDDCHJCMT-UHFFFAOYSA-N
- InChI
- show more
- Synonyme
- 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
- NSC 295642CAS: 77111-29-6 Summenformel: C15H14ClCuN3S2 Molekulargewicht: 399.42◐ .Auf Bestellung · 8–12 Wochen Artikel #: N352361Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane;chlorocopper(1+)
- SMILES
- CC(=NN=C([S-])SCC1=CC=CC=C1)C2=CC=CC=N2.Cl[Cu+]
- InChIKey
- MGXCRQNCPJBYKM-CWQUOYFRSA-L
- InChI
- 1S/C15H15N3S2.ClH.Cu/c1-12(14-9-5-6-10-16-14)17-18-15(19)20-11-13-7-3-2-4-8-13;;/h2-10H,11H2,1H3,(H,18,19);1H;/q;;+2/p-2/b17-12+;;
- Synonyme
- (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane;chlorocopper(1+) | DTXSID20444568 | N...
- ISRIB (trans-isomer)CAS: 1597403-47-8 Summenformel: C22H24Cl2N2O4 Molekulargewicht: 451.34● Auf Lager — US-Lager, Versand in die EU* Artikel #: I275318Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- 2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide
- SMILES
- C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl
- InChIKey
- HJGMCDHQPXTGAV-UHFFFAOYSA-N
- InChI
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- Synonyme
- ISRIB | ISRIB trans-isomer | BCP23947 | ISRIB, >=98% (HPLC) | N,N'-(Cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)aceta...
- S-(Carboxymethyl)-L-cysteine● Auf Lager — US-Lager, Versand in die EU* Artikel #: S161422Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid
- SMILES
- N[C@@H](CSCC(O)=O)C(O)=O
- InChIKey
- GBFLZEXEOZUWRN-VKHMYHEASA-N
- InChI
- 1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
- Synonyme
- Carbocysteine, L Isomer | Chilvax | Mucodyne | (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid | (2R)-2-amino-3-...
- WKYMVmCAS: 187986-17-0 Summenformel: C41H61N9O7S2 Molekulargewicht: 856.11● Auf Lager — US-Lager, Versand in die EU* Artikel #: W275202Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- Synonyme
- Leukocyte chemoattractant peptide
- Obestatin human(trifluoroacetate salt)CAS: 1081110-72-6 PubChem CID: 146156385 Summenformel: C116H176N32O33（free basis） Molekulargewicht: 2546.86（free basis）● Auf Lager — US-Lager, Versand in die EU* Artikel #: O287703Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
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- SMILES
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- InChIKey
- IXQOGPZNKNSCJR-UHFFFAOYSA-N
- InChI
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- GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3CAS: 1337532-29-2 Summenformel: C23H21FN6O Molekulargewicht: 416.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● Auf Lager — US-Lager, Versand in die EU* Artikel #: G421276Produkt anzeigenPreise & Packungsgrößen
Technische Identifikatoren
- IUPAC-Bezeichnung
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
- SMILES
- CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
- InChIKey
- PRWSIEBRGXYXAJ-UHFFFAOYSA-N
- InChI
- show more
- Synonyme
- 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
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Häufig gestellte Fragen
How is the PERK listing put together?
It draws on reported PERK annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a PERK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the PERK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for PERK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For PERK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the PERK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of PERK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.