Integrin

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  1. GR 144053 Trihydrochlorid
    CAS: 1215333-48-4 PubChem CID: 16759148 Summenformel: C18H30Cl3N5O2 Molekulargewicht: 454.83
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: G288867
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    2-[4-[4-(4-carbamimidoylphenyl)piperazin-1-yl]piperidin-1-yl]acetic acid;trihydrochloride
    SMILES
    C1CN(CCC1N2CCN(CC2)C3=CC=C(C=C3)C(=N)N)CC(=O)O.Cl.Cl.Cl
    InChIKey
    YKRNPHOBDOUQTG-UHFFFAOYSA-N
    InChI
    1S/C18H27N5O2.3ClH/c19-18(20)14-1-3-15(4-2-14)22-9-11-23(12-10-22)16-5-7-21(8-6-16)13-17(24)25;;;/h1-4,16H,5-13H2,(H3,19,20)(H,24,25);3*1H
    Synonyme
    4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidinessigsäuretrihydrochlorid | 2-(4-(4-(4-Carbamimidoylpheny...
  2. Lifitegrast, Integrin alpha-L/beta-2 (LFA-1) antagonist
    CAS: 1025967-78-5 EG-Nummer: 813-044-8 Summenformel: C29H24Cl2N2O7S Molekulargewicht: 615.48
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: L171714
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    (2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid
    SMILES
    CS(=O)(=O)C1=CC=CC(=C1)CC(C(=O)O)NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl
    InChIKey
    JFOZKMSJYSPYLN-QHCPKHFHSA-N
    InChI
    1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2show more
    Synonyme
    EN300-20605731 | 7-hydroxy-2-methyl-3-phenoxy-chromone | s3714 | A900838 | Q23044263 | N-(2-(1-benzofuran-6-carbonyl)...
  3. Leukadherin-1
    CAS: 344897-95-6 Summenformel: C22H15NO4S2 Molekulargewicht: 421.49
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: L275488
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    4-[5-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)CN2C(=O)C(=CC3=CC=C(O3)C4=CC=C(C=C4)C(=O)O)SC2=S
    InChIKey
    AEZGRQSLKVNPCI-UNOMPAQXSA-N
    InChI
    1S/C22H15NO4S2/c24-20-19(29-22(28)23(20)13-14-4-2-1-3-5-14)12-17-10-11-18(27-17)15-6-8-16(9-7-15)21(25)26/h1-12H,13H2,(H,25,26)/b19-12-
    Synonyme
    Leukadherin 1 | SCHEMBL18301010 | HY-15701 | (Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-y...
  4. Gly-Arg-Gly-Asp-Ser TFA
    CAS: 96426-21-0(free base) Summenformel: C17H30N8O9·xC2HF3O2 Molekulargewicht: 490.47(free base)
    Feststoff ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: G305036
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    L-Serine, N-(N-(N-(N2-glycyl-L-arginyl)glycyl)-L-alpha-aspartyl)- | Gly-Arg-Gly-Asp-Ser, >=97% (HPLC) | NH2-Gly-Arg-G...
  5. BIO 5192
    CAS: 327613-57-0 Summenformel: C38H46Cl2N6O8S Molekulargewicht: 817.78
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: B286648
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    (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl-[2-[4-[(2-methylphenyl)carbamoylamino]phenyl]aceshow more
    SMILES
    CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N(C)C(CC(C)C)C(=O)NCCC(C(=O)O)NC(=O)C3CCCN3S(=O)(=O)C4=CC(=CC(=C4)Cl)Cl
    InChIKey
    MNQBPRHHZPXCKZ-ZDCRTTOTSA-N
    InChI
    1S/C38H46Cl2N6O8S/c1-23(2)18-33(45(4)34(47)19-25-11-13-28(14-12-25)42-38(52)44-30-9-6-5-8-24(30)3)35(48)41-16-15-31(37(50)51)43-36(49)32-10-7-17-46(32show more
    Synonyme
    (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2...
  6. BIRT 377, Inhibitor of integrin; alpha L subunit (antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide)
    CAS: 213211-10-0 Summenformel: C18H15BrCl2N2O2 Molekulargewicht: 442.13
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: B287562
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    (5R)-5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione
    SMILES
    CC1(C(=O)N(C(=O)N1C)C2=CC(=CC(=C2)Cl)Cl)CC3=CC=C(C=C3)Br
    InChIKey
    FJNJHZQMQRVZEE-GOSISDBHSA-N
    InChI
    1S/C18H15BrCl2N2O2/c1-18(10-11-3-5-12(19)6-4-11)16(24)23(17(25)22(18)2)15-8-13(20)7-14(21)9-15/h3-9H,10H2,1-2H3/t18-/m1/s1
    Synonyme
    (5R)-5-[(4-Bromphenyl)methyl]-3-(3,5-dichlorphenyl)-1,5-dimethyl-2,4-imidazolidindion
  7. A 286982, Inhibitor of integrin αLβ2
    CAS: 280749-17-9 Summenformel: C24H27N3O4S Molekulargewicht: 453.55
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: A288284
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    (E)-1-(4-acetylpiperazin-1-yl)-3-[3-nitro-4-(2-propan-2-ylphenyl)sulfanylphenyl]prop-2-en-1-one
    SMILES
    CC(C)C1=CC=CC=C1SC2=C(C=C(C=C2)C=CC(=O)N3CCN(CC3)C(=O)C)[N+](=O)[O-]
    InChIKey
    HTGGAYLWTDOFDK-PKNBQFBNSA-N
    InChI
    1S/C24H27N3O4S/c1-17(2)20-6-4-5-7-22(20)32-23-10-8-19(16-21(23)27(30)31)9-11-24(29)26-14-12-25(13-15-26)18(3)28/h4-11,16-17H,12-15H2,1-3H3/b11-9+
    Synonyme
    A286982 | A899560 | UNII-5I8WFS075A | BDBM50092956 | F77491 | A 286,982 | (2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1...
  8. Arg-Gly-Asp-Ser
    CAS: 91037-65-9 Summenformel: C15H27N7O8 Molekulargewicht: 433.42
    Feststoff ≥95%(HPLC)
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: A101721
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    (3S)-3-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-4-oxobutanoic acid
    SMILES
    C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)N)CN=C(N)N
    InChIKey
    NNRFRJQMBSBXGO-CIUDSAMLSA-N
    InChI
    1S/C15H27N7O8/c16-7(2-1-3-19-15(17)18)12(27)20-5-10(24)21-8(4-11(25)26)13(28)22-9(6-23)14(29)30/h7-9,23H,1-6,16H2,(H,20,27)(H,21,24)(H,22,28)(H,25,26)show more
    Synonyme
    RGDS | (S)-3-[2-((S)-2-Amino-5-guanidino-pentanoylamino)-acetylamino]-N-((R)-1-carboxy-2-hydroxy-ethyl)-succinamic ac...
  9. Eptifibatide acetate
    CAS: 881997-86-0 PubChem CID: 12001375 Summenformel: C35H49N11O9S2·xC2H4O2 Molekulargewicht: 831.96 (free base basis)
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: E339599
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    acetic acid;2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,show more
    SMILES
    CC(=O)O.C1CC2C(=O)NC(CSSCCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N
    InChIKey
    KWKBRYJYRIUYEI-QMYFOHRPSA-N
    InChI
    1S/C35H49N11O9S2.C2H4O2/c36-30(51)25-18-57-56-13-10-27(47)42-22(8-3-4-11-39-35(37)38)31(52)41-17-28(48)43-23(15-29(49)50)32(53)44-24(14-19-16-40-21-7-show more
    Synonyme
    acetic acid;2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,1...
  10. Surfactin(mixture of isomers)
    CAS: 252023-70-4 EG-Nummer: 607-428-2 Summenformel: Molekulargewicht: 1025.04(Average)
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95% mixture of isomers
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: S329585
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    3-[(3S,6R,9S,12S,15R,18S,21S,25R)-9-(carboxymethyl)-3,6,15,18-tetrakis(2-methylpropyl)-25-(10-methylundecyl)-2,5,8,11,14,17,20,23-octaoxo-12-propan-2-show more
    SMILES
    CC(C)CCCCCCCCCC1CC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)O1)CC(C)C)CC(C)C)CC(=O)O)C(C)C)CC(C)C)CC(C)C)CCC(=O)O
    InChIKey
    NJGWOFRZMQRKHT-WGVNQGGSSA-N
    InChI
    1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52show more
    Synonyme
    surfactin C | 3-[(3S,6R,9S,12S,15R,18S,21S,25R)-9-(carboxymethyl)-3,6,15,18-tetrakis(2-methylpropyl)-25-(10-methylund...
  11. Zaurategrast, Inhibitor of integrin α4β1;Inhibitor of integrin α4β7;Inhibitor of integrin; alpha 4 subunit (antigen CD49D; alpha 4 subunit of VLA-4 receptor)
    CAS: 455264-31-0 EG-Nummer: 630-608-7 PubChem CID: 10186367 Summenformel: C26H25BrN4O3 Molekulargewicht: 521.42
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: Z126002
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    (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2,7-naphthyridin-1-ylamino)phenyl]propanoic acid
    SMILES
    C1CCC2(CC1)C(=C(C2=O)Br)NC(CC3=CC=C(C=C3)NC4=NC=CC5=C4C=NC=C5)C(=O)O
    InChIKey
    KYHVWHYLKOHLKA-FQEVSTJZSA-N
    InChI
    1S/C26H25BrN4O3/c27-21-22(26(23(21)32)10-2-1-3-11-26)31-20(25(33)34)14-16-4-6-18(7-5-16)30-24-19-15-28-12-8-17(19)9-13-29-24/h4-9,12-13,15,20,31H,1-3,show more
    Synonyme
    HY-70073 | AKOS016005046 | NCGC00378753-01 | DTXSID90196547 | Zaurategrast | CT7758 | CT-7758 | ZAURATEGRAST [WHO-DD]...
  12. A-205804
    CAS: 251992-66-2 Summenformel: C15H12N2OS2 Molekulargewicht: 300.39
    Feststoff ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: A129416
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    4-(4-methylphenyl)sulfanylthieno[2,3-c]pyridine-2-carboxamide
    SMILES
    CC1=CC=C(C=C1)SC2=C3C=C(SC3=CN=C2)C(=O)N
    InChIKey
    QQGWEXFLMJGCAL-UHFFFAOYSA-N
    InChI
    1S/C15H12N2OS2/c1-9-2-4-10(5-3-9)19-13-7-17-8-14-11(13)6-12(20-14)15(16)18/h2-8H,1H3,(H2,16,18)
    Synonyme
    1-Des-arg-bradykinin | NCGC00167761-01 | J-015866 | MFCD09038566 | Q27195214 | 4-(p-tolylthio)thieno[2,3-c]pyridine-2...
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Häufig gestellte Fragen

How is the Integrin listing put together?
It draws on reported Integrin annotations within Cytoskeleton and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Integrin modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Integrin entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Integrin compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Integrin work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Integrin compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Integrin compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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