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MARCKS

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  1. TPPB
    Wunschliste Zur Vergleichsliste hinzufügen
    TPPB
    CAS: 497259-23-1 PubChem CID: 9935767 Summenformel: C27H30F3N3O3 Molekulargewicht: 501.54
    ≥99%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: T303812
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    IUPAC-Bezeichnung
    (2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dishow more
    SMILES
    CC(C)C1C(=O)NC(CC2=C(N1C)C=CC(=C2)NC(=O)C=CC=CC3=CC=C(C=C3)C(F)(F)F)CO
    InChIKey
    WOLVEMPZUIFSII-IHHOKICGSA-N
    InChI
    1S/C27H30F3N3O3/c1-17(2)25-26(36)32-22(16-34)15-19-14-21(12-13-23(19)33(25)3)31-24(35)7-5-4-6-18-8-10-20(11-9-18)27(28,29)30/h4-14,17,22,25,34H,15-16Hshow more
    Synonyme
    AS-82981 | WOLVEMPZUIFSII-IHHOKICGSA-N | PKC Activator V | 5-(4-Trifluoromethyl-phenyl)-penta-2,4-dienoic acid (5-hyd...
  2. Sotrastaurin - Moligand™, ≥98% CAS No(425637-18-9) by Aladdin Scientific
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    Sotrastaurin, Protein kinase C (PKC) inhibitor
    CAS: 425637-18-9 PubChem CID: 10296883 Summenformel: C25H22N6O2 Molekulargewicht: 438.49
    Feststoff Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Auf Lager — US-Lager, Versand in die EU* Artikel #: S125985
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    IUPAC-Bezeichnung
    3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione
    SMILES
    CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65
    InChIKey
    OAVGBZOFDPFGPJ-UHFFFAOYSA-N
    InChI
    1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,show more
    Synonyme
    AKOS027422723 | 3-(1H-Indol-3-yl)-4-(2-(4-methylpiperazin-1-yl)quinazolin-4-yl)-1H-pyrrole-2,5-dione | EX-A2802 | 105...
  3. balanol, Inhibitor of beta adrenergic receptor kinase 1;Inhibitor of beta adrenergic receptor kinase 2;Inhibitor of G protein-coupled receptor kinase 1;Inhibitor of G protein-coupled receptor kinase 4;Inhibitor of G protein-coupled receptor kinase 6;Inhibitor of G
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    balanol, Inhibitor of beta adrenergic receptor kinase 1;Inhibitor of beta adrenergic receptor kinase 2;Inhibitor of G protein-coupled receptor kinase 1;Inhibitor of G protein-coupled receptor kinase 4;Inhibitor of G protein-coupled receptor kinase 6;Inhibitor of G
    CAS: 63590-19-2 PubChem CID: 5287736 Summenformel: C28H26N2O10 Molekulargewicht: 550.51
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: B607920
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    IUPAC-Bezeichnung
    2-[2,6-dihydroxy-4-[(3R,4R)-3-[(4-hydroxybenzoyl)amino]azepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
    SMILES
    C1CC(C(CNC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O
    InChIKey
    XYUFCXJZFZPEJD-XMSQKQJNSA-N
    InChI
    1S/C28H26N2O10/c31-16-8-6-14(7-9-16)26(36)30-18-13-29-10-2-5-22(18)40-28(39)15-11-20(33)24(21(34)12-15)25(35)23-17(27(37)38)3-1-4-19(23)32/h1,3-4,6-9,show more
    Synonyme
    Azepinostatin | Balanol, 1 | Q4850048 | BDBM3149 | BENZOIC ACID, 4-(2-CARBOXY-6-HYDROXYBENZOYL)-3,5-DIHYDROXY-, 1-(HE...
  11. VU0364572 TFA
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    VU0364572 TFA
    CAS: 1240514-89-9 PubChem CID: 91885398
    ≥99%
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: V1428420
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    IUPAC-Bezeichnung
    ethyl 4-[(3R)-3-[(2-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate;2,2,2-trifluoroacetic acid
    SMILES
    CCOC(=O)N1CCC(CC1)N2CCCC(C2)NC(=O)C3=CC=CC=C3C.C(=O)(C(F)(F)F)O
    InChIKey
    QEFQJTFXOBPBLZ-UNTBIKODSA-N
    InChI
    1S/C21H31N3O3.C2HF3O2/c1-3-27-21(26)23-13-10-18(11-14-23)24-12-6-8-17(15-24)22-20(25)19-9-5-4-7-16(19)2;3-2(4,5)1(6)7/h4-5,7,9,17-18H,3,6,8,10-15H2,1-show more
  12. BIO-11006 acetate
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    BIO-11006 acetate
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in Water
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: B1493853
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Häufig gestellte Fragen

How is the MARCKS listing put together?
It draws on reported MARCKS annotations within Cytoskeleton and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MARCKS modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MARCKS entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MARCKS compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MARCKS work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MARCKS compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MARCKS compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.
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