Guanylate Cyclase

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  1. YC-1, Activator of Guanylyl cyclase; α 1β 1;Activator of Guanylyl cyclase; α 2β 1
    CAS: 170632-47-0 PubChem CID: 5712 Formula: C19H16N2O2 Molecular Weight: 304.34
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: Y274733
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    IUPAC Name
    [5-(1-benzylindazol-3-yl)furan-2-yl]methanol
    SMILES
    C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)C4=CC=C(O4)CO
    InChIKey
    OQQVFCKUDYMWGV-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2
    Synonyms
    3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole | A907557 | YC1 | yc-1 | [5-[1-(phenylmethyl)indazol-3-yl]furan-2-yl]...
  2. Methylene blue
    CAS: 61-73-4 EC Number: 200-515-2 Formula: C16H18ClN3S Molecular Weight: 319.85
    Solid ≥70%
    In Stock Item #: M134389
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    IUPAC Name
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride
    SMILES
    CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]
    InChIKey
    CXKWCBBOMKCUKX-UHFFFAOYSA-M
    InChI
    1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1
    Synonyms
    Methylene Blue BB (Zinc Free) | Methylene Blue USP (Medicinal) | 3H-Phenothiazine, 7-(dimethylamino)-3-(methylimino)-...
  3. Methylene Blue hydrate
    CAS: 122965-43-9 Formula: C16H18ClN3S·xH2O Molecular Weight: 319.85 (anhydrous basis)
    In Stock Item #: M190219
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    IUPAC Name
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;hydrate
    SMILES
    CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.[Cl-]
    InChIKey
    WQVSELLRAGBDLX-UHFFFAOYSA-M
    InChI
    1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1
    Synonyms
    UNII-O3YJW1TB3C | O3YJW1TB3C | (+/-)-5-bromo-2-aminoindane hydrobromide | E79163 | FT-0775246 | Zinc free Methylene B...
  4. Methylene blue
    CAS: 7220-79-3 EC Number: 615-731-6 Formula: C16H18ClN3S·3H2O Molecular Weight: 373.9
    Indicator ? Indicator grade — characterized dye giving a defined color change at a known transition. Use to signal pH or titration endpoints visually.
    In Stock Item #: M102719
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    Technical Identifiers
    IUPAC Name
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
    SMILES
    CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]
    InChIKey
    XQAXGZLFSSPBMK-UHFFFAOYSA-M
    InChI
    1S/C16H18N3S.ClH.3H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;;;/h5-10H,1-4H3;1H;3*1H2/q+1;;;;/p-1
    Synonyms
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate | METHYLENE BLUE [IARC] | Methylene blu...
  5. Methylene Blue trihydrate
    CAS: 7220-79-3 EC Number: 615-731-6 Formula: C16H18ClN3S·3H2O Molecular Weight: 373.9
    Biological Stain ? Biological stain grade — dyes characterized for staining cells and tissues. Use in histology and microscopy where staining consistency matters. Purifed ? Purified grade — refined to remove major impurities for cleaner results. Use when crude material would introduce unwanted interference. ≥90%(HPLC)
    In Stock Item #: M102717
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    Technical Identifiers
    IUPAC Name
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
    SMILES
    CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]
    InChIKey
    XQAXGZLFSSPBMK-UHFFFAOYSA-M
    InChI
    1S/C16H18N3S.ClH.3H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;;;/h5-10H,1-4H3;1H;3*1H2/q+1;;;;/p-1
    Synonyms
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate | METHYLENE BLUE [IARC] | Methylene blu...
  6. BAY 41-2272, Activator of Guanylyl cyclase; α 1β 1
    CAS: 256376-24-6 Formula: C20H17FN6 Molecular Weight: 360.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: B303240
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    IUPAC Name
    5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine
    SMILES
    C1CC1C2=CN=C(N=C2N)C3=NN(C4=C3C=CC=N4)CC5=CC=CC=C5F
    InChIKey
    ATOAHNRJAXSBOR-UHFFFAOYSA-N
    InChI
    1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25)
    Synonyms
    CCG-268161 | 5-cyclopropyl-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine | 5-Cyclopropyl-2-[...
  7. BAY 41-8543
    CAS: 256498-66-5 Formula: C21H21FN8O Molecular Weight: 420.44
    Out of Stock Item #: B288616
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    Technical Identifiers
    IUPAC Name
    2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]-5-morpholin-4-ylpyrimidine-4,6-diamine
    SMILES
    C1COCCN1C2=C(N=C(N=C2N)C3=NN(C4=C3C=CC=N4)CC5=CC=CC=C5F)N
    InChIKey
    AQYFUZRYBJBAGZ-UHFFFAOYSA-N
    InChI
    1S/C21H21FN8O/c22-15-6-2-1-4-13(15)12-30-21-14(5-3-7-25-21)16(28-30)20-26-18(23)17(19(24)27-20)29-8-10-31-11-9-29/h1-7H,8-12H2,(H4,23,24,26,27)
    Synonyms
    AS-35182 | Q27256130 | 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-morpholinopyrimidine-4,6-diamine | b]p...
  8. Ebselen Oxide
    CAS: 104473-83-8 Formula: C13H9NO2Se Molecular Weight: 290.18
    In Stock Item #: E344603
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    IUPAC Name
    1-oxo-2-phenyl-1λ4,2-benzoselenazol-3-one
    SMILES
    C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2=O
    InChIKey
    SBTLFLABILGUMK-UHFFFAOYSA-N
    InChI
    1S/C13H9NO2Se/c15-13-11-8-4-5-9-12(11)17(16)14(13)10-6-2-1-3-7-10/h1-9H
    Synonyms
    NSC639772 | NSC-639772 | 1-oxo-2-phenyl-1lambda4,2-benzoselenazol-3-one | Ebselen Oxide | 1,2-Benzisoselenazole-1,3-d...
  9. Riociguat, Soluble guanylate cyclase positive allosteric modulator
    CAS: 625115-55-1 EC Number: 641-755-1 PubChem CID: 11304743 Formula: C20H19FN8O2 Molecular Weight: 422.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: R127750
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    IUPAC Name
    methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]-N-methylcarbamate
    SMILES
    CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC
    InChIKey
    WXXSNCNJFUAIDG-UHFFFAOYSA-N
    InChI
    1S/C20H19FN8O2/c1-28(20(30)31-2)15-16(22)25-18(26-17(15)23)14-12-7-5-9-24-19(12)29(27-14)10-11-6-3-4-8-13(11)21/h3-9H,10H2,1-2H3,(H4,22,23,25,26)
    Synonyms
    AMY4218 | HMS3413M12 | Methyl 4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl(methyl)...
  10. 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one, Inhibitor of Guanylyl cyclase; α 1β 1;Inhibitor of Guanylyl cyclase; α 2β 1
    CAS: 41443-28-1 EC Number: 637-000-0 Formula: C9H5N3O2 Molecular Weight: 187.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: H133434
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    IUPAC Name
    [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one
    SMILES
    C1=CC=C2C(=C1)N=CC3=NOC(=O)N23
    InChIKey
    LZMHWZHOZLVYDL-UHFFFAOYSA-N
    InChI
    1S/C9H5N3O2/c13-9-12-7-4-2-1-3-6(7)10-5-8(12)11-14-9/h1-5H
    Synonyms
    [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | EU-0100953 | 3-METHYL(1,1'-BIPHENYL)-4-AMINE | S57V2NMV38 | O0400 | Tocris...
  11. Ataciguat, Soluble guanylate cyclase activator
    CAS: 254877-67-3 Formula: C21H19Cl2N3O6S3 Molecular Weight: 576.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A358567
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    IUPAC Name
    5-chloro-2-[(5-chlorothiophen-2-yl)sulfonylamino]-N-(4-morpholin-4-ylsulfonylphenyl)benzamide
    SMILES
    C1COCCN1S(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=C(C=CC(=C3)Cl)NS(=O)(=O)C4=CC=C(S4)Cl
    InChIKey
    PQHLRGARXNPFCF-UHFFFAOYSA-N
    InChI
    1S/C21H19Cl2N3O6S3/c22-14-1-6-18(25-34(28,29)20-8-7-19(23)33-20)17(13-14)21(27)24-15-2-4-16(5-3-15)35(30,31)26-9-11-32-12-10-26/h1-8,13,25H,9-12H2,(H,show more
    Synonyms
    Ataciguat | GTPL5141 | A911275 | HY-17500 | 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfo...
  12. 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one, Inhibitor of Guanylyl cyclase; α 1β 1;Inhibitor of Guanylyl cyclase; α 2β 1
    CAS: 41443-28-1 EC Number: 637-000-0 Formula: C9H5N3O2 Molecular Weight: 187.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: H423879
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    Technical Identifiers
    IUPAC Name
    [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one
    SMILES
    C1=CC=C2C(=C1)N=CC3=NOC(=O)N23
    InChIKey
    LZMHWZHOZLVYDL-UHFFFAOYSA-N
    InChI
    1S/C9H5N3O2/c13-9-12-7-4-2-1-3-6(7)10-5-8(12)11-14-9/h1-5H
    Synonyms
    [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | EU-0100953 | 3-METHYL(1,1'-BIPHENYL)-4-AMINE | S57V2NMV38 | O0400 | Tocris...
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