Kallikrein

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  1. PKSI-527
    CAS: 128837-71-8 PubChem CID: 3035562 Formula: C25H32ClN3O4 Molecular Weight: 474
    Out of Stock Item #: P275072
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    Technical Identifiers
    IUPAC Name
    2-[4-[[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]acetic acid;hydrochloride
    SMILES
    C1CC(CCC1CN)C(=O)NC(CC2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)CC(=O)O.Cl
    InChIKey
    NAXNMKUKSBHHMP-QCXPCDNBSA-N
    InChI
    1S/C25H31N3O4.ClH/c26-16-19-6-10-20(11-7-19)24(31)28-22(14-17-4-2-1-3-5-17)25(32)27-21-12-8-18(9-13-21)15-23(29)30;/h1-5,8-9,12-13,19-20,22H,6-7,10-11show more
    Synonyms
    DTXSID00926216 | Benzeneacetic acid, 4-((2-(((4-(aminomethyl)cyclohexyl)carbonyl)amino)-1-oxo-3-phenylpropyl)amino)-,...
  2. LSP-249
    CAS: 1801253-04-2 Formula: C24H22ClN5O Molecular Weight: 431.92
    In Stock Item #: L413428
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    IUPAC Name
    N-[(6-amino-2,4-dimethylpyridin-3-yl)methyl]-2-[(3-chloroquinolin-6-yl)methyl]pyridine-4-carboxamide
    SMILES
    CC1=CC(=NC(=C1CNC(=O)C2=CC(=NC=C2)CC3=CC4=CC(=CN=C4C=C3)Cl)C)N
    InChIKey
    BDLURRLRBKLEDL-UHFFFAOYSA-N
    InChI
    1S/C24H22ClN5O/c1-14-7-23(26)30-15(2)21(14)13-29-24(31)17-5-6-27-20(11-17)9-16-3-4-22-18(8-16)10-19(25)12-28-22/h3-8,10-12H,9,13H2,1-2H3,(H2,26,30)(H,show more
  3. avoralstat, Plasma kallikrein inhibitor
    CAS: 918407-35-9 EC Number: 811-719-1 PubChem CID: 86566678 Formula: C28H27N5O5 Molecular Weight: 513.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: A607821
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    IUPAC Name
    3-[2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl]-6-(cyclopropylmethylcarbamoyl)pyridine-2-carboxylic acid
    SMILES
    COC1=CC(=C(C=C1C=C)C(=O)NC2=CC=C(C=C2)C(=N)N)C3=C(N=C(C=C3)C(=O)NCC4CC4)C(=O)O
    InChIKey
    TUWMKPVJGGWGNL-UHFFFAOYSA-N
    InChI
    1S/C28H27N5O5/c1-3-16-12-21(26(34)32-18-8-6-17(7-9-18)25(29)30)20(13-23(16)38-2)19-10-11-22(33-24(19)28(36)37)27(35)31-14-15-4-5-15/h3,6-13,15H,1,4-5,show more
    Synonyms
    3-(2-((4-carbamimidoylphenyl)carbamoyl)-5-methoxy-4-vinylphenyl)-6-((cyclopropylmethyl)carbamoyl)picolinic acid | BCX...
  4. ecallantide, INHIBITOR of Plasma kallikrein inhibitor
    CAS: 460738-38-9 PubChem CID: 44152182
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: rp173941
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    Technical Identifiers
    SMILES
    CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4CCC[C@H]4C(=O)N[C@H](C(=O)N[C@Hshow more
    InChIKey
    VBGWSQKGUZHFPS-VGMMZINCSA-N
    Synonyms
    DX-88 | Kalbitor | GTPL6955 | FOV2302 | Ecallantide
  5. berotralstat, Inhibitor of kallikrein B1
    CAS: 1809010-50-1 PubChem CID: 137528262
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: B608004
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    IUPAC Name
    2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
    SMILES
    C1CC1CNC(C2=CC(=C(C=C2)F)NC(=O)C3=CC(=NN3C4=CC=CC(=C4)CN)C(F)(F)F)C5=CC=CC(=C5)C#N
    InChIKey
    UXNXMBYCBRBRFD-MUUNZHRXSA-N
    InChI
    1S/C30H26F4N6O/c31-24-10-9-22(28(37-17-18-7-8-18)21-5-1-3-19(11-21)15-35)13-25(24)38-29(41)26-14-27(30(32,33)34)39-40(26)23-6-2-4-20(12-23)16-36/h1-6,show more
    Synonyms
    EU-0100725 | EX-A5537 | HY-109127 | Tin, rod, 500mm, diameter 9.5mm, 99.75% | BDBM50602174 | Q413540 | Orladeyo | 1-[...
  6. PPACK II diTFA
    CAS: 649748-23-2 PubChem CID: 131698209 Formula: C29H35ClF6N6O7 Molecular Weight: 615.04
    Out of Stock Item #: P648671
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    IUPAC Name
    (2R)-2-amino-N-[(2S)-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide;2,2,2-trifluoshow more
    SMILES
    C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)CCl)N.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O
    InChIKey
    JVMDQRDDGVKUMG-WOSURGFKSA-N
    InChI
    1S/C25H33ClN6O3.2C2HF3O2/c26-16-22(33)20(12-7-13-30-25(28)29)31-24(35)21(15-18-10-5-2-6-11-18)32-23(34)19(27)14-17-8-3-1-4-9-17;2*3-2(4,5)1(6)7/h1-6,8show more
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