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CRAC Channel

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  1. YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
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    YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
    CAS: 223499-30-7 EC Number: 636-569-2 PubChem CID: 2455 Formula: C15H9F6N5OS Molecular Weight: 421.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: Y276423
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    Technical Identifiers
    IUPAC Name
    N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
    SMILES
    CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
    InChIKey
    XPRZIORDEVHURQ-UHFFFAOYSA-N
    InChI
    1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
    Synonyms
    HMS3648I22 | AS-16763 | CRAC Channel Inhibitor, BTP2 | SR-01000644222-3 | NCGC00344111-03 | AC-35791 | HMS3886H10 | I...
  2. MRS 1845
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    MRS 1845
    CAS: 544478-19-5 Formula: C21H22N2O6 Molecular Weight: 398.41
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: M336287
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    IUPAC Name
    5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1-prop-2-ynyl-4H-pyridine-3,5-dicarboxylate
    SMILES
    CCOC(=O)C1=C(N(C(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)CC#C)C
    InChIKey
    BITHABUTZRAUGT-UHFFFAOYSA-N
    InChI
    1S/C21H22N2O6/c1-6-11-22-13(3)17(20(24)28-5)19(18(14(22)4)21(25)29-7-2)15-9-8-10-16(12-15)23(26)27/h1,8-10,12,19H,7,11H2,2-5H3
    Synonyms
    1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-1-(2-propynyl)-3,5-pyridinedicarboxylic acid ethyl, methyl ester | 5-O-eth...
  3. Sodium Tanshinone IIA
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    Sodium Tanshinone IIA
    CAS: 69659-80-9 Formula: C19H17O6S · Na Molecular Weight: 396.39
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S107694
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    Technical Identifiers
    IUPAC Name
    sodium;1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-2-sulfonate
    SMILES
    CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)S(=O)(=O)[O-].[Na+]
    InChIKey
    AZEZEAABTDXEHR-UHFFFAOYSA-M
    InChI
    1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1
    Synonyms
    Danshen-201 | Sodium tanshinone II A sulfonate | TanshinoneIIA | SULFOTANSHINONE SODIUM II-A | DTXSID00219953 | TANSH...
  4. SKF-96365 hydrochloride
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    SKF-96365 hydrochloride
    CAS: 130495-35-1 PubChem CID: 104955 Formula: C22H26N2O3·HCl Molecular Weight: 402.92
    ≥98%
    In Stock Item #: S302342
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    Technical Identifiers
    IUPAC Name
    1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole;hydrochloride
    SMILES
    COC1=CC=C(C=C1)CCCOC(CN2C=CN=C2)C3=CC=C(C=C3)OC.Cl
    InChIKey
    FWLPKVQUECFKSW-UHFFFAOYSA-N
    InChI
    1S/C22H26N2O3.ClH/c1-25-20-9-5-18(6-10-20)4-3-15-27-22(16-24-14-13-23-17-24)19-7-11-21(26-2)12-8-19;/h5-14,17,22H,3-4,15-16H2,1-2H3;1H
    Synonyms
    S-175 | NCGC00260374-01 | CCG-268677 | 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl-1H-imidazole hydroc...
  5. 2-Aminoethyl diphenylborinate - Moligand™, ≥98% CAS No(524-95-8) by Aladdin Scientific
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    2-Aminoethyl diphenylborinate (2-APB), Channel blocker of TRPC1;Channel blocker of TRPC3;Channel blocker of TRPC4;Channel blocker of TRPC5;Channel blocker of TRPC6;Channel blocker of TRPC7;Channel blocker of TRPM2;Gating inhibitor of TRPM3;Activator of TRPM6;Activator of TRPM7;Channel blocker
    CAS: 524-95-8 EC Number: 208-366-5 Formula: C14H16BNO Molecular Weight: 225.09
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A106408
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    Technical Identifiers
    IUPAC Name
    2-diphenylboranyloxyethanamine
    SMILES
    B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN
    InChIKey
    BLZVCIGGICSWIG-UHFFFAOYSA-N
    InChI
    1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2
    Synonyms
    MFCD00014823 | SB79870 | BORINIC ACID, B,B-DIPHENYL-, 2-AMINOETHYL ESTER | 2-Aminoethyl diphenylborinate | C14H16BNO ...
  6. 4-(3,5-Bis(trifluoromethyl)-1h-pyrazol-1-yl)phenylamine
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    4-(3,5-Bis(trifluoromethyl)-1h-pyrazol-1-yl)phenylamine
    CAS: 123066-64-8 Formula: C11H7F6N3 Molecular Weight: 295.2
    ≥95%
    In Stock Item #: B180474
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    Technical Identifiers
    IUPAC Name
    4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]aniline
    SMILES
    C1=CC(=CC=C1N)N2C(=CC(=N2)C(F)(F)F)C(F)(F)F
    InChIKey
    XOXBUERZFCPKDR-UHFFFAOYSA-N
    InChI
    1S/C11H7F6N3/c12-10(13,14)8-5-9(11(15,16)17)20(19-8)7-3-1-6(18)2-4-7/h1-5H,18H2
    Synonyms
    A890856 | C11H7F6N3 | MLS000860231 | GS-4357 | 4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]aniline | Benzenamine, 4-[...
  7. 2-Aminoethyl diphenylborinate, Channel blocker of TRPC1;Channel blocker of TRPC3;Channel blocker of TRPC4;Channel blocker of TRPC5;Channel blocker of TRPC6;Channel blocker of TRPC7;Channel blocker of TRPM2;Gating inhibitor of TRPM3;Activator of TRPM6;Activator of TRPM7;Channel blocker
    Wish List Compare
    2-Aminoethyl diphenylborinate, Channel blocker of TRPC1;Channel blocker of TRPC3;Channel blocker of TRPC4;Channel blocker of TRPC5;Channel blocker of TRPC6;Channel blocker of TRPC7;Channel blocker of TRPM2;Gating inhibitor of TRPM3;Activator of TRPM6;Activator of TRPM7;Channel blocker
    CAS: 524-95-8 EC Number: 208-366-5 Formula: C14H16BNO Molecular Weight: 225.09
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A424505
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    Technical Identifiers
    IUPAC Name
    2-diphenylboranyloxyethanamine
    SMILES
    B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN
    InChIKey
    BLZVCIGGICSWIG-UHFFFAOYSA-N
    InChI
    1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2
    Synonyms
    MFCD00014823 | SB79870 | BORINIC ACID, B,B-DIPHENYL-, 2-AMINOETHYL ESTER | 2-Aminoethyl diphenylborinate | C14H16BNO ...
  8. CM 4620, Channel blocker of Orai1;Channel blocker of Orai2
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    CM 4620, Channel blocker of Orai1;Channel blocker of Orai2
    CAS: 1713240-67-5 Formula: C19H11ClF3N3O3 Molecular Weight: 421.76
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: C413652
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    Technical Identifiers
    IUPAC Name
    N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-2-fluoro-6-methylbenzamide
    SMILES
    CC1=C(C(=CC=C1)F)C(=O)NC2=NC=C(N=C2)C3=CC4=C(C=C3Cl)OC(O4)(F)F
    InChIKey
    QQMKTHUGOQDEIL-UHFFFAOYSA-N
    InChI
    1S/C19H11ClF3N3O3/c1-9-3-2-4-12(21)17(9)18(27)26-16-8-24-13(7-25-16)10-5-14-15(6-11(10)20)29-19(22,23)28-14/h2-8H,1H3,(H,25,26,27)
    Synonyms
    BS-15636 | CM 4620 | C73294 | BDBM50575336 | SCHEMBL18038390 | 564AW1RR37 | SB18686 | AC-35758 | CM4620 | CM-4620 | N...
  9. RO2959 hydrochloride
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    RO2959 hydrochloride
    CAS: 1219927-22-6 PubChem CID: 45274292 Formula: C21H20ClF2N5OS Molecular Weight: 463.93
    ≥98%
    In Stock Item #: R412934
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    Technical Identifiers
    IUPAC Name
    2,6-difluoro-N-[5-[4-methyl-1-(5-methyl-1,3-thiazol-2-yl)-3,6-dihydro-2H-pyridin-5-yl]pyrazin-2-yl]benzamide;hydrochloride
    SMILES
    CC1=C(CN(CC1)C2=NC=C(S2)C)C3=CN=C(C=N3)NC(=O)C4=C(C=CC=C4F)F.Cl
    InChIKey
    GMLSDODALBRLPE-UHFFFAOYSA-N
    InChI
    1S/C21H19F2N5OS.ClH/c1-12-6-7-28(21-26-8-13(2)30-21)11-14(12)17-9-25-18(10-24-17)27-20(29)19-15(22)4-3-5-16(19)23;/h3-5,8-10H,6-7,11H2,1-2H3,(H,25,27,show more
    Synonyms
    RO2959 HCl
  10. SKF-96365
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    SKF-96365
    CAS: 130495-35-1 EC Number: 634-170-8 PubChem CID: 104955 Formula: C22H26N2O3·HCl Molecular Weight: 402.92
    10mM in DMSO
    In Stock Item #: S421187
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    Technical Identifiers
    IUPAC Name
    1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole;hydrochloride
    SMILES
    COC1=CC=C(C=C1)CCCOC(CN2C=CN=C2)C3=CC=C(C=C3)OC.Cl
    InChIKey
    FWLPKVQUECFKSW-UHFFFAOYSA-N
    InChI
    1S/C22H26N2O3.ClH/c1-25-20-9-5-18(6-10-20)4-3-15-27-22(16-24-14-13-23-17-24)19-7-11-21(26-2)12-8-19;/h5-14,17,22H,3-4,15-16H2,1-2H3;1H
    Synonyms
    S-175 | NCGC00260374-01 | CCG-268677 | 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl-1H-imidazole hydroc...
  11. Sodium Tanshinone IIA
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    Sodium Tanshinone IIA
    CAS: 69659-80-9 Formula: C19H17O6S · Na Molecular Weight: 396.39
    10mM in DMSO
    In Stock Item #: S425575
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    sodium;1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-2-sulfonate
    SMILES
    CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)S(=O)(=O)[O-].[Na+]
    InChIKey
    AZEZEAABTDXEHR-UHFFFAOYSA-M
    InChI
    1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1
    Synonyms
    69659-80-9|sodium 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate|TANSHINONE II...
  12. YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
    Wish List Compare
    YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
    CAS: 223499-30-7 EC Number: 636-569-2 PubChem CID: 2455 Formula: C15H9F6N5OS Molecular Weight: 421.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: Y422686
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    Technical Identifiers
    IUPAC Name
    N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
    SMILES
    CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
    InChIKey
    XPRZIORDEVHURQ-UHFFFAOYSA-N
    InChI
    1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
    Synonyms
    HMS3648I22 | AS-16763 | CRAC Channel Inhibitor, BTP2 | SR-01000644222-3 | NCGC00344111-03 | AC-35791 | HMS3886H10 | I...
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