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Microsomal Triglyceride Transfer Protein (MTP)

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  1. Lomitapide
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    Lomitapide
    CAS: 182431-12-5 Formula: C39H37F6N3O2 Molecular Weight: 693.72
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: L168074
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    Technical Identifiers
    IUPAC Name
    N-(2,2,2-trifluoroethyl)-9-[4-[4-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]piperidin-1-yl]butyl]fluorene-9-carboxamide
    SMILES
    C1CN(CCC1NC(=O)C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)CCCCC4(C5=CC=CC=C5C6=CC=CC=C64)C(=O)NCC(F)(F)F
    InChIKey
    MBBCVAKAJPKAKM-UHFFFAOYSA-N
    InChI
    1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-1show more
    Synonyms
    AEGR-773 | BDBM50098320 | CHEBI:166515 | Lomitapide [USAN:INN] | 9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-...
  2. SLx-4090, Microsomal triglyceride transfer protein inhibitor
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    SLx-4090, Microsomal triglyceride transfer protein inhibitor
    CAS: 913541-47-6 PubChem CID: 53497429 Formula: C31H25F3N2O4 Molecular Weight: 546.54
    Solid ≥97%
    In Stock Item #: S178168
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    Technical Identifiers
    IUPAC Name
    phenyl 6-[[3-methoxy-2-[4-(trifluoromethyl)phenyl]benzoyl]amino]-3,4-dihydro-1H-isoquinoline-2-carboxylate
    SMILES
    COC1=CC=CC(=C1C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=CC4=C(CN(CC4)C(=O)OC5=CC=CC=C5)C=C3
    InChIKey
    AZUIUVJESCFSLJ-UHFFFAOYSA-N
    InChI
    1S/C31H25F3N2O4/c1-39-27-9-5-8-26(28(27)20-10-13-23(14-11-20)31(32,33)34)29(37)35-24-15-12-22-19-36(17-16-21(22)18-24)30(38)40-25-6-3-2-4-7-25/h2-15,1show more
    Synonyms
    KD-026 | KD026 | SLx4090 | SLx 4090
  3. Lomitapide Mesylate, Microsomal triglyceride transfer protein inhibitor
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    Lomitapide Mesylate, Microsomal triglyceride transfer protein inhibitor
    CAS: 202914-84-9 Formula: C40H41F6N3O5 Molecular Weight: 789.83
    10mM in DMSO
    Out of Stock Item #: L422469
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    Technical Identifiers
    IUPAC Name
    methanesulfonic acid;N-(2,2,2-trifluoroethyl)-9-[4-[4-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]piperidin-1-yl]butyl]fluorene-9-carboxamide
    SMILES
    CS(=O)(=O)O.C1CN(CCC1NC(=O)C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)CCCCC4(C5=CC=CC=C5C6=CC=CC=C64)C(=O)NCC(F)(F)F
    InChIKey
    QKVKOFVWUHNEBX-UHFFFAOYSA-N
    InChI
    1S/C39H37F6N3O2.CH4O3S/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)show more
    Synonyms
    AC-33863 | lomitapide methanesulfonate | CHEBI:72299 | N-(2,2,2-trifluoroethyl)-9-[4-(4-{2-[4-(trifluoromethyl)phenyl...
  4. Lomitapide
    Wish List Compare
    Lomitapide
    CAS: 182431-12-5 Formula: C39H37F6N3O2 Molecular Weight: 693.72
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: L422243
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-(2,2,2-trifluoroethyl)-9-[4-[4-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]piperidin-1-yl]butyl]fluorene-9-carboxamide
    SMILES
    C1CN(CCC1NC(=O)C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)CCCCC4(C5=CC=CC=C5C6=CC=CC=C64)C(=O)NCC(F)(F)F
    InChIKey
    MBBCVAKAJPKAKM-UHFFFAOYSA-N
    InChI
    1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-1show more
    Synonyms
    AEGR-773 | BDBM50098320 | CHEBI:166515 | Lomitapide [USAN:INN] | 9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-...
  5. Lomitapide Mesylate, Microsomal triglyceride transfer protein inhibitor
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    Lomitapide Mesylate, Microsomal triglyceride transfer protein inhibitor
    CAS: 202914-84-9 Formula: C40H41F6N3O5 Molecular Weight: 789.83
    ≥98%
    In Stock Item #: L413795
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    methanesulfonic acid;N-(2,2,2-trifluoroethyl)-9-[4-[4-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]piperidin-1-yl]butyl]fluorene-9-carboxamide
    SMILES
    CS(=O)(=O)O.C1CN(CCC1NC(=O)C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)CCCCC4(C5=CC=CC=C5C6=CC=CC=C64)C(=O)NCC(F)(F)F
    InChIKey
    QKVKOFVWUHNEBX-UHFFFAOYSA-N
    InChI
    1S/C39H37F6N3O2.CH4O3S/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)show more
    Synonyms
    AC-33863 | lomitapide methanesulfonate | CHEBI:72299 | N-(2,2,2-trifluoroethyl)-9-[4-(4-{2-[4-(trifluoromethyl)phenyl...
  6. Implitapide, Microsomal triglyceride transfer protein inhibitor
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    Implitapide, Microsomal triglyceride transfer protein inhibitor
    CAS: 177469-96-4 PubChem CID: 5745206 Formula: C35H37N3O2 Molecular Weight: 531.69
    ≥99%
    Out of Stock Item #: I648268
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    Technical Identifiers
    IUPAC Name
    (2S)-2-cyclopentyl-2-[3-[(2,4-dimethylpyrido[2,3-b]indol-9-yl)methyl]phenyl]-N-[(1R)-2-hydroxy-1-phenylethyl]acetamide
    SMILES
    CC1=CC(=NC2=C1C3=CC=CC=C3N2CC4=CC(=CC=C4)[C@H](C5CCCC5)C(=O)N[C@@H](CO)C6=CC=CC=C6)C
    InChIKey
    AMNXBQPRODZJQR-DITALETJSA-N
    InChI
    1S/C35H37N3O2/c1-23-19-24(2)36-34-32(23)29-17-8-9-18-31(29)38(34)21-25-11-10-16-28(20-25)33(27-14-6-7-15-27)35(40)37-30(22-39)26-12-4-3-5-13-26/h3-5,8show more
    Synonyms
    Implitapide [INN] | (2S)-2-cyclopentyl-2-(4-((2,4-dimethyl-9H-pyrido(2,3-b)indol-9-yl)methyl)phenyl)-N-((1S)-2-hydrox...
  7. CP-346086
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    CP-346086
    CAS: 186390-48-7 Formula: C26H22F3N5O Molecular Weight: 477.48
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: C649049
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    Technical Identifiers
    IUPAC Name
    N-[2-(1H-1,2,4-triazol-5-ylmethyl)-3,4-dihydro-1H-isoquinolin-6-yl]-2-[4-(trifluoromethyl)phenyl]benzamide
    SMILES
    C1CN(CC2=C1C=C(C=C2)NC(=O)C3=CC=CC=C3C4=CC=C(C=C4)C(F)(F)F)CC5=NC=NN5
    InChIKey
    WNDIAFXQKOHFLV-UHFFFAOYSA-N
    InChI
    1S/C26H22F3N5O/c27-26(28,29)20-8-5-17(6-9-20)22-3-1-2-4-23(22)25(35)32-21-10-7-19-14-34(12-11-18(19)13-21)15-24-30-16-31-33-24/h1-10,13,16H,11-12,14-1show more
    Synonyms
    CP346086Dihydrate | 4′-Trifluoromethyl-biphenyl-2-carboxylicacid[2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-...
  8. Dirlotapide
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    Dirlotapide
    CAS: 481658-94-0 PubChem CID: 9917862 Formula: C40H33F3N4O3 Molecular Weight: 674.71
    ≥99%
    Out of Stock Item #: D651112
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    Technical Identifiers
    IUPAC Name
    N-[(1S)-2-[benzyl(methyl)amino]-2-oxo-1-phenylethyl]-1-methyl-5-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]indole-2-carboxamide
    SMILES
    CN1C2=C(C=C(C=C2)NC(=O)C3=CC=CC=C3C4=CC=C(C=C4)C(F)(F)F)C=C1C(=O)NC(C5=CC=CC=C5)C(=O)N(C)CC6=CC=CC=C6
    InChIKey
    TUOSYWCFRFNJBS-BHVANESWSA-N
    InChI
    1S/C40H33F3N4O3/c1-46(25-26-11-5-3-6-12-26)39(50)36(28-13-7-4-8-14-28)45-38(49)35-24-29-23-31(21-22-34(29)47(35)2)44-37(48)33-16-10-9-15-32(33)27-17-1show more
    Synonyms
    Dirlotapide [USAN:INN] | Slentrol [veterinary] (TN) | Q5280905 | BDBM50204367 | D03867 | DB11399 | dirlotapida | dirl...
  12. CP-346086
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    CP-346086
    CAS: 186390-48-7 Formula: C26H22F3N5O Molecular Weight: 477.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: C1494818
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    Technical Identifiers
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