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Transthyretin (TTR)

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  1. A 1120, Inhibitor of retinol binding protein 4
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    A 1120, Inhibitor of retinol binding protein 4
    CAS: 1152782-19-8 Formula: C20H19F3N2O3 Molecular Weight: 392.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A288923
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    Technical Identifiers
    IUPAC Name
    2-[[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]amino]benzoic acid
    SMILES
    C1CN(CCC1C2=CC=CC=C2C(F)(F)F)C(=O)NC3=CC=CC=C3C(=O)O
    InChIKey
    MEAQCLPMSVEOQF-UHFFFAOYSA-N
    InChI
    1S/C20H19F3N2O3/c21-20(22,23)16-7-3-1-5-14(16)13-9-11-25(12-10-13)19(28)24-17-8-4-2-6-15(17)18(26)27/h1-8,13H,9-12H2,(H,24,28)(H,26,27)
    Synonyms
    GTPL8792 | HY-107633 | A 1120 | 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid | NCGC00...
  2. gamma-Mangostin
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    gamma-Mangostin
    CAS: 31271-07-5 Formula: C23H24O6 Molecular Weight: 396.43
    ≥98%(HPLC)
    In Stock Item #: G169488
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    IUPAC Name
    1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one
    SMILES
    CC(=CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C(=C(C(=C3)O)O)CC=C(C)C)O)C
    InChIKey
    VEZXFTKZUMARDU-UHFFFAOYSA-N
    InChI
    1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3
    Synonyms
    9H-Xanthen-9-one, 1,3,6,7-tetrahydroxy-2,8-bis(3-methyl-2-butenyl)- | PDSP2_000060 | SCHEMBL3753526 | BDBM50241453 | ...
  3. Tafamidis, Transthyretin stabiliser
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    Tafamidis, Transthyretin stabiliser
    CAS: 594839-88-0 EC Number: 813-715-5 PubChem CID: 11001318 Formula: C14H7Cl2NO3 Molecular Weight: 308.12
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: T424958
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    Technical Identifiers
    IUPAC Name
    2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
    SMILES
    C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
    InChIKey
    TXEIIPDJKFWEEC-UHFFFAOYSA-N
    InChI
    1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)
    Synonyms
    TAFAMIDIS|594839-88-0|Vyndamax|FX-1006|2-(3,5-Dichlorophenyl)-1,3-Benzoxazole-6-Carboxylic Acid|tafamidisum|2-(3,5-Di...
  4. Tafamidis, Transthyretin stabiliser
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    Tafamidis, Transthyretin stabiliser
    CAS: 594839-88-0 EC Number: 813-715-5 PubChem CID: 11001318 Formula: C14H7Cl2NO3 Molecular Weight: 308.12
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: T413467
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    Technical Identifiers
    IUPAC Name
    2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
    SMILES
    C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
    InChIKey
    TXEIIPDJKFWEEC-UHFFFAOYSA-N
    InChI
    1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)
    Synonyms
    AKOS017550076 | Tafamidis [USAN] | DTXCID20130676 | FX-1005 | TAFAMIDIS [MI] | BDBM50197883 | s6465 | 6-Benzoxazoleca...
  5. WAY-300033
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    WAY-300033
    CAS: 23983-05-3 PubChem CID: 689165 Formula: C16H9ClN2OS Molecular Weight: 312.77
    10mM in DMSO
    In Stock Item #: W422800
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    Technical Identifiers
    IUPAC Name
    (2Z)-2-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one
    SMILES
    C1=CC=C(C(=C1)C=C2C(=O)N3C4=CC=CC=C4N=C3S2)Cl
    InChIKey
    LSMPFFSYANAQSU-ZROIWOOFSA-N
    InChI
    1S/C16H9ClN2OS/c17-11-6-2-1-5-10(11)9-14-15(20)19-13-8-4-3-7-12(13)18-16(19)21-14/h1-9H/b14-9-
    Synonyms
    2-(2-Chlorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one | HY-153577 | Thiazolo(3,2-a)benzimidazol-3(2H)-one,...
  6. WAY-300033
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    WAY-300033
    CAS: 23983-05-3 PubChem CID: 689165 Formula: C16H9ClN2OS Molecular Weight: 312.77
    ≥98%
    In Stock Item #: W416818
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    Technical Identifiers
    IUPAC Name
    (2Z)-2-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one
    SMILES
    C1=CC=C(C(=C1)C=C2C(=O)N3C4=CC=CC=C4N=C3S2)Cl
    InChIKey
    LSMPFFSYANAQSU-ZROIWOOFSA-N
    InChI
    1S/C16H9ClN2OS/c17-11-6-2-1-5-10(11)9-14-15(20)19-13-8-4-3-7-12(13)18-16(19)21-14/h1-9H/b14-9-
    Synonyms
    2-(2-Chlorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one | HY-153577 | Thiazolo(3,2-a)benzimidazol-3(2H)-one,...
  7. Inotersen sodium
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    Inotersen sodium
    CAS: 1432726-13-0 PubChem CID: 121493436 Molecular Weight: 7601.00
    ≥93%
    Out of Stock Item #: I647785
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    Technical Identifiers
    SMILES
    CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=S)([O-])O[C@H]3C[C@@H](O[C@@H]3COP(=S)([O-])O[C@H]4C[C@@H](O[C@@H]4COP(=S)([O-])O[C@@H]5[C@H](O[C@H]([C@show more
  9. Acoramidis hydrochloride
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    Acoramidis hydrochloride
    CAS: 2242751-53-5 PubChem CID: 135307127 Formula: C15H18ClFN2O3 Molecular Weight: 328.77
    ≥98%
    Out of Stock Item #: A646727
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    IUPAC Name
    3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid;hydrochloride
    SMILES
    CC1=C(C(=NN1)C)CCCOC2=C(C=CC(=C2)C(=O)O)F.Cl
    InChIKey
    MGFZEARHINUOMX-UHFFFAOYSA-N
    InChI
    1S/C15H17FN2O3.ClH/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16;/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20);1H
    Synonyms
    Acoramidis hydrochloride [USAN] | UNII-VY9C88C2NV | Acoramidis (hydrochloride) | Alxn2060 hydrochloride | Alxn-2060 h...
  10. Dichlorophenyl-ABA
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    Dichlorophenyl-ABA
    CAS: 18201-65-5 PubChem CID: 644279 Formula: C13H9Cl2NO2 Molecular Weight: 282.12
    ≥99%
    Out of Stock Item #: D648506
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    Technical Identifiers
    IUPAC Name
    2-(3,5-dichloroanilino)benzoic acid
    SMILES
    C1=CC=C(C(=C1)C(=O)O)NC2=CC(=CC(=C2)Cl)Cl
    InChIKey
    FNGSQOJHNAYHAT-UHFFFAOYSA-N
    InChI
    1S/C13H9Cl2NO2/c14-8-5-9(15)7-10(6-8)16-12-4-2-1-3-11(12)13(17)18/h1-7,16H,(H,17,18)
    Synonyms
    benzoic acid, 2-[(3,5-dichlorophenyl)amino]- | benzoic acid,2-[(3,5-dichlorophenyl)amino]- | 2-[(3,5-dichlorophenyl)a...
  11. Tafamidis meglumine, Transthyretin stabiliser
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    Tafamidis meglumine, Transthyretin stabiliser
    CAS: 951395-08-7 EC Number: 813-716-0 Formula: C21H24Cl2N2O8 Molecular Weight: 503.33
    ≥99%
    In Stock Item #: T651781
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    Technical Identifiers
    IUPAC Name
    2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
    SMILES
    CNCC(C(C(C(CO)O)O)O)O.C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
    InChIKey
    DQJDBUPLRMRBAB-WZTVWXICSA-N
    InChI
    1S/C14H7Cl2NO3.C7H17NO5/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-6H,(H,18,19);4-13H,2-3H2,1H3/t;4-show more
    Synonyms
    Tafamidis meglumine | Vyndaqel | (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol 2-(3,5-dichlorophenyl)benzo[d]...
  12. 3-[3-(3,5-Dimethyl-1h-Pyrazol-4-Yl)propoxy]-4-Fluorobenzoic Acid, Transthyretin stabiliser
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    3-[3-(3,5-Dimethyl-1h-Pyrazol-4-Yl)propoxy]-4-Fluorobenzoic Acid, Transthyretin stabiliser
    CAS: 1446711-81-4 PubChem CID: 71464713 Formula: C15H17FN2O3 Molecular Weight: 292.3
    Out of Stock Item #: D671270
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    Technical Identifiers
    IUPAC Name
    3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid
    SMILES
    CC1=C(C(=NN1)C)CCCOC2=C(C=CC(=C2)C(=O)O)F
    InChIKey
    WBFUHHBPNXWNCC-UHFFFAOYSA-N
    InChI
    1S/C15H17FN2O3/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20)
    Synonyms
    Acoramidis | 4hiq | 3-[3-(3,5-Dimethyl-1h-Pyrazol-4-Yl)propoxy]-4-Fluorobenzoic Acid | HY-109165 | AG10 | SCHEMBL1581...
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