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Glucocorticoid Receptor

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  1. GSK 9027
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    GSK 9027
    CAS: 1229096-88-1 Formula: C27H19F4N3O2S Molecular Weight: 525.52
    ≥98%(HPLC)
    In Stock Item #: G288349
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    Technical Identifiers
    IUPAC Name
    N-[4-[1-(4-fluorophenyl)indazol-5-yl]-3-(trifluoromethyl)phenyl]-1-phenylmethanesulfonamide
    SMILES
    C1=CC=C(C=C1)CS(=O)(=O)NC2=CC(=C(C=C2)C3=CC4=C(C=C3)N(N=C4)C5=CC=C(C=C5)F)C(F)(F)F
    InChIKey
    DXBJGDVBQPEMOB-UHFFFAOYSA-N
    InChI
    1S/C27H19F4N3O2S/c28-21-7-10-23(11-8-21)34-26-13-6-19(14-20(26)16-32-34)24-12-9-22(15-25(24)27(29,30)31)33-37(35,36)17-18-4-2-1-3-5-18/h1-16,33H,17H2
    Synonyms
    N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide
  2. Fluticasone propionate-d5
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    Fluticasone propionate-d5
    CAS: 1093258-28-6 Formula: C25H26F3O5SD5 Molecular Weight: 505.61
    ≥92%,≥95 atom% D
    Out of Stock Item #: F336070
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    Technical Identifiers
    IUPAC Name
    [(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocshow more
    SMILES
    CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF
    InChIKey
    WMWTYOKRWGGJOA-AMTWIDTLSA-N
    InChI
    1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8show more
    Synonyms
    [(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-ox...
  3. Corticosterone, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor
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    Corticosterone, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor
    CAS: 50-22-6 EC Number: 200-019-6 Formula: C21H30O4 Molecular Weight: 346.46
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    In Stock Item #: C119329
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    Technical Identifiers
    IUPAC Name
    (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
    SMILES
    CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C)O
    InChIKey
    OMFXVFTZEKFJBZ-HJTSIMOOSA-N
    InChI
    1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,2show more
    Synonyms
    (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydroc...
  4. Loteprednol etabonate, Glucocorticoid receptor agonist
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    Loteprednol etabonate, Glucocorticoid receptor agonist
    CAS: 82034-46-6 Formula: C24H31ClO7 Molecular Weight: 466.95
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: L129196
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    Technical Identifiers
    IUPAC Name
    chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrshow more
    SMILES
    CCOC(=O)OC1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)C(=O)OCCl
    InChIKey
    DMKSVUSAATWOCU-HROMYWEYSA-N
    InChI
    1S/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1show more
    Synonyms
    HGP 1 | (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-...
  5. 6α-Methylprednisolone 21-hemisuccinate sodium salt, Glucocorticoid receptor agonist
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    6α-Methylprednisolone 21-hemisuccinate sodium salt, Glucocorticoid receptor agonist
    CAS: 2375-03-3 Formula: C26H33NaO8 Molecular Weight: 496.53
    ≥98%
    In Stock Item #: M168895
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    Technical Identifiers
    IUPAC Name
    sodium;4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-show more
    SMILES
    CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)[O-])O.[Na+]
    InChIKey
    FQISKWAFAHGMGT-SGJOWKDISA-M
    InChI
    1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33show more
    Synonyms
    AfAE'Adaggeratrade mark?-Methylprednisolone 21-hemisuccinate (sodium salt) | M-6-P | Omnacortil | HY-B1060 | METHYLPR...
  6. Betamethasone 17-valerate, Glucocorticoid receptor agonist
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    Betamethasone 17-valerate, Glucocorticoid receptor agonist
    CAS: 2152-44-5 EC Number: 218-439-3 Formula: C27H37FO6 Molecular Weight: 476.58
    ≥98%
    In Stock Item #: B123298
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    Technical Identifiers
    IUPAC Name
    [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthshow more
    SMILES
    CCCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CO
    InChIKey
    SNHRLVCMMWUAJD-SUYDQAKGSA-N
    InChI
    1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,1show more
    Synonyms
    Fuciderm | Topagen (Veterinary) | betamethasone-valerate | Bettamousse | 9-Fluoro-11-beta,17,21-trihydroxy-16-beta-me...
  7. Medroxyprogesterone acetate - Moligand™, ≥98% CAS No(71-58-9) by Aladdin Scientific
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    Medroxyprogesterone acetate, Progesterone receptor agonist
    CAS: 71-58-9 EC Number: 200-757-9 Formula: C24H34O4 Molecular Weight: 386.52
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M129409
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    Technical Identifiers
    IUPAC Name
    [(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
    SMILES
    CC1CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C
    InChIKey
    PSGAAPLEWMOORI-PEINSRQWSA-N
    InChI
    1S/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23show more
    Synonyms
    Clinovir | DP150 | Medroxyprogesterone acetate (Standard) | Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6alpha...
  8. Hydrocortisone - Moligand™, ≥98%, CAS No. 50-23-7 by
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    Hydrocortisone, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor
    CAS: 50-23-7 EC Number: 200-020-1 Formula: C21H30O5 Molecular Weight: 362.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: H110523
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    Technical Identifiers
    IUPAC Name
    (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
    SMILES
    CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
    InChIKey
    JYGXADMDTFJGBT-VWUMJDOOSA-N
    InChI
    1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+show more
    Synonyms
    Cortisporin Otico | Evacort | Barseb HC | Cortenema | Penecort | Permicort | Synacort | Epiderm H | Polcort H | Timoc...
  9. Betamethasone 17,21-Dipropionate, Glucocorticoid receptor agonist
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    Betamethasone 17,21-Dipropionate, Glucocorticoid receptor agonist
    CAS: 5593-20-4 EC Number: 227-005-2 Formula: C28H37FO7 Molecular Weight: 504.59
    ≥97%
    In Stock Item #: B123297
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    Technical Identifiers
    IUPAC Name
    [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthreshow more
    SMILES
    CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CC
    InChIKey
    CIWBQSYVNNPZIQ-XYWKZLDCSA-N
    InChI
    1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-show more
    Synonyms
    Betamethasone (as dipropionate) | BETAMETHASONE DIPROPIONATE [GREEN BOOK] | KS-5303 | PREGNA-1,4-DIENE-3,20-DIONE, 9-...
  10. Deflazacort
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    Deflazacort
    CAS: 14484-47-0 EC Number: 238-483-7 Formula: C25H31NO6 Molecular Weight: 441.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: D129585
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    Technical Identifiers
    IUPAC Name
    [2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,9,13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-8-yl]-2-oxoethylshow more
    SMILES
    CC1=NC2(C(O1)CC3C2(CC(C4C3CCC5=CC(=O)C=CC45C)O)C)C(=O)COC(=O)C
    InChIKey
    FBHSPRKOSMHSIF-GRMWVWQJSA-N
    InChI
    1S/C25H31NO6/c1-13-26-25(20(30)12-31-14(2)27)21(32-13)10-18-17-6-5-15-9-16(28)7-8-23(15,3)22(17)19(29)11-24(18,25)4/h7-9,17-19,21-22,29H,5-6,10-12H2,1show more
    Synonyms
    LS-13240 | DEFLAZACORT (MART.) | Deflazacort, United States Pharmacopeia (USP) Reference Standard | T70289 | Deflazac...
  11. Prednisolone disodium phosphate, Glucocorticoid receptor agonist
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    Prednisolone disodium phosphate, Glucocorticoid receptor agonist
    CAS: 125-02-0 PubChem CID: 441409 Formula: C21H27Na2O8P Molecular Weight: 484.39
    ≥98%(HPLC)
    In Stock Item #: D155760
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    Technical Identifiers
    IUPAC Name
    disodium;[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoeshow more
    SMILES
    CC12CC(C3C(C1CCC2(C(=O)COP(=O)([O-])[O-])O)CCC4=CC(=O)C=CC34C)O.[Na+].[Na+]
    InChIKey
    VJZLQIPZNBPASX-OJJGEMKLSA-L
    InChI
    1S/C21H29O8P.2Na/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-29-30(26,27)28)20(15,2)10-16(23)18(14)19;;/h5,7,9,14-16,18,23,25H,3-4,6,8,10-11Hshow more
    Synonyms
    2-Chloro-4-pyridinylboronic acid, >=95.0% | D3918 | 11.BETA.,17,21-TRIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE 21-(DISODIUM...
  12. Prednisolone hemisuccinate
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    Prednisolone hemisuccinate
    CAS: 2920-86-7 PubChem CID: 656804 Formula: C25H32O8 Molecular Weight: 460.52
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P303338
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-show more
    SMILES
    CC12CC(C3C(C1CCC2(C(=O)COC(=O)CCC(=O)O)O)CCC4=CC(=O)C=CC34C)O
    InChIKey
    APGDTXUMTIZLCJ-CGVGKPPMSA-N
    InChI
    1S/C25H32O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h7,9,11,16-18,22,27,32H,3-6,8,10,12show more
    Synonyms
    Prednisolone 21-(hydrogen succinate) | PREDNISOLONE HEMISUCCINATE
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