Determine the necessary mass, volume, or concentration for preparing a solution.
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≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
application:
Lomefloxacin is a fluoroquinolone antibiotic that is commonly used to treat bacterial infections, including bronchitis and urinary tract infections. It is used to induce genomic instability in mice and modification of the kinetics of growth of Gram-negative bacteria.
| Pubchem Sid | 504754300 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504754300 |
| Canonical Smiles | CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl |
| IUPAC Name | 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;hydrochloride |
| InChIKey | KXEBLAPZMOQCKO-UHFFFAOYSA-N |
| INCHI | 1S/C17H19F2N3O3.ClH/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);1H |
| Isomeric SMILES | CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl |
| WGK Germany | 3 |
| RTECS | VB1997500 |
| Molecular Weight | 387.81 |
| Reaxy-Rn | 7506829 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7506829&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Quinolines and derivatives |
| Subclass | Quinoline carboxylic acids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Quinoline carboxylic acids |
| Alternative Parents | N-arylpiperazines Fluoroquinolones Aminoquinolines and derivatives Hydroquinolones Haloquinolines Hydroquinolines Pyridinecarboxylic acids Dialkylarylamines Aryl fluorides Benzenoids Vinylogous amides Heteroaromatic compounds Amino acids Azacyclic compounds Carboxylic acids Dialkylamines Monocarboxylic acids and derivatives Organooxygen compounds Organic oxides Organofluorides Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Quinoline-3-carboxylic acid - Fluoroquinolone - N-arylpiperazine - Aminoquinoline - Haloquinoline - Dihydroquinolone - Dihydroquinoline - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Benzenoid - Aryl fluoride - Aryl halide - Pyridine - 1,4-diazinane - Piperazine - Heteroaromatic compound - Vinylogous amide - Tertiary amine - Amino acid - Amino acid or derivatives - Azacycle - Secondary amine - Carboxylic acid derivative - Carboxylic acid - Secondary aliphatic amine - Monocarboxylic acid or derivatives - Organopnictogen compound - Organic oxygen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Hydrochloride - Organohalogen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions. |
| External Descriptors | hydrochloride |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Oct 30, 2025 | L103102 | |
| Certificate of Analysis | Oct 30, 2025 | L103102 | |
| Certificate of Analysis | Oct 30, 2025 | L103102 | |
| Certificate of Analysis | Apr 08, 2025 | L103102 | |
| Certificate of Analysis | Feb 08, 2023 | L103102 | |
| Certificate of Analysis | Dec 30, 2021 | L103102 | |
| Certificate of Analysis | Dec 30, 2021 | L103102 | |
| Certificate of Analysis | Dec 30, 2021 | L103102 |
| Molecular Weight | 387.800 g/mol |
|---|---|
| XLogP3 | |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 3 |
| Exact Mass | 387.116 Da |
| Monoisotopic Mass | 387.116 Da |
| Topological Polar Surface Area | 72.900 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 585.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
| 1. Guangli Li, Xiaoman Qi, Jingtao Wu, Xuan Wan, Tianyu Wang, Ying Liu, Yuwei Chen, Yonghui Xia. (2023) Highly stable electrochemical sensing platform for the selective determination of pefloxacin in food samples based on a molecularly imprinted-polymer-coated gold nanoparticle/black phosphorus nanocomposite. FOOD CHEMISTRY, [PMID:37862994] [10.1016/j.foodchem.2023.137753] |
| 2. Xiao-Bing Zheng, Sheng-Hong Liu, Bao-Ying Wen, Wei Peng, Hong-Mei Li, Murugavel Kathiresan, Yue-Jiao Zhang, Shang-Zhong Jin, Jian-Feng Li. (2023) Rapid detection and whole class control of quinolone antibiotics in pork based on surface-enhanced Raman spectroscopy. JOURNAL OF RAMAN SPECTROSCOPY, 54 (5): (468-476). [PMID:] [10.1002/jrs.6509] |
| 3. Leliang Wu, Yiting Lin, Yimin Zhang, Peng Wang, Mingjun Ding, Minghua Nie, Caixia Yan, Shiyao Chen. (2021) Ca(OH)2-mediated activation of peroxymonosulfate for the degradation of bisphenol S. RSC Advances, 11 (53): (33626-33636). [PMID:35497526] [10.1039/D1RA05286A] |
| 4. Xie Yizhen, Li Qiuyi, Qin Lulu, Zhou Xiaobin, Fan Yinming. (2021) Multi-templates surface molecularly imprinted polymer for simultaneous and rapid determination of sulfonamides and quinolones in water: effect of carbon-carbon double bond. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 28 (39): (54950-54959). [PMID:34120285] [10.1007/s11356-021-14794-6] |
| 5. Jiaxing Huang, Daguang Li, Ruobai Li, Qianxin Zhang, Tiansheng Chen, Haijin Liu, Yang Liu, Wenying Lv, Guoguang Liu. (2019) An efficient metal-free phosphorus and oxygen co-doped g-C3N4 photocatalyst with enhanced visible light photocatalytic activity for the degradation of fluoroquinolone antibiotics. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.05.175] |
| 6. Yan Zhao, Lianfang Chen, Fenglin Tang, Lilei Zhang, Qiang Yang, Xiupei Yang. (2025) Boosting peroxymonosulfate activation for complete removal of gatifloxacin by a bead-chain zeolitic imidazolate framework composite. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:39837247] [10.1016/j.jcis.2025.01.102] |
| 7. Wenhui Ai, Ge Chen, Jiayao Chen, Yao Jin, Xiufeng Wang, Ting Zhou, Zhiqing Zhang, Fang Wang, Guodong Zhang. (2024) Cu-MoOx-based nanozyme with enhanced peroxidase like activity for quinolone antibiotics detection. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:39288602] [10.1016/j.saa.2024.125117] |
| 8. Jingtao Wu, Yonghui Xia, Tianyu Wang, Yafeng Zhang, Guangli Li. (2024) Efficient voltammetric platform combining a molecularly imprinted polymer and silver-nanoparticle-decorated black phosphorus nanosheets for selective determination of Gatifloxacin. Food Chemistry-X, [PMID:39758065] [10.1016/j.fochx.2024.102094] |
| 9. Furong Tang, Ting Zou, Ziyi Wang, Juan Zhang. (2024) Fabrication of fluorinated triazine-based covalent organic frameworks for selective extraction of fluoroquinolone in milk. JOURNAL OF CHROMATOGRAPHY A, [PMID:38889582] [10.1016/j.chroma.2024.465078] |
| 10. Zhaofeng Wang, Hui Xu, Lihua Wang, Xinxiang Zheng, Tengzhi Zhao, Bowen Qu, Hua Wang. (2025) Highly-sensitive ratiometric determination of tetracyclines and smartphone-assisted visual assay by carrot-derived nitrogen-doped carbon dots-europium ion dual-emission fluorescence probe. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.113398] |
| 11. Fuhua Wei, Jie Gong, Qinhui Ren, Xiang Yu, Yan Wang, Hongliang Chen, Zhao Liang. (2024) Preparation of Zn/Zr-MOFs by microwave-assisted ball milling and adsorption of lomefloxacin hydrochloride and levofloxacin hydrochloride in wastewater. ENVIRONMENTAL RESEARCH, [PMID:38649015] [10.1016/j.envres.2024.118941] |
| 12. Huang Xiao-Qing, Wang Mao-Yu, Wang Xiao-Chen, Shi Xin, Li Rui-Wen, Wu Shuang, Li Ying. (2025) A surface-imprinting lanthanide fluorescent hybrid probe on SiO2 microspheres for the detection of enrofloxacin. MICROCHIMICA ACTA, 192 (8): (1-12). [PMID:40731103] [10.1007/s00604-025-07369-6] |
| 13. Tao Peng, Zhanwei Liang, Jinxue Zhao, Jihao Si, Jie Xie, Xinhua Dai, Lidong Wu. (2025) Terbium (III) and adenosine monophosphate coordinated hydrogel for fluoroquinolones sensing by combining machine learning. FOOD CHEMISTRY, [PMID:40907184] [10.1016/j.foodchem.2025.146115] |
| 14. Zhao Tengzhi, Wang Zhaofeng, Zhang Runke, Xu Hui, Wang Hua, Yu Ying. (2025) Carrot-Derived Nitrogen-Doped Dual-Emission Carbon Dots for Ratiometric Detection of Tetracycline and Oxytetracycline. JOURNAL OF FLUORESCENCE, [PMID:40924358] [10.1007/s10895-025-04531-4] |
| 15. Kaichun Lin, Jingjun Qin, Zhang Liu, Weicheng Xu, Meng Li, Yuanzhi Zheng, Wei Han, Guangying Zhou, Jianzhang Fang, Zhanqiang Fang, Feng Peng, King Lun Yeung. (2025) Cobalt-Modification on UiO-bpydc MOF Facilitates Ligand-to-Metal Charge Transfer for Superior Visible-Light Photocatalytic Degradation of Refractory Fluoroquinolone Antibiotics. ENVIRONMENTAL RESEARCH, [PMID:40345418] [10.1016/j.envres.2025.121789] |