Metolazone - Moligand™, 10mM in DMSO , Thiazide-sensitive sodium-chloride cotransporter inhibitor, CAS No.17560-51-9, Thiazide-sensitive sodium-chloride cotransporter inhibitor

CAS: 17560-51-9 Cat. No.: M408779 Molecular Weight: 365.83 EC Number: 241-539-3

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

SR 720-22 | 7-​chloro-​1,​2,​3,​4-​tetrahydro-​2-​methyl-​3-​(2-​methylphenyl)​-​4-​oxo-6-​quinazolinesulfonami​de

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Metolazone (SR 720-22) is a diuretic that primarily used to treat congestive heart failure and high blood pressure.
In vitro

In vivo

Cell Data

cell lines：MM-1S, MM-1R, RPMI-8226/S, OPM-1, OCI-My5, SKMM2, KMS-12-BM, XG-1, L363, S6B45 cells and et al.

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

SR 720-22 | 7-​chloro-​1, ​2, ​3, ​4-​tetrahydro-​2-​methyl-​3-​(2-​methylphenyl)​-​4-​oxo-6-​quinazolinesulfonami​de

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Metolazone (SR 720-22) is a diuretic that primarily used to treat congestive heart failure and high blood pressure.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Mechanism of action

Thiazide-sensitive sodium-chloride cotransporter inhibitor

Product Properties

• ALogP: 4.1

Names and Identifiers

• Isomeric SMILES: CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl
• Molecular Weight: 365.83
• Reaxy-Rn: 965506
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=965506&ln=

Associated Targets(Human)

CA7 Tclin Carbonic anhydrase 7 (1 Activities)

Discover Target: CA7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)