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MI-3 - Moligand™, ≥98% , CAS No.1271738-59-0

MI-3 - Moligand™, ≥98% , CAS No.1271738-59-0

CAS: 1271738-59-0 Cat. No.: M125633 Molecular Weight: 375.55 PubChem CID: 51001299

COA

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? ≥98%

Synonyms

Menin-MLL inhibitor 3 | 4-(4-(5,5-dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-isopropylthieno[2,3-d]pyrimidine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications Names and Identifiers Documentation Advanced Data Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms

Menin-MLL inhibitor 3 | 4-(4-(5, 5-dimethyl-4, 5-dihydrothiazol-2-yl)piperazin-1-yl)-6-isopropylthieno[2, 3-d]pyrimidine

Specifications & Purity

Moligand™, ≥98%

Biochemical and Physiological Mechanisms

MI-3 is Menin-MLL inhibitor, inhibitors of the menin-MLL fusion protein interaction that specifically bind menin with nanomolar affinities.Potent menin-MLL\xa0interaction inhibitor (IC 50 of 648 nM). Inhibits the menin-MLL-AF9 interaction in HEK-293 cells

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Note

Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%

Names and Identifiers

Pubchem Sid	504770999
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504770999
Isomeric SMILES	CC(C)C1=CC2=C(N=CN=C2S1)N3CCN(CC3)C4=NCC(S4)(C)C
PubChem CID	51001299
Molecular Weight	375.55

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)

MEN1 Tchem Menin (1 Activities)

Discover Target: MEN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HepG2 (196354 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MEN1 Tchem Menin (447 Activities)

Discover Target: MEN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
C2619176	Certificate of Analysis	Mar 30, 2026	M125633
K2527145	Certificate of Analysis	Dec 05, 2025	M125633
C2303643	Certificate of Analysis	Dec 06, 2024	M125633
C2303646	Certificate of Analysis	Dec 06, 2024	M125633
C2303653	Certificate of Analysis	Dec 06, 2024	M125633
C2303655	Certificate of Analysis	Dec 06, 2024	M125633

Chemical and Physical Properties

Solubility	DMSO
Molecular Weight	375.600 g/mol
XLogP3	3.700
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	375.155 Da
Monoisotopic Mass	375.155 Da
Topological Polar Surface Area	98.200 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	516.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Solution Calculators

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Reviews

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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

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