Microcrystalline Cellulose and Carboxymethylcellulose Sodium - Ph.Eur., E 460(i), E 466, NF

Cat. No.: M498254
AVAILABLE TO ORDER
Only %1 left
GRADE & PURITY Ph.Eur. ? European Pharmacopoeia grade — conforms to Ph.Eur. monographs across EU member states. Use for pharmaceutical work needing European compendial compliance. E 460(i) ? EU food-additive code E 460(i) — this product corresponds to microcrystalline cellulose. The E-number signals it meets the identity/spec expected for that additive in food-contact use. E 466 ? EU food-additive code E 466 — this product corresponds to carboxymethyl cellulose. The E-number signals it meets the identity/spec expected for that additive in food-contact use. NF ? National Formulary grade — meets NF monograph standards, often for excipients. Use for pharmaceutical excipients and products requiring NF compliance.
Storage
Room temperature
Shipped In
Normal
Price
As low as $148.90 Regular Price $148.90
AVAILABLE TO ORDER

Overview

M498254 is a synergistic, co-processed composite consisting of microcrystalline cellulose (MCC) and sodium carboxymethylcellulose (Na-CMC). It is a unique suspending and emulsifying agent, which facilitates a wide range of liquid dosage forms. Due to its extraordinary stabilizing mechanism, M498254 can be used with a broad variety of active pharmaceutical ingredients (APIs), offering the opportunity for new applications and line extensions for existing products.

M498254 is a free flowing powder. After activation, MCG builds an opaque-white dispersion which masks insoluble particles, giving the suspension a homogenous appearance. The dispersed M498254 is distinguished by an odorless and tasteless, smooth but not slimy mouth feel, and handles flavors well. Upon agitation, MCG dispersions show a time-dependent decrease in viscosity and become liquid. A complete, also time-dependent, regeneration of the viscosity takes place during a subsequent rest period. 


Benefits:

1.Easy handling of dry powder

2.Heat stability

3.Compatibility with a wide range of ingredients

4.Stable over a wide pH range

5.Safe for us in animal health products, pediatric 6.suspensions, and nutraceuti


Product specifications and parameters:

SKU

NaCMC (%)

Particle Size

Viscosity
(mPa.s)

Main Application

Pack Size

M498254-581P-500g

8.3 – 13.8

>250 µm (60 mesh):
max. 0.1%
>75 µm (200 mesh):
max. 35%

72 – 168
(1.2% solids)

For "ready-to-use" suspensions and emulsion prepared with high shear forces.

500g

M498254-591P-500g

8.3 – 13.8

>250 µm (60 mesh):
max. 0.1%
>45 µm (325 mesh):
max. 45%

39 – 91
(1.2% solids)

 

500g

M498254-611P-500g

11.3 – 18.8

>250 µm (60 mesh):
max. 0.1%
>45 µm (325 mesh):
max. 50%

50 – 118
(2.6% solids)

For reconstitutable dry suspensions.

500g

M498254-811P-500g

11.3 – 18.8

>250 µm (60 mesh):
max. 3%

2400 – 5600
(2.6% solids)

Highly effective dispersible cellulose grade for a variety of suspensions, emulsions, and spray applications.

500g


Specifications

Specifications & Purity
Ph.Eur., E 460(i), E 466, NF
Storage
Room temperature
Shipped In
Normal
Grade
E 460(i), E 466, NF, Ph.Eur.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
J2430489Certificate of AnalysisJul 04, 2024 M498254
J2430490Certificate of AnalysisJul 04, 2024 M498254
H2428229Certificate of AnalysisMay 17, 2024 M498254
H2428232Certificate of AnalysisMay 17, 2024 M498254
H2428233Certificate of AnalysisMay 17, 2024 M498254
H2428249Certificate of AnalysisMay 17, 2024 M498254
H2428250Certificate of AnalysisMay 17, 2024 M498254
H2402648Certificate of AnalysisApr 16, 2024 M498254
H2402649Certificate of AnalysisApr 16, 2024 M498254
Chemical and Physical Properties
SensitivityHeat and moisture sensitive
Documents & Articles
Solution Calculators
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