N-Decanoyl-N-methylglucamine - High-purity , CAS No.85261-20-7

CAS: 85261-20-7 Cat. No.: D112864 Molecular Weight: 349.46 Beilstein Registry Number: 6974359

GRADE & PURITY High-purity

Synonyms

N-DECANOYL-N-METHYL-1-AMINO-1-DEOXY-D-GLUCITOL | N-Methyl-N-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)decanamide | N-Decanoyl-N-methyl-D-glucamine | A863630 | N-(D-Glucityl)-N-methyldecanamide | Decanoyl N-methylglucamide | SCHEMBL61278 | N-METHYL-N-DECA

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

Product Describtion:

Acyl-N-methylglucamide (MEGA) detergents are non-ionic detergents that provide a good starting point for your structural biology work. The hydrophilic head groups offer ample strength to extract proteins while still providing the capability to stabilize proteins in solution and promote crystal growth.MEGA-10/N-decanoyl-N-methylglucamine is a longer carbon chain or a sugar-based surfactant. It is a member of the fatty acid glucamides family.

Specifications

Synonyms

N-DECANOYL-N-METHYL-1-AMINO-1-DEOXY-D-GLUCITOL | N-Methyl-N-((2S, 3R, 4R, 5R)-2, 3, 4, 5, 6-pentahydroxyhexyl)decanamide | N-Decanoyl-N-methyl-D-glucamine | A863630 | N-(D-Glucityl)-N-methyldecanamide | Decanoyl N-methylglucamide | SCHEMBL61278 | N-METHYL-N-DECA

Specifications & Purity

High-purity

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

High-purity

Names and Identifiers

• Pubchem Sid: 504757678
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504757678
• Canonical Smiles: CCCCCCCCCC(=O)N(C)CC(C(C(C(CO)O)O)O)O
• IUPAC Name: N-methyl-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]decanamide
• InChIKey: UMWKZHPREXJQGR-XOSAIJSUSA-N
• INCHI: 1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3/t13-,14+,16+,17+/m0/s1
• Isomeric SMILES: CCCCCCCCCC(=O)N(C)C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
• WGK Germany: 3
• Molecular Weight: 349.46
• Beilstein: 6974359
• Reaxy-Rn: 6974359
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6974359&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Fatty Acyls
      • Subclass Fatty amides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Fatty Acyls
• Subclass: Fatty amides
• Intermediate Tree Nodes: Not available
• Direct Parent: N-acyl amines
• Alternative Parents: Monosaccharides Tertiary carboxylic acid amides Secondary alcohols Polyols Primary alcohols Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Monosaccharide - N-acyl-amine - Tertiary carboxylic acid amide - Carboxamide group - Secondary alcohol - Carboxylic acid derivative - Polyol - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Alcohol - Organic nitrogen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as n-acyl amines. These are compounds containing a fatty acid moiety linked to an amine group through an ester linkage.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in methanol at 50mg/ml. Also soluble in water at 10mg/ml 20 ??°C
• Sensitivity: Moisture sensitive
• Melt Point(°C): 91-93°C
• Molecular Weight: 349.500 g/mol
• XLogP3: 0.600
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 14
• Exact Mass: 349.246 Da
• Monoisotopic Mass: 349.246 Da
• Topological Polar Surface Area: 121.000 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 328.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Yu ZhengQing, Chen SiYing, Huang JianMei, Ding WenXi, Chen YuFeng, Su JunZhi, Yan RuoFeng, Xu LiXin, Song XiaoKai, Li XiangRui.  (2022)  A multiepitope vaccine encoding four Eimeria epitopes with PLGA nanospheres: a novel vaccine candidate against coccidiosis in laying chickens.  VETERINARY RESEARCH,  53  (1): (1-21).  [PMID:35365221] [10.1186/s13567-022-01045-w]

2. Lisha Ye, Tianjiao Wang, Simin Wu, Hui Liu, Feng Liu, Chunqun Wang, Min Hu.  (2024)  Effects of immune response on different nano-adjuvants combined with H11 antigen of Haemonchus contortus.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:39536488] [10.1016/j.intimp.2024.113602]

3. Lisha Ye, Simin Wu, Fuqiang Liu, Juan Zhang, Jie Wan, Chunqun Wang, Hui Liu, Min Hu.  (2025)  Enhancing H11 Protein-Induced Immune Protection Against Haemonchus contortus in Goats: A Nano-Adjuvant Formulation Strategy.  Biology-Basel,  14  (5): (563).  [PMID:40427752] [10.3390/biology14050563]