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N-Desmethyl Clozapine-d8 - ≥98%(CP),≥98 atom% D , CAS No.1189888-77-4

CAS: 1189888-77-4 Cat. No.: N333798 Molecular Weight: 320.85
COA
N-Desmethyl Clozapine-d8 - ≥98%(CP),≥98 atom% D CAS No(1189888-77-4) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(CP),≥98 atom% D
Synonyms
8-Chloro-11-(1-piperazinyl-d8)-5H-dibenzo[B,E][1,4]diazepine hydrochloride | Norclozapine-d8 | Desmethylclozapine-d8 | N-Desmethylclozapine-d8 | 8-Chloro-11-(piperazin-1-yl-2,2,3,3,5,5,6,6-d8)-5H-dibenzo[b,e][1,4]diazepine | N-Desmethylclozapine-d8 | Norc
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Status
Price
Qty
1mg
N333798-1mg
2
$332.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data 3D Structure Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

≥98%(CP),≥98 atom% D for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

N-Desmethylclozapine-d8 is the deuterium labeled N-Desmethylclozapine. N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist.

Specifications

Synonyms
8-Chloro-11-(1-piperazinyl-d8)-5H-dibenzo[B, E][1, 4]diazepine hydrochloride | Norclozapine-d8 | Desmethylclozapine-d8 | N-Desmethylclozapine-d8 | 8-Chloro-11-(piperazin-1-yl-2, 2, 3, 3, 5, 5, 6, 6-d8)-5H-dibenzo[b, e][1, 4]diazepine | N-Desmethylclozapine-d8 | Norc
Specifications & Purity
≥98%(CP), ≥98 atom% D
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥98%(CP), ≥98 atom% D
Names and Identifiers
Canonical SmilesC1CN(CCN1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42
IUPAC Name3-chloro-6-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine
InChIKeyJNNOSTQEZICQQP-UFBJYANTSA-N
INCHI1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19-20H,7-10H2/i7D2,8D2,9D2,10D2
Alternate CAS 6104-71-8（unlabelled）
Molecular Weight 320.85
Reaxy-Rn 762289
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=762289&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
H2526813Certificate of AnalysisApr 26, 2025 N333798
Chemical and Physical Properties
SolubilitySoluble in Ethanol
Melt Point(°C)102-104° C
Solution Calculators
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