N-Myristoyl-glycine - ≥98% , CAS No.14246-55-0

CAS: 14246-55-0 Cat. No.: N338969 Molecular Weight: 285.42

GRADE & PURITY ≥98%

Synonyms

n-tetradecanoylglycine | 84UK82T430 | DTXSID10162047 | NSC622050 | NSC-622050 | AKOS027328012 | 2-(tetradecanoylamino)acetic acid | ?Myristoyl Glycine | 2-tetradecanamidoacetic acid | N-Myristoyl-gly | SCHEMBL343546 | Myristoylglycine | Myristoyl-Gly-OH,

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Application

228,229

Specifications

Synonyms

n-tetradecanoylglycine | 84UK82T430 | DTXSID10162047 | NSC622050 | NSC-622050 | AKOS027328012 | 2-(tetradecanoylamino)acetic acid | ?Myristoyl Glycine | 2-tetradecanamidoacetic acid | N-Myristoyl-gly | SCHEMBL343546 | Myristoylglycine | Myristoyl-Gly-OH,

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Myristoylglycine is an acylglycine with C-14 fatty acid group as the acyl moiety. Acylglycines possess a common amidoacetic acid moiety and are normally minor metabolites of fatty acids. Elevated levels of certain acylglycines appear in the urine and bloo

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504754653
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504754653
• Canonical Smiles: CCCCCCCCCCCCCC(=O)NCC(=O)O
• IUPAC Name: 2-(tetradecanoylamino)acetic acid
• InChIKey: DYUGTPXLDJQBRB-UHFFFAOYSA-N
• INCHI: 1S/C16H31NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-15(18)17-14-16(19)20/h2-14H2,1H3,(H,17,18)(H,19,20)
• Isomeric SMILES: CCCCCCCCCCCCCC(=O)NCC(=O)O
• Molecular Weight: 285.42
• Reaxy-Rn: 1794967
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1794967&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 N-acyl-alpha amino acids and derivatives
              • Level8 N-acyl-alpha amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - N-acyl-alpha amino acids and derivatives
• Direct Parent: N-acyl-alpha amino acids
• Alternative Parents: Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Carboxylic acids Carboximidic acids Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: N-acyl-alpha-amino acid - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carbonyl group - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom.
• External Descriptors: fatty amide - N-acylglycine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: DMF: 10 mg/ml,DMSO: 10 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 0.5 mg/ml
• Refractive Index: n20D1.47
• Boil Point(°C): 469° C at 760 mmHg
• Molecular Weight: 285.420 g/mol
• XLogP3: 5.400
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 285.23 Da
• Monoisotopic Mass: 285.23 Da
• Topological Polar Surface Area: 66.400 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 254.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1