Neuropeptide S (human), Agonist of NPS receptor, CAS No.412938-67-1, Agonist of NPS receptor

CAS: 412938-67-1 Cat. No.: N287329 Molecular Weight: 2187.50 PubChem CID: 44123843
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
N287329-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$499.90
5mg
N287329-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,239.90
10mg
N287329-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,879.90
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Product Name
Neuropeptide S (human), Agonist of NPS receptor, CAS No.412938-67-1
Grade
Moligand™
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Potent endogenous neuropeptide S receptor agonist (EC50= 9.4 nM). Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice.Neuropeptide S human, a neuropeptide, is a potent cognate neuropeptide S receptor (NPSR) ago
Sequence
SFRNGVGTGMKKTSFQRAKS
Action Type
AGONIST
Mechanism of action
Agonist of NPS receptor
CAS
412938-67-1
Molecule Type
Protein
Storage and Shipping
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic Polymers
ClassPolypeptides
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPolypeptides
Alternative Parents Peptides  Arginine and derivatives  Phenylalanine and derivatives  Glutamine and derivatives  Asparagine and derivatives  Methionine and derivatives  Valine and derivatives  N-acyl-L-alpha-amino acids  Serine and derivatives  Alpha amino acid amides  Alanine and derivatives  Amphetamines and derivatives  Beta hydroxy acids and derivatives  N-acyl amines  Guanidines  Secondary alcohols  Secondary carboxylic acid amides  Amino acids  Primary carboxylic acid amides  Monocarboxylic acids and derivatives  Sulfenyl compounds  Dialkylthioethers  Carboxylic acids  Carboximidamides  Imines  Hydrocarbon derivatives  Carbonyl compounds  Organic oxides  Primary alcohols  Monoalkylamines  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Polypeptide - Alpha peptide - Arginine or derivatives - Phenylalanine or derivatives - Glutamine or derivatives - Methionine or derivatives - Asparagine or derivatives - N-acyl-alpha amino acid or derivatives - Valine or derivatives - N-acyl-l-alpha-amino acid - N-acyl-alpha-amino acid - Alpha-amino acid amide - Serine or derivatives - Alanine or derivatives - N-substituted-alpha-amino acid - Amphetamine or derivatives - Alpha-amino acid or derivatives - Beta-hydroxy acid - Monocyclic benzene moiety - Fatty amide - Hydroxy acid - Benzenoid - N-acyl-amine - Fatty acyl - Amino acid or derivatives - Amino acid - Secondary carboxylic acid amide - Secondary alcohol - Primary carboxylic acid amide - Carboxamide group - Guanidine - Dialkylthioether - Sulfenyl compound - Carboximidamide - Thioether - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Primary alcohol - Organic oxygen compound - Amine - Primary amine - Carbonyl group - Organic oxide - Alcohol - Organic nitrogen compound - Organosulfur compound - Imine - Primary aliphatic amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
External Descriptors Not available
Associated Targets(Human)
NPSR1 Tchem Neuropeptide S receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Associated Targets(non-human)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Genetic information
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more
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