O4I1 - ≥98% , CAS No.175135-47-4

CAS: 175135-47-4 Cat. No.: O413882 Summenformel: C₁₆H₁₅NO₂ Molekulargewicht: 253.3 EG-Nummer: 891-076-1

GRADE & PURITY ≥98%

Synonyms

A881638 | EX-A5623 | Z291786494 | 2-(4-[(4-Methoxybenzyl)oxy]phenyl)acetonitrile | Maybridge1_001630 | HY-18771 | 2-(4-((4-Methoxybenzyl)oxy)phenyl)acetonitrile | FT-0610904 | O4I1 | O4I-1 | 2-[4-[(4-methoxyphenyl)methoxy]phenyl]acetonitrile | 2-[4-[(4-Me

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Information

O4I1 O4I1 is a potent Oct3/4 inducer.

Targets

OCT4 ; OCT3

In vitro

O4I1 enhances Oct3/4 gene expression by approximately 2.5- and 4-fold at 10 μM and 20 μM, respectively, increases Oct3/4 protein levels, and promotes Oct3/4 mediated transcriptional activation.

Specifications

Synonyme

A881638 | EX-A5623 | Z291786494 | 2-(4-[(4-Methoxybenzyl)oxy]phenyl)acetonitrile | Maybridge1_001630 | HY-18771 | 2-(4-((4-Methoxybenzyl)oxy)phenyl)acetonitrile | FT-0610904 | O4I1 | O4I-1 | 2-[4-[(4-methoxyphenyl)methoxy]phenyl]acetonitrile | 2-[4-[(4-Me

Spezifikationen & Reinheit

≥98%

Biochemische und physiologische Mechanismen

O4I1 is a potent Oct3/4 inducer.

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥98%

Namen und Kennungen

• Pubchem Sid: 504761885
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504761885
• Kanonisches Lächeln: COC1=CC=C(C=C1)COC2=CC=C(C=C2)CC#N
• IUPAC Name: 2-[4-[(4-methoxyphenyl)methoxy]phenyl]acetonitrile
• InChIKey: QJEJLARVLKHYFW-UHFFFAOYSA-N
• INCHI: 1S/C16H15NO2/c1-18-15-6-4-14(5-7-15)12-19-16-8-2-13(3-9-16)10-11-17/h2-9H,10,12H2,1H3
• Isomere SMILES: COC1=CC=C(C=C1)COC2=CC=C(C=C2)CC#N
• Molekulargewicht: 253.3
• Reaxy-Rn: 14502312
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14502312&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Klasse Benzene and substituted derivatives
      • Subclass Benzyl cyanides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Klasse: Benzene and substituted derivatives
• Subclass: Benzyl cyanides
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzyl cyanides
• Alternative Parents: Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Nitriles Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzyl-cyanide - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Alkyl aryl ether - Ether - Carbonitrile - Nitrile - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Aromatic homomonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as benzyl cyanides. These are organic compounds containing an acetonitrile with one hydrogen replaced by a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

HEK293 (82097 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HFF (3142 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POU5F1 Tbio POU domain, class 5, transcription factor 1 (69 Activities)

Discover Target: POU5F1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NANOG Tbio Homeobox protein NANOG (2 Activities)

Discover Target: NANOG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Zugehörige Ziele (nicht menschlich)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro DMSO: 51 mg/mL (201.34 mM); Ethanol: 1 mg/mL warmed with 50ºC Water: bath (3.94 mM); Water: Insoluble
• Molekulargewicht: 253.290 g/mol
• XLogP3: 3.000
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 253.11 Da
• Monoisotopic Mass: 253.11 Da
• Topological Polar Surface Area: 42.300 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 293.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 175135-47-4, the molecular formula is C16H15NO2, and the molecular weight is 253.3 g/mol. InChIKey QJEJLARVLKHYFW-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.