p-Phthaloyl chloride(TPC) - ≥97% , CAS No.100-20-9

CAS: 100-20-9 Cat. No.: P108668 Molecular Weight: 203.02 Beilstein Registry Number: 607796 EC Number: 202-829-5
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
Terephthaloyl chloride, >=99%, flakes | Terephthalic dichloride | Terephthalic acid dichloride | p-Phthalyl dichloride | Terephthaloyl chloride | Q-201791 | DTXCID506653 | HSDB 5332 | Q7702072 | SCHEMBL68148 | CAS-100-20-9 | terephthalic chloride | CCRIS
Storage
Room temperature,Argon charged,Desiccated,Cool
Shipped In
FedEx DG Service
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Size
Status
Price
Qty
500g
P108668-500g
2
$39.90
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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature,Argon charged,Desiccated,Cool Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 84 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Product Application:

Terephthaloyl chloride acts as a monomer with p-phenylenediamine used in the preparation of polymer viz. poly paraphenylene terephthalamide. It is an active component in performance polymers and aramid fibers, which gives flame resistance, chemical resistance, temperature stability, light weight, and very high strength. It is also used as an effective water scavenger, utilized to stabilize isocyanates and urethane prepolymers. Further, it is used in the preparation of liquid crystalline thermosets by thermal cyclotrimerization of dicyanate compounds of ring substituted bis(4-hydroxyphenyl) terepthalates. In addition to this, it is involved in the condensation reaction with difunctional alfa, µ-diaminopolystyrene to get chain-extended polystyrene containing amide bonds along the polymer backbone.

Specifications

Synonyms
Terephthaloyl chloride, >=99%, flakes | Terephthalic dichloride | Terephthalic acid dichloride | p-Phthalyl dichloride | Terephthaloyl chloride | Q-201791 | DTXCID506653 | HSDB 5332 | Q7702072 | SCHEMBL68148 | CAS-100-20-9 | terephthalic chloride | CCRIS
Specifications & Purity
≥97%
Storage
Room temperature, Argon charged, Desiccated, Cool
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥97%
Names and Identifiers
Pubchem Sid504751359
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504751359
Canonical SmilesC1=CC(=CC=C1C(=O)Cl)C(=O)Cl
IUPAC Namebenzene-1,4-dicarbonyl chloride
InChIKeyLXEJRKJRKIFVNY-UHFFFAOYSA-N
INCHI1S/C8H4Cl2O2/c9-7(11)5-1-2-6(4-3-5)8(10)12/h1-4H
Isomeric SMILES C1=CC(=CC=C1C(=O)Cl)C(=O)Cl
WGK Germany 3
RTECS WZ1797000
UN Number 2923
Packing Group I
Molecular Weight 203.02
Beilstein 607796
Reaxy-Rn 607796
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=607796&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentBenzoic acids and derivatives
Alternative Parents Benzoyl derivatives  Acyl chlorides  Organooxygen compounds  Organochlorides  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Benzoic acid or derivatives - Benzoyl - Acyl halide - Acyl chloride - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organochloride - Organohalogen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzoic acids and derivatives. These are organic compounds containing a carboxylic acid substituent attached to a benzene ring.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
F2604521Certificate of AnalysisJun 11, 2026 P108668
F2604523Certificate of AnalysisJun 11, 2026 P108668
C2117087Certificate of AnalysisJun 08, 2026 P108668
H2231707Certificate of AnalysisMar 11, 2026 P108668
C2202061Certificate of AnalysisSep 09, 2025 P108668
K2111236Certificate of AnalysisAug 02, 2023 P108668
K2111239Certificate of AnalysisAug 02, 2023 P108668
B2323198Certificate of AnalysisMar 02, 2023 P108668
Chemical and Physical Properties
SolubilitySoluble in ethanol, ether and other common organic solvents.
SensitivityMoisture Sensitive
Flash Point(°F)356°F
Flash Point(°C)180℃
Boil Point(°C)259°C
Melt Point(°C)82-84°C
Molecular Weight203.020 g/mol
XLogP34.000
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass201.959 Da
Monoisotopic Mass201.959 Da
Topological Polar Surface Area34.100 Ų
Heavy Atom Count12
Formal Charge0
Complexity173.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
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59. Zhoufeng Wang, Xiubo Long, Bolin Wang, Guojun Cheng, Guoxin Ding, Yingying Liu, Wenlong Yao.  (2024)  Study on the synthesis and properties of a new fluorine-containing copolyarylate.  JOURNAL OF APPLIED POLYMER SCIENCE,  141  (35): (e55891).  [PMID:] [10.1002/app.55891]
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62. Juexin Huang, Jingyi Xia, Sravan Baddi, Yu Zhao, Chuan-liang Feng.  (2025)  Dual-Scale Polarization Engineering of d-Phenylalanine-Based Assemblies for High-Performance Nanogenerators.  ACS Nano,      [PMID:40598888] [10.1021/acsnano.5c03436]
63. Tianmin Tang, Shuying Kong, Junyi Xie, Qiurong Deng, Cong Lai, Shuanshuan Guo, Hao Yu, Jianhua Zhou.  (2025)  Prolonged Release of Bacillus Calmette–Guérin by Floating Microbubbles to Enhance Intravesical Immunotherapy for Bladder Cancer.  ACS Nano,      [PMID:40726143] [10.1021/acsnano.5c06540]
64. Nan Li, Zhaoqing Lu, Doudou Ning, Li Hua, Songfeng E.  (2025)  Mechanically strong heterocyclic aramid nanofiber-based nanopaper via boron nitride nanosheet-incorporated polymerization and assembly of poly(p-phenylene-benzimidazole-terephthalamide).  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.166648]
65. Nan Li, Zhaoqing Lu, Doudou Ning, Li Hua, Songfeng E.  (2025)  Scalable Fabrication of Anisotropic Heterocyclic Aramid Nanofiber Films with Ultrahigh Toughness for Insulation and Thermal Management Applications.  ACS Applied Materials & Interfaces,      [PMID:40625154] [10.1021/acsami.5c10044]
66. Aiting Liu, Zixin Lv, Hao Wang, Xiaowei Zhou, Qinghai Chen, Shuanyan Kang, Quanyuan Zhang, Nanwen Li.  (2025)  Imidazole-Functionalized Polyamide Lithium Ion-Solvating Membranes: A Molecularly Engineered Quasi-Solid Electrolyte for High-Performance Lithium Metal Batteries.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2025.124511]
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75. Jinlei Liu, Si-Cheng Li, Chaofeng Wang, Lilong Gao, Fei Zhou, Lisha Zhou, Qiang Liu, Siyuan Li, Tao Ma, Kunyan Sui.  (2025)  Robust, High-Temperature-Resistant Aramid Nanofiber Separator with Hierarchical Structure for High-Performance Lithium-Ion Batteries.  Small,      [PMID:40589183] [10.1002/smll.202505087]
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78. Wei Guo, Shifan Lu, Liangfan Gong, Zhiping Zhao, Changmei Sun, Cuiqing Teng, Ying Zhang, Rongjun Qu, Ying Wang.  (2025)  In-Situ Synthesized Aramid Nanoparticles for Multiscale Fiber Reinforcement of Polymer Composites.  POLYMER TESTING,      [PMID:] [10.1016/j.polymertesting.2025.109032]
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83. Yongchao He, Hanzhao Kuang, Xiaoqing Liu, Hai Zheng, Yinhang Zhang, Xuan Wang, Yinghua Huang, Jinjing Tang, Feng Wang, Xudong Cui, Mingbo Yang, Hang Chen, Yanhao Huang.  (2026)  2D-QSAR-DFT assisted design of unimolecular coumarin oxime ester photoinitiators with terminal fluorobenzene moieties for radical polymerization.  POLYMER,      [PMID:] [10.1016/j.polymer.2026.129738]
84. Wei Guo, Xiangjun Gong, Shifan Lu, Liangfan Gong, Zixuan Guo, Meixue Sun, Jinhua Hui, Yuheng Zhang, Changmei Sun, Rongjun Qu.  (2026)  In Situ-Grown Aramid Nanomaterials as Multifunctional Reinforcements for High-Performance PVC Composites.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.70652]
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