Determine the necessary mass, volume, or concentration for preparing a solution.
PARP7-IN-14 - ≥98% , CAS No.P659390
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items
Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
PARP7-IN-14 (I-1) is a potent and selective PARP7 inhibitor with an IC 50 value of 7.6 nM. PARP7-IN-14 has anticancer activity.
Appearance:Solid
In Vitro:PARP7-IN-14 (I-1) inhibits CT26 cell lines with the IC 50 value of 12.85 μM and shows some anti-proliferative effect on tumors. PARP7-IN-14 (I-1) (0-4 μM) promotes mRNA expression levels of IFN-β and CXCL10 and induces a concentration-dependent incre
In Vivo:PARP7-IN-14 (I-1) (p.o., 25-100mg/kg, twice daily, 14 days) significantly inhibits tumour growth in CT26 tumour-bearing mice, with a 67% reduction in mean tumour volume in mice treated with I-1 compared to controls, and does not cause weight loss or othe
Biological Activity:PARP7-IN-14 (I-1) is a potent and selective PARP7 inhibitor with an IC 50 value of 7.6 nM. PARP7-IN-14 has anticancer activity.
Specifications
Specifications & Purity
≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
| Canonical Smiles | O=C1NN=CC(N[C@H](CN2CC(C(N3CCN(CC3)C4=NC=C(C=N4)C(F)(F)F)=O)C2)C)=C1C(F)(F)F |
|---|---|
| Molecular Weight | 534.46 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews
Customer Reviews
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.