Phe-Met-Arg-Phe, amide acetate , CAS No.152165-14-5

CAS: 152165-14-5 Cat. No.: P1437280 PubChem CID: 10100083

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Phe-Met-Arg-Phe, amide acetate dose dependently (ED 50 =23 nM) activates a K + current in the peptidergic caudodorsal neurons.

Specifications

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ACTIVATOR

Names and Identifiers

• Canonical Smiles: CSCCC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)N
• IUPAC Name: (2S)-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-(diaminomethylideneamino)pentanamide
• InChIKey: WCSPDMCSKYUFBX-ZJZGAYNASA-N
• INCHI: 1S/C29H42N8O4S/c1-42-16-14-23(35-26(39)21(30)17-19-9-4-2-5-10-19)28(41)36-22(13-8-15-34-29(32)33)27(40)37-24(25(31)38)18-20-11-6-3-7-12-20/h2-7,9-12,21-24H,8,13-18,30H2,1H3,(H2,31,38)(H,35,39)(H,36,41)(H,37,40)(H4,32,33,34)/t21-,22-,23-,24-/m0/s1
• Isomeric SMILES: CSCC[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CC=CC=C2)N
• Alternate CAS: 64190-70-1
• PubChem CID: 10100083
• MeSH Entry Terms: FMRF;FMRF amide;FMRF NH2;FMRF-amide;FMRF-NH2;FMRFamide;FMRFamide, (D-Arg)-Isomer;FMRFamide, (D-Met)-Isomer;FMRFamide, (D-Phe)-Isomer;FMRFamide, (D-phenylalanine)-Isomer;Phe Met Arg Phe amide;Phe-Met-Arg-Phe-amide;Phe-Met-Arg-Phe-NH2

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Phenylalanine and derivatives Methionine and derivatives N-acyl-alpha amino acids and derivatives Alpha amino acid amides Amphetamines and derivatives Aralkylamines N-acyl amines Secondary carboxylic acid amides Primary carboxylic acid amides Guanidines Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Carboximidamides Dialkylthioethers Organic oxides Carbonyl compounds Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Alpha-oligopeptide - Phenylalanine or derivatives - Methionine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - Aralkylamine - Fatty acyl - Monocyclic benzene moiety - N-acyl-amine - Benzenoid - Fatty amide - Guanidine - Carboxamide group - Secondary carboxylic acid amide - Primary carboxylic acid amide - Amino acid or derivatives - Dialkylthioether - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Sulfenyl compound - Carboximidamide - Thioether - Hydrocarbon derivative - Amine - Organic oxide - Carbonyl group - Organic oxygen compound - Primary aliphatic amine - Organic nitrogen compound - Primary amine - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y